p-S158,S221-ELAVL1 [cytosol]

Stable Identifier
R-HSA-450376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
HuR with phosphoserine221 and phosphoserine158, ELAV-like protein 1, ELAV1_HUMAN, ELAVL1, HuR
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q15717 ELAVL1
Gene Names
ELAVL1, HUR
Chain
initiator methionine:1, chain:2-326
Reference Genes
BioGPS Gene:1994 ELAVL1
COSMIC (genes):ELAVL1 ELAVL1
CTD Gene:1994 ELAVL1
dbSNP Gene:1994 ELAVL1
ENSEMBL:ENSG00000066044 ELAVL1
HGNC:3312 ELAVL1
KEGG Gene (Homo sapiens):1994 ELAVL1
Monarch:1994 ELAVL1
NCBI Gene:1994 ELAVL1
OMIM:603466 ELAVL1
UCSC:Q15717 ELAVL1
Reference Transcript
Other Identifiers
0001980039
11716528_at
11716529_a_at
11716530_at
11716531_at
11747207_a_at
16868053
1994
201726_at
201727_s_at
227746_at
244660_at
3848687
3848688
3848690
3848691
3848692
3848693
3848694
3848695
3848696
3848697
3848698
3848699
3848700
3848701
3848702
3848705
3848711
3848720
3848734
3848741
39384_at
59058_at
59834_at
8033479
A_23_P208477
A_23_P388681
A_32_P200165
GE59120
GE787419
GO:0000398
GO:0003674
GO:0003676
GO:0003723
GO:0003725
GO:0003729
GO:0003730
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005829
GO:0006397
GO:0006412
GO:0006606
GO:0006810
GO:0006913
GO:0008150
GO:0009056
GO:0009058
GO:0010494
GO:0015031
GO:0016020
GO:0016441
GO:0019899
GO:0019901
GO:0022607
GO:0032991
GO:0034641
GO:0034655
GO:0035198
GO:0035925
GO:0042803
GO:0043226
GO:0043488
GO:0045727
GO:0048255
GO:0051260
GO:0060965
GO:0065003
GO:0070935
GO:0098794
GO:0098978
GO:1990904
GO:2000036
HMNXSV003012794
Hs.129572.0.A1_3p_at
Hs.184492.0.A1_3p_at
ILMN_1685816
ILMN_1764873
PH_hs_0029372
TC19001125.hg
U38175_at
g13097227_3p_at
g4503550_3p_a_at
Participates
as a component of
Other forms of this molecule
ELAVL1 [nucleoplasm]
p-S158,S221-ELAVL1 [nucleoplasm]
p-S221,S318-ELAVL1 [nucleoplasm]
ELAVL1 [cytosol]
p-S221,S318-ELAVL1 [cytosol]
Inferred To
phospho-Rbp9 [cytosol] (Drosophila melanogaster)
phospho-Elavl1 [cytosol] (Mus musculus)
phospho-Elavl1 [cytosol] (Rattus norvegicus)
phospho-fne [cytosol] (Drosophila melanogaster)
Homologues of p-S158,S221-ELAVL1 [cytosol] (Drosophila melanogaster)
phospho-elavl1 [cytosol] (Xenopus tropicalis)
phospho-elavl1a [cytosol] (Danio rerio)
phospho-elav [cytosol] (Drosophila melanogaster)
phospho-ELAVL1 [cytosol] (Bos taurus)
phospho-ELAVL1 [cytosol] (Canis familiaris)
phospho-ELAVL1 [cytosol] (Sus scrofa)
Modified Residues
Name
O-phospho-L-serine at 158
Coordinate
158
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 221
Coordinate
221
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (10)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P54253 ATX1      0.666 7
 UniProt:Q13148 TADBP      0.61 7
 UniProt:O00560 SDCBP  3 0.556 3
 UniProt:Q15717 ELAVL1  6 0.553 2
 UniProt:Q99IB8-PRO_0000045602      0.547 2
 UniProt:P0DTC9 N  13 0.527 2
 IntAct:EBI-20218183 CD9      0.524 3
 IntAct:EBI-25438148 LNC      0.524 3
 IntAct:EBI-20218130 CALM2      0.524 3
 UniProt:P11387 TOP1  2 0.462 3
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