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STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
Stable Identifier
R-HSA-6807769
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum-Golgi intermediate compartment membrane
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
NSF and SNAPs bind cis-SNARE complex (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
NSF ATPase activity dissociates cis-SNARE (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
NSF and SNAPs bind cis-SNARE complex (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE:NSF hexamer:3xSNAP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
cis-SNARE [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P56962 STX17
Gene Names
STX17
Chain
initiator methionine:, chain:2-302
Reference Genes
BioGPS Gene:55014 STX17
COSMIC (genes):STX17 STX17
CTD Gene:55014 STX17
dbSNP Gene:55014 STX17
ENSEMBL:ENSG00000136874 STX17
ENSEMBL_homo_sapiens_GENE:ENSG00000136874.11 STX17
HGNC:11432 STX17
KEGG Gene (Homo sapiens):55014 STX17
Monarch:55014 STX17
NCBI Gene:55014 STX17
OMIM:604204 STX17
UCSC:P56962 STX17
Reference Transcript
RefSeq:XM_011518820.2 STX17
RefSeq:XM_011518821.2 STX17
RefSeq:NM_017919.2 STX17
Other Identifiers
11723806_at
11723807_at
11723808_x_at
11723809_a_at
11723810_at
11723811_a_at
11723812_at
17087535
218666_PM_s_at
218666_s_at
222708_PM_s_at
222708_s_at
226655_PM_at
226655_at
226662_PM_at
226662_at
228091_PM_at
228091_at
3182020
3182021
3182022
3182024
3182025
3182030
3182034
3182038
3182040
3182043
3182045
3182046
3182047
3182048
3182049
3182050
3182051
3182052
3182053
49260_at
52768_at
55014
57663_at
58350_at
59634_at
8156861
90126_at
A_23_P169358
A_33_P3269149
GE56955
GO:0000149
GO:0000421
GO:0005484
GO:0005515
GO:0005737
GO:0005739
GO:0005773
GO:0005776
GO:0005783
GO:0005789
GO:0005793
GO:0005829
GO:0005886
GO:0006886
GO:0006887
GO:0006888
GO:0006906
GO:0006914
GO:0007030
GO:0012505
GO:0012507
GO:0016020
GO:0016192
GO:0016240
GO:0019901
GO:0019903
GO:0030134
GO:0030868
GO:0030897
GO:0031201
GO:0031410
GO:0033116
GO:0034497
GO:0043226
GO:0044233
GO:0048278
GO:0060090
GO:0061024
GO:0097111
GO:0097352
HMNXSV003003299
HMNXSV003036328
Hs.16488.1.A1_3p_at
Hs.200332.0.S1_3p_a_at
Hs.200332.1.A1_3p_x_at
Hs.200332.1.A2_3p_at
ILMN_1750896
PH_hs_0024680
PH_hs_0041076
TC09000509.hg
g8923603_3p_a_at
Participates
as a candidate of
STX5,17 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
Inferred To
Homologues of STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Saccharomyces cerevisiae)
PEP12 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Saccharomyces cerevisiae)
VAM3 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Saccharomyces cerevisiae)
pep12 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Schizosaccharomyces pombe)
syn7A [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Dictyostelium discoideum)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Bos taurus)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Canis familiaris)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Gallus gallus)
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Sus scrofa)
Stx17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Mus musculus)
Stx17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Rattus norvegicus)
Cross References
RefSeq
XP_011517122.1
,
NP_060389.2
,
XP_011517123.1
OpenTargets
ENSG00000136874
HPA
ENSG00000136874-STX17
GeneCards
P56962
Ensembl
ENST00000525640
,
ENSP00000259400
,
ENSP00000435981
,
ENSG00000136874
,
ENST00000534052
,
ENST00000259400
,
ENSP00000433484
PRO
P56962
Pharos - Targets
P56962
PDB
7BV6
,
4WY4
,
7BV4
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BV40 VAMP8
11
VAMP8 [tertiary granule membrane]
(R-HSA-6801024)
VAMP8 [plasma membrane]
(R-HSA-376365)
VAMP8 [azurophil granule membrane]
(R-HSA-6799703)
VAMP8 [specific granule membrane]
(R-HSA-6799707)
VAMP8 [recycling endosome membrane]
(R-HSA-8863891)
VAMP8 [phagocytic vesicle membrane]
(R-HSA-8863896)
VAMP8 [lysosomal membrane]
(R-HSA-432710)
VAMP8 [Golgi membrane]
(R-HSA-266201)
VAMP8 [cytoplasmic vesicle membrane]
(R-HSA-376373)
VAMP8 [secretory granule membrane]
(R-HSA-376368)
VAMP8 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869137)
0.737
11
UniProt:Q9P296 C5AR2
1
C5AR2 [plasma membrane]
(R-HSA-964798)
0.527
2
UniProt:O00161 SNAP23
5
SNAP23 [tertiary granule membrane]
(R-HSA-6806141)
SNAP23 [plasma membrane]
(R-HSA-376345)
SNAP23 [specific granule membrane]
(R-HSA-6806157)
p-S95-SNAP23 [phagocytic vesicle membrane]
(R-HSA-8863923)
SNAP23 [phagocytic vesicle membrane]
(R-HSA-8863966)
0.471
2
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