Reactome | SSB [nucleoplasm]

SSB [nucleoplasm]

Stable Identifier

R-HSA-58418

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Lupus La protein, Sjogren syndrome type B antigen, SS-B, La ribonucleoprotein, La autoantigen

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P05455 SSB

Gene Names

SSB

Chain

chain:1-408

Reference Genes

BioGPS Gene:6741 SSB

COSMIC (genes):SSB SSB

CTD Gene:6741 SSB

dbSNP Gene:6741 SSB

ENSEMBL:ENSG00000138385 SSB

ENSEMBL:ENSG00000138385.16 SSB

HGNC:11316 SSB

KEGG Gene (Homo sapiens):6741 SSB

Monarch:6741 SSB

NCBI Gene:6741 SSB

OMIM:109090 SSB

UCSC:P05455 SSB

Reference Transcript

Other Identifiers

11753897_a_at

16887334

201138_PM_s_at

201138_s_at

201139_3p_s_at

201139_PM_s_at

201139_s_at

2514570

2514572

2514573

2514574

2514575

2514579

2514581

2514583

2514585

2514586

2514588

2514590

2514591

2514592

2514593

38450_at

6741

8046201

A_23_P154025

GE61275

GO:0000049

GO:0000781

GO:0001682

GO:0003676

GO:0003677

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005694

GO:0005737

GO:0005829

GO:0006396

GO:0006399

GO:0006400

GO:0006409

GO:0006913

GO:0008033

GO:0008266

GO:0008334

GO:0010494

GO:0016071

GO:0042780

GO:0043226

GO:0045727

GO:0071045

GO:0075522

GO:1903608

GO:1990825

GO:1990904

HMNXSV003007802

Hs.83715.0.S1_3p_a_at

ILMN_1672006

ILMN_2219628

PH_hs_0029718

PH_hs_0032620

TC02001007.hg

X14684_s_at

g10835066_3p_a_at

This entity regulates

Positively

RNA Polymerase III Termination and release of transcribed RNA (Homo sapiens)

Cross References

RefSeq

NP_003133.1, NP_001281074.1

OpenTargets

ENSG00000138385

GeneCards

P05455

HPA

ENSG00000138385-SSB

Ensembl

ENSP00000386636, ENST00000409333, ENST00000260956, ENSG00000138385, ENSP00000260956

PRO

P05455

Pharos - Targets

P05455

PDB

1OWX, 1ZH5, 1YTY, 1S79, 2VOO, 1S7A, 2VOP, 2VON, 2VOD

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.623	3
UniProt:Q99IB8-PRO_0000045599			0.564	2
UniProt:O96000 NDUFB10	1	NDUFB10 [mitochondrial inner membrane] (R-HSA-60194)	0.556	3
IntAct:EBI-25917276 CCSB			0.556	3
UniProt:P54652 HSPA2	2	HSPA2 [cytosol] (R-HSA-3371408) HSPA2 [nucleoplasm] (R-HSA-912480)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q8WZA2 RAPGEF4	1	RAPGEF4 [plasma membrane] (R-HSA-3008666)	0.556	3
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.527	2
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.508	2