Reactome | RPS13 [nucleoplasm]

RPS13 [nucleoplasm]

Stable Identifier

R-HSA-6791198

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S ribosomal protein S13, RS13_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62277 RPS13

Gene Names

RPS13

Chain

initiator methionine:1, chain:2-151

Reference Genes

BioGPS Gene:6207 RPS13

COSMIC (genes):RPS13 RPS13

CTD Gene:6207 RPS13

dbSNP Gene:6207 RPS13

ENSEMBL:ENSG00000110700 RPS13

HGNC:10386 RPS13

KEGG Gene (Homo sapiens):6207 RPS13

Monarch:6207 RPS13

NCBI Gene:6207 RPS13

OMIM:180476 RPS13

UCSC:P62277 RPS13

Reference Transcript

RefSeq:NM_001017.2 RPS13

Other Identifiers

16736211

18671365

18671367

18671368

18671370

18671373

18671375

200018_PM_at

200018_at

2413009

33619_at

3364723

3364724

3364728

3364729

3364731

3364736

3364739

6207

7893298

7893573

7893850

7894916

7895780

7895972

7896446

7946812

ADDON000110.hg

A_21_P0014671

A_24_P372608

A_32_P86028

GE61226

GO:0000184

GO:0002181

GO:0003674

GO:0003723

GO:0003729

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006412

GO:0006413

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0009056

GO:0009058

GO:0014069

GO:0015031

GO:0016020

GO:0019083

GO:0019843

GO:0022626

GO:0022627

GO:0032991

GO:0033119

GO:0034641

GO:0034655

GO:0043226

GO:0044403

GO:0048027

GO:0070062

GO:0070181

PH_hs_0030325

TC11003072.hg

TC11003475.hg

g4506684_3p_at

g4506684_3p_s_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

This entity regulates

Positively

30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Homo sapiens)

Other forms of this molecule

RPS13 [cytosol]

Inferred To

rps13 [nucleoplasm] (Danio rerio)

rps13 [nucleoplasm] (Dictyostelium discoideum)

rps13 [nucleoplasm] (Schizosaccharomyces pombe)

rps-13 [nucleoplasm] (Caenorhabditis elegans)

Rps13 [nucleoplasm] (Mus musculus)

Rps13 [nucleoplasm] (Rattus norvegicus)

RpS13 [nucleoplasm] (Drosophila melanogaster)

RPS13 [nucleoplasm] (Bos taurus)

RPS13 [nucleoplasm] (Canis familiaris)

RPS13 [nucleoplasm] (Plasmodium falciparum)

RPS13 [nucleoplasm] (Saccharomyces cerevisiae)

RPS13 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001008.1

OpenTargets

ENSG00000110700

HPA

ENSG00000110700-RPS13

GeneCards

P62277

Ensembl

ENSP00000435777, ENSG00000110700, ENST00000525634

PRO

P62277

Pharos - Targets

P62277

GlyGen

P62277

PDB

7MQA, 6YBW, 6ZOK, 6ZLW, 6G5H, 6ZM7, 6OM0, 6G5I, 6ZON, 6OM7, 4V6X, 6OLZ, 6ZP4, 5FLX, 6FEC, 7K5I, 5A2Q, 7A09, 5AJ0, 6G4S, 6OLE, 6G51, 6YBD, 6G18, 6ZVH, 6G4W, 6XA1, 5OA3, 7MQ8, 6OLG, 6OLF, 6G53, 6ZVJ, 5T2C, 6ZOJ, 6Y2L, 7MQ9, 5LKS, 6OLI, 6ZN5, 6QZP, 6IP5, 6ZMW, 6ZXH, 6IP6, 6ZUO, 6Y57, 6Z6L, 6ZV6, 6Z6N, 6IP8, 6Z6M, 6ZME, 6ZXD, 6ZMI, 6ZXF, 4UG0, 6Y0G, 6ZXE, 6ZMO, 5VYC, 6ZMT, 6ZXG

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.59	3
UniProt:Q99558 MAP3K14	5	Active NIK [cytosol] (R-HSA-5607646) MAP3K14 [cytosol] (R-HSA-168189) p-MAP3K14 [cytosol] (R-HSA-168187) K48polyUb-NIK [cytosol] (R-HSA-5668525) p-T559-MAP3K14 [cytosol] (R-HSA-5668531)	0.564	3
UniProt:Q53EL6 PDCD4	1	PDCD4 [cytosol] (R-HSA-5432887)	0.527	2
UniProt:Q8NAV1 PRPF38A	1	PRPF38A [nucleoplasm] (R-HSA-8867897)	0.508	2
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.495	2
UniProt:Q92731 ESR2	5	PalmS-ESR2 [cytosol] (R-HSA-9020979) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.462	2

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