Reactome | EmrE dimer exports xenobiotics to periplasm

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EmrE dimer exports xenobiotics to periplasm Show undefined attributes

authored	[InstanceEdit:9931201] Stephan, Ralf, 2024-12-11
catalystActivity	[CatalystActivity:9931578] xenobiotic transmembrane transporter activity of EmrE dimer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9931555] Stephan, Ralf, 2024-12-12
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9931565
disease	[Disease:3134792] bacterial infectious disease
displayName	EmrE dimer exports xenobiotics to periplasm
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9913143] Antimicrobial resistance - Homo sapiens
input	[DefinedSet:R-ALL-9931557] EmrE cargo [cytosol] 2 × [SimpleEntity:R-ALL-8858135] H+ [periplasmic space]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9931165] Disinfectant resistance in bacteria: Mechanisms, spread, and resolution strategies [LiteratureReference:9931566] Cloning of the ethidium efflux gene from Escherichia coli [LiteratureReference:9931564] Cloning and characterization of the mvrC gene of Escherichia coli K-12 which confers resistance against methyl viologen toxicity [LiteratureReference:9931573] Analyzing conformational changes in the transport cycle of EmrE
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	EmrE dimer exports xenobiotics to periplasm
output	[DefinedSet:R-ALL-9931568] EmrE cargo [periplasmic space] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9931565
summation	[Summation:9931577] E.coli EmrE dimer transports molecules of polyaromatic catio...

Referrals

(hasEvent)

[Pathway:R-HSA-9913143] Antimicrobial resistance

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