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RBM5 [nucleoplasm]
Stable Identifier
R-HSA-72049
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RBM 5, RNA-binding protein 5, RNA binding motif protein 5, Putative tumor suppressor LUCA15, G15 protein
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
RBM5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P52756 RBM5
Gene Names
RBM5, H37, LUCA15
Chain
chain:1-815
Reference Genes
BioGPS Gene:10181 RBM5
COSMIC (genes):RBM5 RBM5
CTD Gene:10181 RBM5
dbSNP Gene:10181 RBM5
ENSEMBL:ENSG00000003756 RBM5
HGNC:9902 RBM5
KEGG:hsa:10181 RBM5
Monarch:10181 RBM5
NCBI Gene:10181 RBM5
OMIM:606884 RBM5
UCSC:P52756 RBM5
Reference Transcript
RefSeq:XM_017005503.1 RBM5
RefSeq:NM_005778.3 RBM5
Other Identifiers
10181
11716007_a_at
11716008_x_at
11752280_a_at
11752281_x_at
11754588_a_at
11763377_a_at
1556_at
16940877
201394_PM_s_at
201394_s_at
201395_PM_at
201395_at
209936_PM_at
209936_at
230742_3p_at
230742_PM_at
230742_at
2622470
2622471
2622473
2622475
2622476
2622477
2622478
2622486
2622487
2622488
2622489
2622490
2622491
2622492
2622493
2622494
2622495
2622496
2622497
2622498
2622499
2622500
2622502
2622503
2622504
2622505
2622506
2622507
2622508
2622509
2622510
2622511
2622512
2622513
2622514
2622515
2622516
2622517
2622518
2622519
2622520
2622521
2622522
2622524
2622525
2622526
2622527
2622528
2622529
2622530
2622531
2622532
2622533
2622534
2622539
32804_at
55424_at
78085_at
8079869
89864_at
A_14_P103288
A_14_P115247
A_23_P18276
A_24_P328646
A_24_P919510
GE61282
GO:0000245
GO:0000381
GO:0000398
GO:0003676
GO:0003677
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0006396
GO:0006397
GO:0006915
GO:0008285
GO:0008380
GO:0012501
GO:0016071
GO:0043065
GO:0043226
GO:0046872
GO:0065003
HMNXSV003038498
Hs.91216.0.A1_3p_at
ILMN_1786893
PH_hs_0025747
TC03002333.hg
TC03003352.hg
U23946_at
g1244403_3p_a_at
g5032030_3p_at
g9801844_3p_at
Participates
as an input of
Formation of the Spliceosomal A complex (Homo sapiens)
as a component of
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C Complex [nucleoplasm] (Homo sapiens)
as an output of
Formation of the Spliceosomal B complex (Homo sapiens)
Inferred To
rbm5 [nucleoplasm]
(Xenopus tropicalis)
RBM10 [nucleoplasm]
(Gallus gallus)
RBM5 [nucleoplasm]
(Bos taurus)
RBM5 [nucleoplasm]
(Canis familiaris)
RBM5 [nucleoplasm]
(Dictyostelium discoideum)
RBM5 [nucleoplasm]
(Schizosaccharomyces pombe)
RBM5 [nucleoplasm]
(Sus scrofa)
Rbm5 [nucleoplasm]
(Mus musculus)
Rbm5 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of RBM5 [nucleoplasm]
(Plasmodium falciparum)
rbm-5 [nucleoplasm]
(Caenorhabditis elegans)
Dmel\CG4887 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_005769.1
,
XP_016860992.1
OpenTargets
ENSG00000003756
ENSEMBL
ENSP00000419534
,
ENST00000347869
,
ENSP00000343054
,
ENST00000469838
HPA
ENSG00000003756-RBM5
PRO
P52756
Pharos - Targets
P52756
GlyGen
P52756
PDB
2LKZ
,
7PCV
,
5MF9
,
5MFY
,
7PDV
,
2LK1
,
2LK0
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43143 DHX15
1
DHX15 [nucleoplasm]
(R-HSA-5688097)
0.806
15
UniProt:Q9UMS4 PRPF19
1
PRPF19 [nucleoplasm]
(R-HSA-5420907)
0.736
8
UniProt:P26368 U2AF2
2
U2AF2 [nucleoplasm]
(R-HSA-71987)
5OHK15,276-U2AF2 [nucleoplasm]
(R-HSA-9630011)
0.629
3
UniProt:O95822-2 MLYCD
2
MLYCD(40-493) [cytosol]
(R-HSA-9033089)
MLYCD(40-493) [peroxisomal matrix]
(R-HSA-2291936)
0.601
4
UniProt:P50221 MEOX1
0.601
4
UniProt:P37173 TGFBR2
9
TGFBR2 [plasma membrane]
(R-HSA-170842)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
6
UniProt:Q92876 KLK6
0.556
3
UniProt:P02649 APOE
10
APOE [endoplasmic reticulum lumen]
(R-HSA-6784908)
p-APOE [endoplasmic reticulum lumen]
(R-HSA-8956980)
APOE [extracellular region]
(R-HSA-174646)
APOE [endocytic vesicle lumen]
(R-HSA-3221641)
APOE-4 [extracellular region]
(R-HSA-9711070)
APOE [plasma membrane]
(R-HSA-174615)
APOE [clathrin-coated endocytic vesicle membrane]
(R-HSA-174651)
APOE [endosome membrane]
(R-HSA-174766)
APOE [endosome lumen]
(R-HSA-174804)
APOE [early endosome]
(R-HSA-2429687)
0.556
3
UniProt:P27797 CALR
6
CALR [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
0.556
3
UniProt:Q8TDX7 NEK7
2
NEK7 [cytosol]
(R-HSA-2530599)
p-S195-NEK7 [cytosol]
(R-HSA-2984246)
0.556
3
UniProt:Q6FHY5 Q6FHY5
0.556
6
UniProt:P36957 DLST
5
Lipo-K110-DLST [mitochondrial matrix]
(R-HSA-69993)
SuccinyllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853502)
LipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9853485)
DLST [mitochondrial matrix]
(R-HSA-6792574)
GlutaryllipoH2-K110-DLST [mitochondrial matrix]
(R-HSA-9858581)
0.556
3
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.527
2
UniProt:Q96I25 RBM17
1
RBM17 [nucleoplasm]
(R-HSA-8865891)
0.527
3
UniProt:Q12906 ILF3
3
ILF3 [nucleoplasm]
(R-HSA-9760401)
ILF3 [cytosol]
(R-HSA-450564)
p-T188,T315-ILF3 [cytosol]
(R-HSA-9836381)
0.519
2
UniProt:O15042 U2SURP
1
U2SURP [nucleoplasm]
(R-HSA-8865950)
0.508
2
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