Reactome | Tetracycline antibiotics bind to 16S rRNA

Schema > Reaction > Entries

authored	[InstanceEdit:9912772] Stephan, Ralf, 2024-06-10
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9912790] Stephan, Ralf, 2024-06-10
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9912784
disease	[Disease:3134792] bacterial infectious disease
displayName	Tetracycline antibiotics bind to 16S rRNA
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9638771] Action of antimicrobials - Homo sapiens
input	[EntityWithAccessionedSequence:R-ECO-9912780] 16S rRNA [cytosol] [Complex:R-ALL-9913101] tetracyclines:Mg2+ [cytosol]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9912787] Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance [LiteratureReference:9912794] rRNA Binding Sites and the Molecular Mechanism of Action of the Tetracyclines [LiteratureReference:9912786] Mapping of the second tetracycline binding site on the ribosomal small subunit of E.coli
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	Tetracycline antibiotics bind to 16S rRNA
output	[Complex:R-ECO-9912779] 16S rRNA:tetracyclines:Mg2+ [cytosol]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9912784
summation	[Summation:9912775] It is generally assumed that tetracycline antibiotics bind t...

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