TPR(2-629)-p-7Y-ALK(1058-1620) fusion [cytosol]

Stable Identifier
R-HSA-9711958
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Nucleoprotein TPR, TPR_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
24736082 A novel fusion of TPR and ALK in lung adenocarcinoma

Kim, RN, Choi, YL, Mann, DL, Mao, M, Pandy, K, Stahl, JA, Lira, ME, Choi, SJ, Hong, M, Song, JY, Han, J, Zheng, Z, Peckham, HE, Kim, J

J Thorac Oncol 2014
External Reference Information
External Reference
UniProt:P12270 TPR
Gene Names
TPR
Chain
initiator methionine:, chain:2-2363
Reference Genes
BioGPS Gene:7175 TPR
COSMIC (genes):TPR TPR
CTD Gene:7175 TPR
dbSNP Gene:7175 TPR
ENSEMBL:ENSG00000047410 TPR
HGNC:12017 TPR
KEGG:hsa:7175 TPR
Monarch:7175 TPR
NCBI Gene:7175 TPR
OMIM:189940 TPR
UCSC:P12270 TPR
Reference Transcript
Other Identifiers
11727481_at
11727482_a_at
11727483_a_at
11727484_a_at
11727485_at
1557227_PM_s_at
1557227_s_at
16697299
201730_PM_s_at
201730_s_at
201731_PM_s_at
201731_s_at
215220_PM_s_at
215220_s_at
228709_PM_at
228709_at
2448233
2448234
2448235
2448236
2448237
2448238
2448239
2448240
2448241
2448244
2448247
2448248
2448249
2448251
2448252
2448254
2448255
2448256
2448257
2448259
2448260
2448261
2448262
2448264
2448265
2448266
2448267
2448268
2448269
2448270
2448271
2448272
2448273
2448274
2448275
2448276
2448277
2448278
2448279
2448280
2448281
2448282
2448283
2448284
2448285
2448286
2448287
2448288
2448289
2448290
2448291
2448292
2448293
2448294
2448295
2448296
2448297
2448298
2448300
2448301
2448302
2448303
2448305
2448307
2448308
2448309
2448310
2448311
2448312
2448313
2448314
2448315
2448316
2448317
2448318
2448319
2448320
2448321
2448322
421_at
7175
75951_r_at
7922912
A_23_P45875
A_24_P179611
A_33_P3361771
GE59926
GE903194
GO:0000122
GO:0000775
GO:0000776
GO:0003682
GO:0003723
GO:0003729
GO:0005198
GO:0005515
GO:0005634
GO:0005635
GO:0005643
GO:0005654
GO:0005694
GO:0005737
GO:0005819
GO:0005856
GO:0005868
GO:0006355
GO:0006404
GO:0006405
GO:0006406
GO:0006606
GO:0006886
GO:0006913
GO:0006999
GO:0007094
GO:0008092
GO:0010965
GO:0015031
GO:0015631
GO:0016020
GO:0017056
GO:0031072
GO:0031453
GO:0031965
GO:0031990
GO:0032880
GO:0034399
GO:0034605
GO:0035457
GO:0042307
GO:0042405
GO:0042803
GO:0043226
GO:0044615
GO:0045947
GO:0046827
GO:0046832
GO:0051019
GO:0051028
GO:0051301
GO:0070840
GO:0070849
GO:0072686
GO:0090267
GO:0090316
GO:1901673
HMNXSV003017559
Hs.169750.0.S1_3p_a_at
Hs.218791.1.A1_3p_at
Hs.306642.0.S1_3p_s_at
Hs2.433856.1.S1_3p_s_at
ILMN_1730999
PH_hs_0022811
TC01003636.hg
TC01005999.hg
X66397_at
g4507658_3p_a_at
Participates
as a component of
Other forms of this molecule
TPR M489P [nucleoplasm]
TPR L458P [nucleoplasm]
TPR(2-629)-ALK(1058-1620) fusion [cytosol]
TPR [nucleoplasm]
Modified Residues
Name
Insertion of residues 1058 to 1620 at 630 from UniProt:Q9UM73 ALK
Coordinate
630
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1278
Coordinate
1278
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1282
Coordinate
1282
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1283
Coordinate
1283
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1359
Coordinate
1359
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1507
Coordinate
1507
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1604
Coordinate
1604
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
lung adenocarcinoma DOID:3910 nonsmall cell adenocarcinoma
Cross References
RefSeq
COSMIC
ENSEMBL
OpenTargets
GeneCards
TPR
HPA
PRO
Pharos - Targets
GlyGen
Orphanet
TPR
PDB
Interactors (5)
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