Reactome | DppBCDF transports heme to cytosol

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DppBCDF transports heme to cytosol Show undefined attributes

authored	[InstanceEdit:9927596] Stephan, Ralf, 2024-11-08
catalystActivity	[CatalystActivity:9927931] heme transmembrane transporter activity of DppBCDF [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9927925] Stephan, Ralf, 2024-11-09
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9927930
disease	[Disease:3134792] bacterial infectious disease
displayName	DppBCDF transports heme to cytosol
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9927020] Heme assimilation - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-ECO-9927603] PBP:heme [periplasmic space]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9927599] The housekeeping dipeptide permease is the Escherichia coli heme transporter and functions with two optional peptide binding proteins
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	DppBCDF transports heme to cytosol
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-9036182] heme b [cytosol] [DefinedSet:R-ECO-9927594] PBP [periplasmic space] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-9927609] PBP binds heme - Homo sapiens
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9927930
summation	[Summation:9927924] Inner E.coli cell membrane located ABC transporter Dipeptide...

Referrals

(hasEvent)	[Pathway:R-HSA-9927020] Heme assimilation
(precedingEvent)	[NegativePrecedingEvent:9939563] Futile Cycle: DppBCDF transports heme to cytosol

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