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MAP1LC3B [cytosol]
Stable Identifier
R-HSA-5205651
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Microtubule-associated proteins 1A/1B light chain 3B, MLP3B_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
ATG16L1 complex transfers LC3 from ATG3 to PE (Homo sapiens)
LC3:PE [phagophore assembly site membrane] (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Autophagosome maturation (Homo sapiens)
LC3:PE [phagophore assembly site membrane] (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3 binds ATG7 dimer (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3 de-lipidation by ATG4 (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3:PE [phagophore assembly site membrane] (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3 is cleaved by ATG4 (Homo sapiens)
LC3 family [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Selective autophagy (Homo sapiens)
Mitophagy (Homo sapiens)
PINK1-PRKN Mediated Mitophagy (Homo sapiens)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B:p-S-TBK1:p-S-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
p62 links damaged mitochondria to LC3 (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Receptor Mediated Mitophagy (Homo sapiens)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
p-S17-FUNDC1:LC3:ATG5:ATG12 [cytosol] (Homo sapiens)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
p-S17-FUNDC1:LC3 [mitochondrial outer membrane] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Pexophagy (Homo sapiens)
MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Homo sapiens)
ATM dimer:Ub-p-PEX5:SQSTM1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Homo sapiens)
ATM dimer:Ub-p-PEX5:SQSTM1:NBR1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
NBR1 binds MAP1LC3B (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
NBR1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
MAP1LC3B binds KEAP1 and SQSTM1 (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
RBX1:CUL3 dissociates from forming autophagosome (Homo sapiens)
MAP1LC3B:SESN1,2:ub K420 p-S349 SQSTM1 oligomer:ub-KEAP1 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
8b binds MAP1LC3B (Homo sapiens)
8b:MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
nsp8 binds MAP1LC3B (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
nsp8:MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Early SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Replicase and Assembly of the Replication Transcription Complex (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
nsp8 binds MAP1LC3B (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
nsp8:MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 modulates autophagy (Homo sapiens)
SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B:TUFM:M [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
MAP1LC3B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9GZQ8 MAP1LC3B
Gene Names
MAP1LC3B, MAP1ALC3
Chain
