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Go!
Autophagosome
Categories
Cell element
Curator
Steve Jupe
Designer
Cristoffer Sevilla
Description
An autophagosome is a spherical structure with double layer membranes. It is the key structure in macroautophagy, the intracellular degradation system for cytoplasmic contents and also for invading microorganisms
Icon preview
SVG
PNG
EMF
Locations in the PathwayBrowser
Autophagy (R-HSA-9612973)
Organelle biogenesis and maintenance (R-HSA-1852241)
Vesicle-mediated transport (R-HSA-5653656)
Entries for Autophagosome
AMBRA1 [cytosol]
ATG12 [cytosol]
ATG12 [phagocytic vesicle membrane]
ATG14 [cytosol]
ATG14 [endoplasmic reticulum membrane]
ATG14 [phagophore assembly site membrane]
ATG16L1 [cytosol]
ATG4B [cytosol]
ATG5 [cytosol]
ATG5 [phagocytic vesicle membrane]
ATG9A [phagophore assembly site membrane]
ATG9B [phagophore assembly site membrane]
ATP13A2 [lysosomal lumen]
BECN1 [cytosol]
CLN3 [Golgi membrane]
GABARAP [autophagosome membrane]
GABARAP [cytosol]
GABARAP(1-117) [cytosol]
GABARAPL1 [autophagosome membrane]
GABARAPL1 [cytosol]
GABARAPL1(1-117) [cytosol]
GABARAPL2 [autophagosome membrane]
GABARAPL2 [cytosol]
GABARAPL2(1-117) [cytosol]
GGC-RAB23 [cytosol]
GGC-RAB24 [cytosol]
GlyK130-ATG5 [cytosol]
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
HSPA8 [cytosol]
HSPA8 [extracellular region]
HSPA8 [ficolin-1-rich granule lumen]
HSPA8 [late endosome lumen]
HSPA8 [lysosomal lumen]
HSPA8 [nucleoplasm]
HSPA8 [plasma membrane]
HSPA8 [secretory granule lumen]
HTT [nucleoplasm]
ISG15-K-BECN1 [cytosol]
K63polyUb-BECN1 [cytosol]
K63polyUb-STING [cytoplasmic vesicle membrane]
K63polyUb-STING [endoplasmic reticulum membrane]
K7 ub-SQSTM1 [cytosol]
MAP1LC3A [autophagosome membrane]
MAP1LC3A [cytosol]
MAP1LC3A(1-121) [cytosol]
MAP1LC3B [autophagosome membrane]
MAP1LC3B [cytosol]
MAP1LC3B(2-121) [cytosol]
MAP1LC3C [autophagosome membrane]
MAP1LC3C [cytosol]
MAP1LC3C(1-147) [cytosol]
Me3K561-HSPA8 [nucleoplasm]
MEFV [cytosol]
MYO6 [cytosol]
MYO6 [lysosomal membrane]
MYO6 [plasma membrane]
NBR1 [cytosol]
NBR1 [peroxisomal membrane]
NRBF2-1 [nucleoplasm]
NRBF2-2 [nucleoplasm]
OPTN [cytosol]
OPTN [Golgi membrane]
OPTN [recycling endosome membrane]
OSBPL7 [cytosol]
p-AMBRA1 [cytosol]
p-S15-BECN1 [cytosol]
p-S177-OPTN [cytosol]
p-S177-OPTN [nucleoplasm]
p-S317,467,556,638,T575-ULK1 [cytosol]
p-S326-PIP4K2B [nucleoplasm]
p-S349 SQSTM1 [cytosol]
p-S758-ULK1 [cytosol]
p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]
p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
PIK3C3 [cytosol]
PIK3C3 [phagocytic vesicle membrane]
PIK3R4 [cytosol]
PIK3R4 [phagocytic vesicle membrane]
PIP4K2A [cytosol]
PIP4K2A [nucleoplasm]
PIP4K2B [cytosol]
PIP4K2B [nucleoplasm]
PIP4K2C [cytosol]
PIP4K2C [nucleoplasm]
RAB23 [cytosol]
RAB24 [cytosol]
RAB24 [plasma membrane]
RAB24 [secretory granule membrane]
SNAP29 [azurophil granule membrane]
SNAP29 [Golgi membrane]
SNAP29 [plasma membrane]
SQSTM1 [cytosol]
SQSTM1 [nucleoplasm]
SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol]
STING [endoplasmic reticulum membrane]
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
TAX1BP1 [cytosol]
TBC1D14 [recycling endosome]
TBC1D17 [recycling endosome]
TBC1D25 [autophagosome]
TEX264 [extracellular region]
TEX264 [platelet alpha granule lumen]
TICAM1 [cytosol]
TICAM1 [endosome membrane]
TICAM1 R141* [cytosol]
TICAM1 S186L [cytosol]
TMEM173 [plasma membrane]
TMEM173 [secretory granule membrane]
TP53INP1 [nucleoplasm]
TRIM21 [cytosol]
ub K420 p-S349 SQSTM1 [cytosol]
UBQLN1 [cytosol]
UBQLN2 [cytosol]
ULK1 [cytosol]
ULK1 [mitochondrial outer membrane]
ULK1 [recycling endosome]
ULK3 [ciliary tip]
UVRAG [cytosol]
UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane]
VPS16 [endosome membrane]
VPS18 [endosome membrane]
VPS33A [endosome membrane]
VTI1A [Golgi membrane]
VTI1A [trans-Golgi network membrane]
External References
GO
0005776
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