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ILF3 binds CDH11 gene promoter
Stable Identifier
R-HSA-9760652
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Regulation of Homotypic Cell-Cell Adhesion (Homo sapiens)
Regulation of Expression and Function of Type II Classical Cadherins (Homo sapiens)
Regulation of CDH11 Expression and Function (Homo sapiens)
Regulation of CDH11 gene transcription (Homo sapiens)
ILF3 binds CDH11 gene promoter (Homo sapiens)
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ILF3 (Interleukin enhancer-binding factor 3) binds to two out of four putative ILF3 binding sites in the CDH11 gene promoter, at positions -2982 to -2978, and -2602 to -2598 upstream from the start site. ILF3 binding directly stimulates CDH11 gene transcription (Zhang et al. 2011).
Literature References
PubMed ID
Title
Journal
Year
29296180
Interleukin enhancer-binding factor 3 and HOXC8 co-activate cadherin 11 transcription to promote breast cancer cells proliferation and migration
Gong, C
,
Li, Y
,
Zhang, M
,
Kai, Y
,
Zhang, J
,
Yang, C
,
Zhang, Y
,
Zou, J
,
Liu, H
,
Xu, S
Oncotarget
2017
Participants
Input
CDH11 gene [nucleoplasm]
(Homo sapiens)
ILF3 [nucleoplasm]
(Homo sapiens)
Output
ILF3:CDH11 gene [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Regulation of CDH11 gene transcription (Homo sapiens)
Authored
Orlic-Milacic, M (2022-06-02)
Reviewed
Brasch, J (2023-04-18)
Created
Orlic-Milacic, M (2021-12-20)
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