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ILF3 [nucleoplasm]
Stable Identifier
R-HSA-9760401
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
ILF3 (DRBP76), Interleukin enhancer-binding factor 3, ILF3_HUMAN
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Regulation of Homotypic Cell-Cell Adhesion (Homo sapiens)
Regulation of Expression and Function of Type II Classical Cadherins (Homo sapiens)
Regulation of CDH11 Expression and Function (Homo sapiens)
Regulation of CDH11 gene transcription (Homo sapiens)
CDH11 gene is transcribed into nascent CDH11 mRNA (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:CDH11 gene [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:HOXC8:CDH11 gene [nucleoplasm] (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3 and HOXC8 bind CDH11 gene promoter (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:HOXC8:CDH11 gene [nucleoplasm] (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3 binds CDH11 gene promoter (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:CDH11 gene [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3 binds HOXC8 (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
ILF3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12906 ILF3
Gene Names
ILF3, DRBF, MPHOSPH4, NF90
Chain
chain:1-894
Reference Genes
BioGPS Gene:3609 ILF3
COSMIC (genes):ILF3 ILF3
CTD Gene:3609 ILF3
dbSNP Gene:3609 ILF3
ENSEMBL:ENSG00000129351 ILF3
ENSEMBL_homo_sapiens_GENE:ENSG00000129351.18 ILF3
HGNC:6038 ILF3
KEGG Gene (Homo sapiens):3609 ILF3
Monarch:3609 ILF3
NCBI Gene:3609 ILF3
OMIM:603182 ILF3
UCSC:Q12906 ILF3
Reference Transcript
RefSeq:NM_153464.2 ILF3
RefSeq:NM_004516.3 ILF3
RefSeq:XM_017026763.1 ILF3
RefSeq:NM_017620.2 ILF3
RefSeq:NM_001137673.1 ILF3
RefSeq:XM_011527984.2 ILF3
RefSeq:NM_012218.3 ILF3
Other Identifiers
11718546_s_at
11718547_a_at
11718548_x_at
11718549_a_at
11722560_a_at
11740781_a_at
11750988_a_at
11754908_a_at
16858235
208930_PM_s_at
208930_s_at
208931_3p_s_at
208931_PM_s_at
208931_s_at
211375_PM_s_at
211375_s_at
217804_PM_s_at
217804_s_at
217805_PM_at
217805_at
32751_at
3609
3820666
3820667
3820673
3820674
3820675
3820678
3820681
3820683
3820684
3820685
3820686
3820687
3820689
3820690
3820693
3820694
3820695
3820696
3820697
3820698
3820699
3820700
3820701
3820702
3820703
3820704
3820705
3820706
3820707
3820711
3820712
3820713
3820714
3820715
3820716
3820717
3820718
3820719
3820720
3820721
3820723
40845_at
40846_g_at
55611_at
8025697
A_23_P218456
A_23_P329152
A_23_P434944
GE55333
GE81404
GO:0001618
GO:0003677
GO:0003723
GO:0003725
GO:0003727
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005739
GO:0005829
GO:0006351
GO:0006355
GO:0006468
GO:0016020
GO:0017148
GO:0035925
GO:0036211
GO:0043226
GO:0045071
GO:0045892
GO:0045893
GO:0046718
GO:0051607
GO:0098542
GO:1990904
HMNXSV003030253
HMNXSV003031325
HMNXSV003053914
Hs.256583.1.A1_3p_a_at
ILMN_1669584
ILMN_1698463
PH_hs_0013495
TC19000182.hg
U10324_at
g13111838_3p_s_at
g5006601_3p_a_at
Participates
as an input of
ILF3 binds CDH11 gene promoter (Homo sapiens)
ILF3 binds HOXC8 (Homo sapiens)
as a component of
ILF3:CDH11 gene [nucleoplasm] (Homo sapiens)
ILF3:HOXC8 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
p-T188,T315-ILF3 [cytosol]
ILF3 [cytosol]
Inferred To
ilf3a [nucleoplasm]
(Danio rerio)
ILF3 [nucleoplasm]
(Bos taurus)
ILF3 [nucleoplasm]
(Canis familiaris)
ILF3 [nucleoplasm]
(Gallus gallus)
ILF3 [nucleoplasm]
(Sus scrofa)
Zn72D [nucleoplasm]
(Drosophila melanogaster)
ilf3 [nucleoplasm]
(Xenopus tropicalis)
zfr-1 [nucleoplasm]
(Caenorhabditis elegans)
Ilf3 [nucleoplasm]
(Mus musculus)
Ilf3 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
XP_016882252.1
,
NP_060090.2
,
NP_036350.2
,
NP_703194.1
,
NP_004507.2
,
XP_011526286.2
,
NP_001131145.1
OpenTargets
ENSG00000129351
GeneCards
Q12906
HPA
ENSG00000129351-ILF3
