Reactome | VPS33A [endosome membrane]

VPS33A [endosome membrane]

Stable Identifier

R-HSA-2197804

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Vacuolar protein sorting-associated protein 33A, VP33A_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96AX1 VPS33A

Gene Names

VPS33A

Chain

chain:1-596

Reference Genes

BioGPS Gene:65082 VPS33A

COSMIC (genes):VPS33A VPS33A

CTD Gene:65082 VPS33A

dbSNP Gene:65082 VPS33A

ENSEMBL:ENSG00000139719 VPS33A

ENSEMBL_homo_sapiens_GENE:ENSG00000139719.11 VPS33A

HGNC:18179 VPS33A

Monarch:65082 VPS33A

NCBI Gene:65082 VPS33A

OMIM:610034 VPS33A

UCSC:Q96AX1 VPS33A

Reference Transcript

RefSeq:NM_022916.4 VPS33A

Other Identifiers

11744159_at

16771652

204590_PM_x_at

204590_x_at

227815_PM_at

227815_at

3475540

3475541

3475542

3475544

3475546

3475547

3475548

3475549

3475550

3475551

3475552

3475553

3475555

3475556

3475557

3475558

3475559

3475560

3475564

3475566

3475570

3475571

3475572

3475574

3475575

44160_at

45693_at

65082

7967240

A_23_P36408

GE82738

GE85656

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005770

GO:0005773

GO:0005776

GO:0006886

GO:0006914

GO:0007040

GO:0008333

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0030123

GO:0030136

GO:0030154

GO:0030220

GO:0030897

GO:0031410

GO:0031902

GO:0032400

GO:0032418

GO:0033263

GO:0034058

GO:0035542

GO:0035751

GO:0043226

GO:0043473

GO:0048070

GO:0048471

GO:0048856

GO:0061024

GO:0065003

GO:0071439

GO:0097352

HMNXSV003044120

Hs.50730.0.A1_3p_at

ILMN_1662316

ILMN_1857487

PH_hs_0005527

PH_hs_0025744

TC12003287.hg

g12597662_3p_at

Participates

as a component of

HOPS Complex [endosome membrane] (Homo sapiens)

Cross References

RefSeq

NP_075067.2

OpenTargets

ENSG00000139719

HPA

ENSG00000139719-VPS33A

GeneCards

Q96AX1

Ensembl

ENST00000267199, ENSP00000267199, ENSG00000139719

PRO

Q96AX1

Pharos - Targets

Q96AX1

PDB

4BX8, 4BX9

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P2Y5 UVRAG	2	UVRAG [cytosol] (R-HSA-5668884) UVRAG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9730510)	0.564	4
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q14790 CASP8	8	CASP8(1-374) [cytosol] (R-HSA-3465404) CASP8(217-374) [mitochondrial outer membrane] (R-HSA-351869) CASP8(385-479) [mitochondrial outer membrane] (R-HSA-351828) CASP8(385-479) [cytosol] (R-HSA-76158) CASP8(375-384) [cytosol] (R-HSA-933460) CASP8(217-374) [cytosol] (R-HSA-75975) CASP8(1-216) [cytosol] (R-HSA-933456) CASP8(1-479) [cytosol] (R-HSA-57031)	0.556	3