p-4S-UPF1 [cytosol]

Stable Identifier
R-HSA-927856
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
UPF1 Phosphorylated at Serines 1084, 1089,1107, 1127, Regulator of nonsense transcripts 1, RENT1_HUMAN, UPF1
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q92900 UPF1
Gene Names
UPF1, KIAA0221, RENT1
Chain
chain:1-1129
Reference Genes
BioGPS Gene:5976 UPF1
COSMIC (genes):UPF1 UPF1
CTD Gene:5976 UPF1
dbSNP Gene:5976 UPF1
ENSEMBL:ENSG00000005007 UPF1
HGNC:9962 UPF1
KEGG Gene (Homo sapiens):5976 UPF1
Monarch:5976 UPF1
NCBI Gene:5976 UPF1
OMIM:601430 UPF1
UCSC:Q92900 UPF1
Reference Transcript
Other Identifiers
0006200500
11717322_a_at
11754616_a_at
11754617_s_at
16859874
19587
20857
208947_s_at
211168_s_at
2GJK
2GK6
2GK7
2IYK
2WJV
2WJY
2XZO
2XZP
3825384
3825385
3825386
3825393
3825394
3825395
3825396
3825398
3825400
3825401
3825402
3825404
3825405
3825406
3825408
3825409
3825411
3825412
3825414
3825416
3825417
3825419
3825420
3825421
3825423
3825424
3825426
3825427
3825428
39404_s_at
5976
6EJ5
8027074
A0A024R7L5
A0A024R7L8
A_24_P194154
AAB94785
AAC26788
AAC50771
AAC51140
AAH39817
AC003972
AF074016
AZI15648
BAA19664
BC039817
CCDS12386
CCDS74315
CH471106
D86988
D86988_at
EAW84738
EAW84739
EAW84740
EAW84741
EAW84742
ENSG00000005007
ENSP00000262803
ENSP00000470142
ENST00000262803
ENST00000262803.9
ENST00000599848
ENST00000599848.5
EntrezGene:5976
EntrezGene:UPF1
g1633577_3p_a_at
g1944406_3p_a_at
GE62804
GO:0000166
GO:0000184
GO:0000228
GO:0000294
GO:0000784
GO:0000785
GO:0000932
GO:0000956
GO:0003674
GO:0003677
GO:0003682
GO:0003723
GO:0003724
GO:0004386
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006259
GO:0006260
GO:0006281
GO:0006406
GO:0006412
GO:0006449
GO:0006810
GO:0006913
GO:0006950
GO:0007049
GO:0008150
GO:0008270
GO:0009048
GO:0009056
GO:0009058
GO:0015031
GO:0016032
GO:0016787
GO:0016887
GO:0032201
GO:0032204
GO:0032991
GO:0034641
GO:0034655
GO:0035145
GO:0042162
GO:0042592
GO:0043167
GO:0043226
GO:0044403
GO:0044530
GO:0044770
GO:0046872
GO:0051276
GO:0061014
GO:0061158
GO:0071044
GO:0071222
GO:0071347
HGNC:9962
HPA019587
HPA020857
ILMN_1688011
IPR006935
IPR018999
IPR027417
IPR040812
IPR041677
IPR041679
MH183201
MIM:601430
NM_001297549
NM_002911
NP_001284478
NP_002902
PF04851
PF09416
PF13086
PF13087
PF18141
PH_hs_0024447
TC19000365.hg
U59323
U65533
U65533_s_at
UPF1
UPF1-201
UPF1-207
UPI0000001C89
UPI00001344ED
XM_017027105
XM_017027106
XP_016882594
XP_016882595
Participant Of
hasComponent
This entity regulates
Positively
Other forms of this molecule
UPF1 [cytosol]
Inferred To
phospho-p-4S-UPF1 [cytosol] (Bos taurus)
phospho-p-4S-UPF1 [cytosol] (Caenorhabditis elegans)
phospho-p-4S-UPF1 [cytosol] (Canis familiaris)
phospho-p-4S-UPF1 [cytosol] (Danio rerio)
phospho-p-4S-UPF1 [cytosol] (Dictyostelium discoideum)
phospho-p-4S-UPF1 [cytosol] (Drosophila melanogaster)
phospho-p-4S-UPF1 [cytosol] (Gallus gallus)
phospho-p-4S-UPF1 [cytosol] (Mus musculus)
phospho-p-4S-UPF1 [cytosol] (Plasmodium falciparum)
phospho-p-4S-UPF1 [cytosol] (Rattus norvegicus)
phospho-p-4S-UPF1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-4S-UPF1 [cytosol] (Schizosaccharomyces pombe)
phospho-p-4S-UPF1 [cytosol] (Sus scrofa)
phospho-p-4S-UPF1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 1089
Coordinate
1089
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1107
Coordinate
1107
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1084
Coordinate
1084
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1127
Coordinate
1127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
PDB
Interactors (23)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9HAU5 UPF2  1 0.953 29
 UniProt:Q9BZI7 UPF3B  2 0.848 10
 UniProt:Q9NPI6 DCP1A  1 0.783 13
 UniProt:Q96Q15 SMG1  1 0.758 7
 UniProt:O95793 STAU1      0.714 5
 UniProt:O15234 CASC3  2 0.698 5
 UniProt:Q9Y5S9 RBM8A  2 0.643 3
 UniProt:Q8IU60 DCP2  1 0.641 3
 UniProt:Q9NPJ4 PNRC2  1 0.616 9
 UniProt:Q09161 NCBP1  2 0.597 4
 UniProt:Q8IYD1 GSPT2  1 0.576 3
 UniProt:Q9UN81 LORF1      0.576 6
 UniProt:Q9H1J1 UPF3A  1 0.564 4
 UniProt:P11940 PABPC1  1 0.527 3
 UniProt:P03496 NS  2 0.527 2
 UniProt:Q96AP0 ACD  1 0.524 3
 UniProt:O14746 TERT  1 0.524 3
 UniProt:P55265 ADAR  1 0.524 3
 UniProt:Q92540 SMG7  1 0.499 3
 UniProt:Q14493 SLBP  2 0.499 3
 UniProt:Q9BZI7-2 UPF3B      0.488 2
 UniProt:P22087 FBL  1 0.462 4
 UniProt:P06730 EIF4E  1 0.462 3