Ensembl
ENST00000407004
,
ENST00000589998
,
ENSP00000468181
,
ENST00000588657
,
ENSP00000468156
,
ENST00000590261
,
ENST00000250241
,
ENSG00000129351
,
ENSP00000250241
,
ENSP00000465219
,
ENSP00000465515
,
ENSP00000384660
,
ENST00000592763
PRO
Q12906
Pharos - Targets
Q12906
PDB
2L33
,
7RJQ
,
7RJM
,
3P1X
Interactors (48)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12905 ILF2
5
ILF2 [ficolin-1-rich granule lumen]
(R-HSA-6801001)
ILF2 [extracellular region]
(R-HSA-6799684)
ILF2 [specific granule lumen]
(R-HSA-6799611)
ILF2 [tertiary granule lumen]
(R-HSA-6800995)
ILF2 [cytosol]
(R-HSA-9836392)
0.812
10
UniProt:P67809 YBX1
5
p-S32,S36-YBX1 [nucleoplasm]
(R-HSA-9733227)
p-S32,S36-YBX1 [cytosol]
(R-HSA-9736837)
YBX1 [cytosol]
(R-HSA-9736840)
YBX1 [nucleoplasm]
(R-HSA-72041)
YBX1 [extracellular region]
(R-HSA-9017791)
0.662
6
UniProt:Q99873 PRMT1
2
PRMT1 [cytosol]
(R-HSA-9632173)
PRMT1 [nucleoplasm]
(R-HSA-3215140)
0.656
3
UniProt:P07910 HNRNPC
3
HNRNPC [cytosol]
(R-HSA-9715136)
SUMO1-K250-HNRNPC [nucleoplasm]
(R-HSA-4570543)
HNRNPC [nucleoplasm]
(R-HSA-71933)
0.643
3
UniProt:Q05127 VP35
0.576
6
UniProt:P22626 HNRNPA2B1
2
HNRNPA2B1 [extracellular exosome]
(R-HSA-8950304)
HNRNPA2B1 [nucleoplasm]
(R-HSA-71929)
0.564
3
UniProt:P09234 SNRPC
1
SNRPC [nucleoplasm]
(R-HSA-8865876)
0.547
2
UniProt:P03496 NS
2
NS1 [nucleoplasm]
(R-FLU-169113)
NS1 [cytosol]
(R-FLU-169118)
0.547
3
UniProt:Q9UL40 ZN346
0.527
2
UniProt:P09651 HNRNPA1
2
HNRNPA1 [cytosol]
(R-HSA-9727902)
HNRNPA1 [nucleoplasm]
(R-HSA-71927)
0.527
2
UniProt:Q7L2E3 DHX30
0.527
2
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.527
3
UniProt:P18621 RPL17
1
RPL17 [cytosol]
(R-HSA-72418)
0.527
2
UniProt:P14866 HNRNPL
1
HNRNPL [nucleoplasm]
(R-HSA-71947)
0.527
3
UniProt:Q9Y6M1 IGF2BP2
1
IGF2BP2 [cytosol]
(R-HSA-428302)
0.527
3
UniProt:Q08211 DHX9
3
DHX9 [nucleoplasm]
(R-HSA-53517)
DHX9 [cytosol]
(R-HSA-847700)
p-DHX9 [cytosol]
(R-HSA-9836168)
0.527
4
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
3
UniProt:Q07020 RPL18
1
RPL18 [cytosol]
(R-HSA-72420)
0.527
2
UniProt:P05387 RPLP2
1
RPLP2 [cytosol]
(R-HSA-72400)
0.527
2
UniProt:P46778 RPL21
1
RPL21 [cytosol]
(R-HSA-72426)
0.527
2
UniProt:P05388 RPLP0
1
RPLP0 [cytosol]
(R-HSA-72396)
0.527
2
UniProt:P55265 ADAR
2
ADAR1 [cytosol]
(R-HSA-9835955)
ADAR [nucleoplasm]
(R-HSA-53939)
0.527
2
UniProt:Q9NZB2 F120A
0.527
2
UniProt:Q9BZE4 GTPB4
0.527
2
UniProt:Q9NUL3 STAU2
0.527
2
UniProt:O75569 PRKRA
2
p-S246,S287-PRKRA [cytosol]
(R-HSA-9834791)
PRKRA [cytosol]
(R-HSA-2399897)
0.527
2
UniProt:P35637 FUS
1
FUS [nucleoplasm]
(R-HSA-72040)
0.527
2
UniProt:O95793 STAU1
0.527
2
UniProt:P19525 EIF2AK2
5
p-EIF2AK2 [nucleoplasm]
(R-HSA-9836332)
SUMO-EIF2AK2 [cytosol]
(R-HSA-9834829)
ISG15-EIF2AK2 [cytosol]
(R-HSA-9833968)
p-EIF2AK2 [cytosol]
(R-HSA-9833834)
EIF2AK2 [cytosol]
(R-HSA-168699)
0.527
2
UniProt:Q8TDN6 BRX1
0.527
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
4
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.527
2
UniProt:Q8IY81 FTSJ3
1
FTSJ3 [nucleoplasm]
(R-HSA-6791507)
0.527
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.527
2
UniProt:Q96SI9 STRBP
0.527
2
UniProt:Q96CT7 CC124
0.527
2
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.527
2
UniProt:Q13523 PRPF4B
1
PRPF4B [nucleoplasm]
(R-HSA-9769525)
0.527
2
UniProt:P40429 RPL13A
2
p-RPL13A [cytosol]
(R-HSA-156829)
RPL13A [cytosol]
(R-HSA-72412)
0.527
2
UniProt:Q9NZI8 IGF2BP1
1
IGF2BP1 [cytosol]
(R-HSA-428366)
0.527
4
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.527
3
UniProt:Q00839 HNRNPU
1
HNRNPU [nucleoplasm]
(R-HSA-71953)
0.527
2
UniProt:P14866-1 HNRNPL
0.499
2
UniProt:P08325 MATRX
0.499
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
9
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE
0.462
2
UniProt:Q8IUH3 RBM45
0.462
2
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