Reactome | Toll Like Receptor 10 (TLR10) Cascade

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Toll Like Receptor 10 (TLR10) Cascade Show undefined attributes

authored	[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
created	[InstanceEdit:168183] Gillespie, ME, 2005-11-10 16:33:34
crossReference	[DatabaseIdentifier:12819451] BioModels Database:BIOMD0000000477
dbId	168142
displayName	Toll Like Receptor 10 (TLR10) Cascade
edited	[InstanceEdit:1485578] Shamovsky, V, 2011-08-12
eventOf	[Pathway:R-HSA-168898] Toll-like Receptor Cascades - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:263009] toll-like receptor 10 signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-168947] Ligand binds to TLR10 - Homo sapiens [Pathway:R-HSA-975871] MyD88 cascade initiated on plasma membrane - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
literatureReference	[LiteratureReference:181163] Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88 [LiteratureReference:976262] The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer
maxDepth	7
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Toll Like Receptor 10 (TLR10) Cascade
orthologousEvent	[Pathway:R-MMU-168142] Toll Like Receptor 10 (TLR10) Cascade - Mus musculus [Pathway:R-PFA-168142] Toll Like Receptor 10 (TLR10) Cascade - Plasmodium falciparum [Pathway:R-SCE-168142] Toll Like Receptor 10 (TLR10) Cascade - Saccharomyces cerevisiae [Pathway:R-SPO-168142] Toll Like Receptor 10 (TLR10) Cascade - Schizosaccharomyces pombe [Pathway:R-DDI-168142] Toll Like Receptor 10 (TLR10) Cascade - Dictyostelium discoideum [Pathway:R-CEL-168142] Toll Like Receptor 10 (TLR10) Cascade - Caenorhabditis elegans [Pathway:R-DME-168142] Toll Like Receptor 10 (TLR10) Cascade - Drosophila melanogaster [Pathway:R-GGA-168142] Toll Like Receptor 10 (TLR10) Cascade - Gallus gallus [Pathway:R-XTR-168142] Toll Like Receptor 10 (TLR10) Cascade - Xenopus tropicalis [Pathway:R-DRE-168142] Toll Like Receptor 10 (TLR10) Cascade - Danio rerio [Pathway:R-SSC-168142] Toll Like Receptor 10 (TLR10) Cascade - Sus scrofa [Pathway:R-BTA-168142] Toll Like Receptor 10 (TLR10) Cascade - Bos taurus [Pathway:R-CFA-168142] Toll Like Receptor 10 (TLR10) Cascade - Canis familiaris [Pathway:R-RNO-168142] Toll Like Receptor 10 (TLR10) Cascade - Rattus norvegicus
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2006-11-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188962] Gale M, Jr, 2006-10-31 16:45:01 [InstanceEdit:1186998] Gillespie, ME, 2011-02-10
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-168142
summation	[Summation:188308] Little is known about TLR10 ligands. It has been established...
updateTrackers	[UpdateTracker:9782068] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v59:[updateIndirectRLE] [UpdateTracker:9790212] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v34:[removeHasEvent] [UpdateTracker:9789244] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v38:[addLiteratureReference, updateContainedPathway] [UpdateTracker:9790102] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v35:[modifyText] [UpdateTracker:9788140] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v43:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9786634] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v49:[updateContainedPathway] [UpdateTracker:9775087] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v80:[updateContainedPathway] [UpdateTracker:9778080] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v68:[updateContainedPathway] [UpdateTracker:9788582] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v41:[updateIndirectRLE] [UpdateTracker:9784300] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v54:[updateContainedPathway] [UpdateTracker:9790640] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v33:[updateContainedPathway] [UpdateTracker:9774707] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v81:[updateContainedPathway] [UpdateTracker:9784634] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v53:[updateContainedPathway] [UpdateTracker:9785240] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v52:[updateContainedPathway] [UpdateTracker:9789708] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v37:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9789964] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v36:[addHasEvent, modifyText, updateContainedRLE] [UpdateTracker:9788436] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v42:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9791807] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v25:[updateIndirectRLE]

Referrals

(updatedInstance)

[UpdateTracker:9782068] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v59:[updateIndirectRLE]
[UpdateTracker:9790212] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v34:[removeHasEvent]
[UpdateTracker:9789244] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v38:[addLiteratureReference, updateContainedPathway]
[UpdateTracker:9790102] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v35:[modifyText]
[UpdateTracker:9788140] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v43:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786634] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v49:[updateContainedPathway]
[UpdateTracker:9775087] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v80:[updateContainedPathway]
[UpdateTracker:9778080] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v68:[updateContainedPathway]
[UpdateTracker:9788582] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v41:[updateIndirectRLE]
[UpdateTracker:9784300] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v54:[updateContainedPathway]
[UpdateTracker:9790640] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v33:[updateContainedPathway]
[UpdateTracker:9774707] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v81:[updateContainedPathway]
[UpdateTracker:9784634] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v53:[updateContainedPathway]
[UpdateTracker:9785240] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v52:[updateContainedPathway]
[UpdateTracker:9789708] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v37:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9789964] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v36:[addHasEvent, modifyText, updateContainedRLE]
[UpdateTracker:9788436] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v42:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9791807] Update Tracker - [Pathway:168142] Toll Like Receptor 10 (TLR10) Cascade - v25:[updateIndirectRLE]

(hasEvent)

[Pathway:R-HSA-168898] Toll-like Receptor Cascades

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