chain:1-120, propeptide:121-125
Reference Genes
BioGPS Gene:81631 MAP1LC3B
COSMIC (genes):MAP1LC3B MAP1LC3B
CTD Gene:81631 MAP1LC3B
dbSNP Gene:81631 MAP1LC3B
ENSEMBL:ENSG00000140941 MAP1LC3B
ENSEMBL_homo_sapiens_GENE:ENSG00000140941.14 MAP1LC3B
HGNC:13352 MAP1LC3B
KEGG Gene (Homo sapiens):81631 MAP1LC3B
Monarch:81631 MAP1LC3B
NCBI Gene:81631 MAP1LC3B
OMIM:609604 MAP1LC3B
UCSC:Q9GZQ8 MAP1LC3B
Reference Transcript
RefSeq:NM_022818.4 MAP1LC3B
Other Identifiers
11731632_s_at
11738983_x_at
11738984_x_at
11748422_a_at
16821697
208785_PM_s_at
208785_s_at
208786_PM_s_at
208786_s_at
239845_PM_at
239845_at
3433487
3433489
3433491
3672823
3672825
3672829
3672831
3672832
3672838
3672841
3672843
3672844
3672845
3672846
39370_at
72361_at
7959023
7997740
81631
A_14_P132519
A_24_P108005
GE61704
GE79540
GE838028
GE893037
GO:0000045
GO:0000421
GO:0000423
GO:0005515
GO:0005737
GO:0005739
GO:0005773
GO:0005776
GO:0005829
GO:0005856
GO:0005874
GO:0005929
GO:0005930
GO:0006914
GO:0006995
GO:0007005
GO:0008017
GO:0008092
GO:0008289
GO:0008429
GO:0009267
GO:0012505
GO:0016020
GO:0016236
GO:0031090
GO:0031410
GO:0031625
GO:0031966
GO:0043226
GO:0043231
GO:0097001
GO:0097352
HMNXSV003020216
Hs.224883.0.A1_3p_at
ILMN_1703244
PH_hs_0023988
TC16000674.hg
g9963772_3p_a_at
Participates
as a component of
MAP1LC3B:SESN1,2:ub K420 p-S349 SQSTM1 oligomer:ub-KEAP1 [cytosol] (Homo sapiens)
MAP1LC3B:SESN1,SESN2:ub-K420 p-S349 SQSTM1 oligomer:ub-KEAP1:CUL3:RBX1 [cytosol] (Homo sapiens)
8b:MAP1LC3B [cytosol] (Homo sapiens)
nsp8:MAP1LC3B [cytosol] (Homo sapiens)
nsp8:MAP1LC3B [cytosol] (Homo sapiens)
MAP1LC3B:TUFM:M [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
NBR1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
ATM dimer:Ub-p-PEX5:SQSTM1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
ATM dimer:Ub-p-PEX5:SQSTM1:NBR1:MAP1LC3B [peroxisomal membrane] (Homo sapiens)
MAP1LC3B:p-S-TBK1:p-S-OPTN:K63polyUb-mitochondrial proteins [mitochondrial outer membrane] (Homo sapiens)
as an input of
MAP1LC3B binds KEAP1 and SQSTM1 (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
nsp8 binds MAP1LC3B (Homo sapiens)
Enhanced autophagosome formation (Homo sapiens)
8b binds MAP1LC3B (Homo sapiens)
nsp8 binds MAP1LC3B (Homo sapiens)
SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)
NBR1 binds MAP1LC3B (Homo sapiens)
MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Homo sapiens)
MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Homo sapiens)
MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria (Homo sapiens)
as a member of
LC3 family [cytosol] (Homo sapiens)
LC3 [cytosol] (Homo sapiens)
Other forms of this molecule
MAP1LC3B [autophagosome membrane]
MAP1LC3B(2-121) [cytosol]
Inferred To
map1lc3b [cytosol]
(Danio rerio)
Map1lc3b [cytosol]
(Mus musculus)
Map1lc3b [cytosol]
(Rattus norvegicus)
Ghost homologue of MAP1LC3B [cytosol]
(Drosophila melanogaster)
Ghost homologue of MAP1LC3B [cytosol]
(Xenopus tropicalis)
atg8 [cytosol]
(Dictyostelium discoideum)
atg8 [cytosol]
(Schizosaccharomyces pombe)
ATG8 [cytosol]
(Saccharomyces cerevisiae)
MAP1LC3B [cytosol]
(Bos taurus)
MAP1LC3B [cytosol]
(Canis familiaris)
MAP1LC3B [cytosol]
(Dictyostelium discoideum)
MAP1LC3B [cytosol]
(Gallus gallus)
MAP1LC3B [cytosol]
(Plasmodium falciparum)
MAP1LC3B [cytosol]
(Sus scrofa)
Homologues of MAP1LC3B [cytosol]
(Dictyostelium discoideum)
lgg-2 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_073729.1
OpenTargets
ENSG00000140941
GeneCards
Q9GZQ8
HPA
ENSG00000140941-MAP1LC3B
Ensembl
ENSG00000140941
,
ENSP00000268607
,
ENST00000650688
,
ENST00000268607
,
ENSP00000498476
PRO
Q9GZQ8
Pharos - Targets
Q9GZQ8
PDB
2ZJD
,
5XAE
,
3X0W
,
5V4K
,
5MS6
,
7ELG
,
6J04
,
4WAA
,
3VTU
,
5XAD
,
3WAO
,
6LAN
,
5DCN
,
3VTV
,
5GMV
,
3VTW
,
2N9X
,
5MS2
,
1V49
,
5MS5
,
5D94
,
5XAC
,
2LUE
,
5W9A
Interactors (73)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13501 SQSTM1
7
SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711967)
SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711954)
K7 ub-SQSTM1 [cytosol]
(R-HSA-9759088)
p-S349 SQSTM1 [cytosol]
(R-HSA-9766524)
ub K420 p-S349 SQSTM1 [cytosol]
(R-HSA-9766536)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
SQSTM1 [cytosol]
(R-HSA-193937)
0.978
31
UniProt:Q9Y4P1 ATG4B
1
ATG4B [cytosol]
(R-HSA-5671858)
0.952
15
UniProt:Q8WVZ9 KBTBD7
1
KBTBD7 [cytosol]
(R-HSA-5658415)
0.838
7
UniProt:Q9NT62 ATG3
8
ATG3 [cytosol]
(R-HSA-5671860)
CysO264-ATG3-MAP1LC3A [cytosol]
(R-HSA-9819371)
CysO264-ATG3-GABARAP [cytosol]
(R-HSA-9819379)
CysO264-ATG3-GABARAPL3 [cytosol]
(R-HSA-5683569)
CysO264-ATG3-MAP1LC3B [cytosol]
(R-HSA-9819365)
CysO264-ATG3-GABARAPL1 [cytosol]
(R-HSA-9819381)
CysO264-ATG3-MAP1LC3C [cytosol]
(R-HSA-9819377)
CysO264-ATG3-GABARAPL2 [cytosol]
(R-HSA-9819376)
0.8
8
UniProt:Q8IVP5 FUNDC1
4
p-S17-FUNDC1 [mitochondrial outer membrane]
(R-HSA-8948140)
p-S13,Y18-FUNDC1 [mitochondrial outer membrane]
(R-HSA-8934915)
FUNDC1 [mitochondrial outer membrane]
(R-HSA-8934922)
p-S13-FUNDC1 [mitochondrial outer membrane]
(R-HSA-8934910)
0.779
8
UniProt:Q14596 NBR1
2
NBR1 [peroxisomal membrane]
(R-HSA-9665177)
NBR1 [cytosol]
(R-HSA-9665180)
0.766
9
UniProt:Q9BQS8 FYCO1
0.757
9
UniProt:Q86V97 KBTBD6
1
KBTBD6 [cytosol]
(R-HSA-8863221)
0.747
6
UniProt:O95352 ATG7
14
ATG7 [secretory granule lumen]
(R-HSA-6801316)
ATG7 [extracellular region]
(R-HSA-6806451)
ATG7 [ficolin-1-rich granule lumen]
(R-HSA-6801293)
ATG7(1-693)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802272)
ATG7(1-693)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802517)
CysO572-ATG7-MAP1LC3B [cytosol]
(R-HSA-9820410)
CysO572-ATG7-GARABAPL2 [cytosol]
(R-HSA-9820413)
CysO572-ATG7-GARABAP [cytosol]
(R-HSA-9820417)
CysO572-ATG7-GARABAPL1 [cytosol]
(R-HSA-9820406)
CysO572-ATG7-MAP1LC3C [cytosol]
(R-HSA-9820407)
CysO572-ATG7-MAP1LC3A [cytosol]
(R-HSA-9820421)
CysO572-ATG7-GARABAPL3 [cytosol]
(R-HSA-9820420)
CysO572-ATG7 [cytosol]
(R-HSA-5683584)
ATG7 [cytosol]
(R-HSA-947867)
0.743
7
UniProt:O75143 ATG13
3
ATG13 [cytosol]
(R-HSA-5333624)
p-ATG13 [cytosol]
(R-HSA-5675831)
p-ATG13 [endoplasmic reticulum membrane]
(R-HSA-8948049)
0.734
5
UniProt:P46821 MAP1B
1
MAP1B(2-2206) [cytosol]
(R-HSA-9836954)
0.725
8
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.718
6
UniProt:Q8IZQ1 WDFY3
0.71
6
UniProt:Q64337
5
K7 ub-SQSTM1 [cytosol]
(R-MMU-9759088)
phospho-p-S349 SQSTM1 [cytosol]
(R-MMU-9766524)
phospho-ub K420 p-S349 SQSTM1 [cytosol]
(R-MMU-9766536)
SQSTM1 [nucleoplasm]
(R-MMU-210961)
SQSTM1 [cytosol]
(R-MMU-193937)
0.698
6
UniProt:Q13043 STK4
4
STK4(1-487) [cytosol]
(R-HSA-201627)
p-T183-STK4(1-326) [cytosol]
(R-HSA-2028682)
p-T183-STK4(1-487) [cytosol]
(R-HSA-2028258)
STK4(327-487) [cytosol]
(R-HSA-2028668)
0.688
8
UniProt:P20700 LMNB1
8
LMNB1 [nucleoplasm]
(R-HSA-264867)
LMNB1(1-231) [nuclear envelope]
(R-HSA-352244)
LMNB1(232-586) [nuclear envelope]
(R-HSA-352248)
LMNB1 [cytosol]
(R-HSA-2995384)
p-S395, S405-LMNB1 [nucleoplasm]
(R-HSA-5228738)
p-S23, S395, S405-LMNB1 [nucleoplasm]
(R-HSA-5229018)
LMNB1(2-586) [nuclear envelope]
(R-HSA-912402)
p-S23,S393-LMNB1 [nucleoplasm]
(R-HSA-8868341)
0.675
14
UniProt:Q9Y383 LC7L2
0.667
3
UniProt:Q9BQD3 KXDL1
0.666
4
UniProt:Q15025 TNIP1
1
TNIP1 [cytosol]
(R-HSA-5690853)
0.666
4
UniProt:O75665 OFD1
1
OFD1 [cytosol]
(R-HSA-380318)
0.664
7
UniProt:Q8WZA9 IRGQ
0.659
4
UniProt:O75385 ULK1
7
ULK1 [recycling endosome]
(R-HSA-8854761)
p-S758-ULK1 [cytosol]
(R-HSA-5672131)
p-S317,467,556,638,T575-ULK1 [cytosol]
(R-HSA-5673747)
p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]
(R-HSA-5675858)
p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
(R-HSA-8948047)
ULK1 [cytosol]
(R-HSA-1632847)
ULK1 [mitochondrial outer membrane]
(R-HSA-8948145)
0.656
3
UniProt:P78559 MAP1A
0.643
7
UniProt:P46934 NEDD4
1
NEDD4 [cytosol]
(R-HSA-975992)
0.623
2
UniProt:Q9UH03 SEPT3
0.618
3
UniProt:Q9Z2F7
1
Bnip3l [mitochondrial outer membrane]
(R-MMU-6798001)
0.611
5
UniProt:P35222 CTNNB1
20
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
pT41,S45-CTNNB1 S37A [cytosol]
(R-HSA-4839619)
pT41,S45-CTNNB1 S37Y [cytosol]
(R-HSA-9663978)
pT41,S45-CTNNB1 S37C [cytosol]
(R-HSA-4839617)
pS37,T41,S45-CTNNB1 S33A [cytosol]
(R-HSA-9663976)
pS37,T41,S45-CTNNB1 S33T [cytosol]
(R-HSA-9663977)
pS37,T41,S45-CTNNB1 S33C [cytosol]
(R-HSA-4839630)
pS37,T41,S45-CTNNB1 S33F [cytosol]
(R-HSA-4839628)
pS37,T41,S45-CTNNB1 S33P [cytosol]
(R-HSA-4839626)
pS37,T41,S45-CTNNB1 S33Y [cytosol]
(R-HSA-4839625)
pS45-CTNNB1 T41N [cytosol]
(R-HSA-9663980)
pS45-CTNNB1 T41A [cytosol]
(R-HSA-4836868)
pS45-CTNNB1 T41I [cytosol]
(R-HSA-4839612)
0.602
5
UniProt:Q9UPU7 TBD2B
0.591
3
UniProt:Q13188 STK3
4
p-T180-STK3(1-322) [cytosol]
(R-HSA-2028696)
STK3(323-491) [cytosol]
(R-HSA-2028684)
STK3(1-491) [cytosol]
(R-HSA-2028280)
p-T180-STK3(1-491) [cytosol]
(R-HSA-2028274)
0.591
5
UniProt:Q8WWW0 RASF5
0.591
5
UniProt:Q8WZ42 TTN
2
TTN [extracellular region]
(R-HSA-350729)
TTN [cytosol]
(R-HSA-350726)
0.59
2
UniProt:Q8NC44 RETR2
0.573
2
UniProt:Q92609 TBCD5
0.571
2
UniProt:Q8NI08 NCOA7
0.571
2
UniProt:P51587 BRCA2
20
BRCA2 D2983Ffs*34 [cytosol]
(R-HSA-9709538)
BRCA2 K2555* [cytosol]
(R-HSA-9711337)
BRCA2 N2553Tfs*95 [cytosol]
(R-HSA-9712872)
BRCA2 T2685Hfs*9 [cytosol]
(R-HSA-9712879)
BRCA2 K2674Rfs*2 [cytosol]
(R-HSA-9712610)
BRCA2 S3231* [cytosol]
(R-HSA-9711458)
BRCA2 I2675Dfs*6 [cytosol]
(R-HSA-9712869)
BRCA2 R2625* [cytosol]
(R-HSA-9711482)
BRCA2 E3071* [cytosol]
(R-HSA-9711354)
BRCA2 V2716Wfs*17 [cytosol]
(R-HSA-9712761)
BRCA2 W2586* [cytosol]
(R-HSA-9711487)
BRCA2 P2767Lfs*10 [cytosol]
(R-HSA-9712509)
BRCA2 K3032* [cytosol]
(R-HSA-9711485)
BRCA2 S2835* [cytosol]
(R-HSA-9711345)
BRCA2 Y3006* [cytosol]
(R-HSA-9711222)
BRCA2 L2926* [cytosol]
(R-HSA-9711348)
BRCA2 R3128* [cytosol]
(R-HSA-9711177)
BRCA2 E2599* [cytosol]
(R-HSA-9711304)
BRCA2 E2571* [cytosol]
(R-HSA-9711560)
BRCA2 Y2977* [cytosol]
(R-HSA-9711182)
0.558
2
UniProt:P40344
8
ATG3 [cytosol]
(R-SCE-5671860)
CysO264-ATG3-MAP1LC3A [cytosol]
(R-SCE-9819371)
CysO264-ATG3-GABARAP [cytosol]
(R-SCE-9819379)
CysO264-ATG3-GABARAPL2 [cytosol]
(R-SCE-9819376)
CysO264-ATG3-MAP1LC3C [cytosol]
(R-SCE-9819377)
CysO264-ATG3-GABARAPL1 [cytosol]
(R-SCE-9819381)
CysO264-ATG3-MAP1LC3B [cytosol]
(R-SCE-9819365)
CysO264-ATG3-GABARAPL3 [cytosol]
(R-SCE-5683569)
0.558
2
UniProt:P38862
12
ATG7 [cytosol]
(R-SCE-947867)
ATG7 [cytosol]
(R-SCE-5683584)
ATG7 [cytosol]
(R-SCE-9820420)
ATG7 [cytosol]
(R-SCE-9820421)
ATG7 [cytosol]
(R-SCE-9820407)
ATG7 [cytosol]
(R-SCE-9820406)
ATG7 [cytosol]
(R-SCE-9820417)
ATG7 [cytosol]
(R-SCE-9820413)
ATG7 [cytosol]
(R-SCE-9820410)
ATG7 [ficolin-1-rich granule lumen]
(R-SCE-6801293)
ATG7 [extracellular region]
(R-SCE-6806451)
ATG7 [secretory granule lumen]
(R-SCE-6801316)
0.558
2
UniProt:P22607 FGFR3
20
FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane]
(R-HSA-8853144)
FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]
(R-HSA-8853131)
FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane]
(R-HSA-8853152)
FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]
(R-HSA-8853124)
FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane]
(R-HSA-8853125)
FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
(R-HSA-8853127)
FGFR3 K650T [plasma membrane]
(R-HSA-1614411)
FGFR3 K650N [plasma membrane]
(R-HSA-1614406)
FGFR3 K650M [plasma membrane]
(R-HSA-1614402)
FGFR3 K650Q [plasma membrane]
(R-HSA-1614410)
FGFR3 A391E [plasma membrane]
(R-HSA-1614390)
FGFR3 K650E [plasma membrane]
(R-HSA-1614400)
FGFR3 G380R [plasma membrane]
(R-HSA-1614398)
FGFR3 G382D [plasma membrane]
(R-HSA-2018740)
FGFR3 805fs*141 [plasma membrane]
(R-HSA-1614387)
FGFR3 [plasma membrane]
(R-HSA-2038357)
FGFR3 S371C [plasma membrane]
(R-HSA-1614421)
FGFR3 Y373C [plasma membrane]
(R-HSA-1614424)
FGFR3 G370C [plasma membrane]
(R-HSA-1614394)
FGFR3 R248C [plasma membrane]
(R-HSA-1614419)
0.556
3
UniProt:P28329-3 P283293
0.556
3
UniProt:O14576-2 O145762
0.556
3
UniProt:Q9BXM7 PINK1
5
p-S228,S402-PINK1 [mitochondrial outer membrane]
(R-HSA-9834051)
PINK1 [mitochondrial outer membrane]
(R-HSA-5205653)
PINK1 [mitochondrial intermembrane space]
(R-HSA-5205671)
PINK1 [cytosol]
(R-HSA-5205637)
PINK1(111-581) [mitochondrial intermembrane space]
(R-HSA-5205628)
0.556
3
UniProt:P0DMV8 HSPA1A
4
HSPA1A [nucleoplasm]
(R-HSA-6792605)
HSPA1A [extracellular region]
(R-HSA-6805872)
HSPA1A [ficolin-1-rich granule lumen]
(R-HSA-6801496)
HSPA1A [cytosol]
(R-HSA-6792602)
0.556
3
UniProt:O60260-5 PRKN
0.556
3
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P28799 GRN
2
GRN [azurophil granule lumen]
(R-HSA-6799168)
GRN [extracellular region]
(R-HSA-6806217)
0.556
3
UniProt:Q14696 MESD
0.556
3
UniProt:P05386 RPLP1
1
RPLP1 [cytosol]
(R-HSA-72398)
0.547
2
UniProt:Q15424 SAFB
3
SAFB [nucleoplasm]
(R-HSA-4085379)
polySUMO2,3-K231,K294-SAFB [nucleoplasm]
(R-HSA-4085357)
monoSUMO1-K231,K294-SAFB [nucleoplasm]
(R-HSA-4085343)
0.547
3
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.544
2
UniProt:O00410 IPO5
1
IPO5 [nucleoplasm]
(R-HSA-192675)
0.544
2
UniProt:Q9GZZ9 UBA5
1
UBA5 [cytosol]
(R-HSA-947700)
0.544
2
UniProt:Q9NS23 RASF1
0.544
2
UniProt:Q8TC07 TBC1D15
1
TBC1D15 [cytosol]
(R-HSA-8854150)
0.544
2
UniProt:Q9UHD2 TBK1
5
pS-172,K48polyUb-TBK1 [cytosol]
(R-HSA-3249397)
p-TBK1 [cytosol]
(R-HSA-9008705)
K63polyUb-K30,K401-TBK1 [cytosol]
(R-HSA-9730430)
TBK1 [cytosol]
(R-HSA-166267)
p-S172-TBK1 [cytosol]
(R-HSA-168379)
0.544
2
UniProt:O95210 STBD1
3
STBD1 [ficolin-1-rich granule membrane]
(R-HSA-6801519)
STBD1 [plasma membrane]
(R-HSA-6801561)
STBD1 [tertiary granule membrane]
(R-HSA-6801484)
0.544
2
UniProt:Q2TAZ0 ATG2A
0.544
2
UniProt:Q8TD19 NEK9
3
p-S29,T210,T333,S750,S869-NEK9 [cytosol]
(R-HSA-2984225)
p-T333-NEK9 [cytosol]
(R-HSA-2530600)
p-S29,T333,S750,S869-NEK9 [cytosol]
(R-HSA-2984213)
0.544
2
UniProt:O43683 BUB1
1
BUB1 [cytosol]
(R-HSA-377888)
0.544
2
UniProt:Q9H6L5-1 RETREG1
0.536
2
UniProt:Q9GZQ8 MAP1LC3B
3
MAP1LC3B [autophagosome membrane]
(R-HSA-5683641)
MAP1LC3B(2-121) [cytosol]
(R-HSA-5682674)
MAP1LC3B [cytosol]
(R-HSA-5205651)
0.527
4
UniProt:Q14145 KEAP1
3
Ub-KEAP1 [cytosol]
(R-HSA-6782766)
ub-KEAP1 [cytosol]
(R-HSA-9766647)
KEAP1 [cytosol]
(R-HSA-976038)
0.527
2
UniProt:Q676U5 ATG16L1
1
ATG16L1 [cytosol]
(R-HSA-5671734)
0.525
2
UniProt:Q14677 CLINT1
1
CLINT1 [cytosol]
(R-HSA-429811)
0.525
2
UniProt:P40939 HADHA
1
HADHA [mitochondrial inner membrane]
(R-HSA-77264)
0.525
4
UniProt:O75323 GBAS
1
NIPSNAP2 [cytosol]
(R-HSA-9714668)
0.525
4
UniProt:Q9H1Y0 ATG5
3
ATG5 [phagocytic vesicle membrane]
(R-HSA-5205636)
GlyK130-ATG5 [cytosol]
(R-HSA-5683582)
ATG5 [cytosol]
(R-HSA-936010)
0.525
2
UniProt:Q8WYN0 ATG4A
1
ATG4A [cytosol]
(R-HSA-5671857)
0.519
2
UniProt:Q14151 SAFB2
0.499
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.491
4
UniProt:P60520 GABARAPL2
3
GABARAPL2 [autophagosome membrane]
(R-HSA-5683633)
GABARAPL2(1-117) [cytosol]
(R-HSA-5682641)
GABARAPL2 [cytosol]
(R-HSA-5671758)
0.483
2
UniProt:Q9NX00 TM160
0.483
5
UniProt:Q9BSB4 ATG101
2
ATG101 [cytosol]
(R-HSA-5333634)
ATG101 [endoplasmic reticulum membrane]
(R-HSA-8948051)
0.483
2
UniProt:O43516 WIPF1
1
WIPF1 [cytosol]
(R-HSA-201874)
0.463
4
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