Reactome | FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol

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FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol Show undefined attributes

authored	[InstanceEdit:9638337] Stephan, Ralf, 2019-02-21
catalystActivity	[CatalystActivity:9638318] ferric-enterobactin transmembrane transporter activity of FepDGC [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:1222638] periplasmic space [Compartment:876] plasma membrane
created	[InstanceEdit:9911604] Stephan, Ralf, 2024-06-03
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9911603
deleted	[Deleted:9911637] Deletion of instance: 9638401
disease	[Disease:3134792] bacterial infectious disease
displayName	FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9638334] Iron assimilation using enterobactin - Homo sapiens
followingEvent	[Reaction:R-HSA-9911599] Fes hydrolyses ferrienterobactin to DHBS - Homo sapiens [Reaction:R-HSA-9927945] YqjH reduces FeEnt - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-ECO-9638328] FeEnt:FepB [periplasmic space]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9638421] Docking of the periplasmic FecB binding protein to the FecCD transmembrane proteins in the ferric citrate transport system of Escherichia coli [LiteratureReference:9638406] Identification of hydrophobic proteins FepD and FepG of the Escherichia coli ferrienterobactin permease [LiteratureReference:9638377] Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli [LiteratureReference:9638388] Organization of genes encoding membrane proteins of the Escherichia coli ferrienterobactin permease
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-9638381] FeEnt [cytosol] [EntityWithAccessionedSequence:R-ECO-9638312] FepB [periplasmic space] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-9911597] Ferrienterobactin binds to FepB - Homo sapiens
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9911603
summation	[Summation:9638380] The ferrienterobactin transporter complex composed of ferric...

Referrals

(replacementInstances)	[Deleted:9911637] Deletion of instance: 9638401
(precedingEvent)	[Reaction:R-HSA-9911599] Fes hydrolyses ferrienterobactin to DHBS [NegativePrecedingEvent:9939562] Futile Cycle: FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol [Reaction:R-HSA-9927945] YqjH reduces FeEnt
(hasEvent)	[Pathway:R-HSA-9638334] Iron assimilation using enterobactin

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