Reactome | p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane]

catalystActivities	[CatalystActivity:975856] protein serine/threonine kinase activity of p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-975874] Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex - Homo sapiens
created	[InstanceEdit:975863] Shamovsky, V, 2010-10-06
dbId	975872
displayName	p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane]
hasComponent	[Complex:R-HSA-975870] p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] 4 × [EntityWithAccessionedSequence:R-HSA-937031] p-T209-IRAK1 [plasma membrane]
inDisease	false
maxDepth	7
modified	[InstanceEdit:8959586] Weiser, JD
name	p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10
producedByEvent	[Reaction:R-HSA-975878] First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR - Homo sapiens
relatedSpecies	[Species:159879] Escherichia coli
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-975872
updateTrackers	[UpdateTracker:9896392] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v60:[removeSpecies, updateContainedComponent] [UpdateTracker:9873341] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9870237] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v38:[updateContainedComponent] [UpdateTracker:9871080] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v39:[updateContainedComponent]

p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] Show undefined attributes

Referrals

(updatedInstance)	[UpdateTracker:9896392] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v60:[removeSpecies, updateContainedComponent] [UpdateTracker:9873341] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9870237] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v38:[updateContainedComponent] [UpdateTracker:9871080] Update Tracker - [Complex:975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] - v39:[updateContainedComponent]
(output)	[Reaction:R-HSA-975878] First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR
(input)	[Reaction:R-HSA-975874] Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex
(physicalEntity)	[CatalystActivity:975856] protein serine/threonine kinase activity of p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane]