TICAM1 S186L

Stable Identifier
R-HSA-5607964
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
22105173 Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

Sancho-Shimizu, V, Pérez de Diego, R, Lorenzo, L, Halwani, R, Alangari, A, Israelsson, E, Fabrega, S, Cardon, A, Maluenda, J, Tatematsu, M, Mahvelati, F, Herman, M, Ciancanelli, M, Guo, Y, AlSum, Z, Alkhamis, N, Al-Makadma, AS, Ghadiri, A, Boucherit, S, Plancoulaine, S, Picard, C, Rozenberg, F, Tardieu, M, Lebon, P, Jouanguy, E, Rezaei, N, Seya, T, Matsumoto, M, Chaussabel, D, Puel, A, Zhang, SY, Abel, L, Al-Muhsen, S, Casanova, JL

J. Clin. Invest. 2011
External Reference Information
External Reference
UniProt:Q8IUC6 TICAM1
Gene Names
TICAM1, PRVTIRB, TRIF
Chain
chain:1-712
Reference Genes
BioGPS Gene:148022 TICAM1
COSMIC (genes):TICAM1 TICAM1
CTD Gene:148022 TICAM1
dbSNP Gene:148022 TICAM1
ENSEMBL:ENSG00000127666 TICAM1
ENSEMBL:ENSG00000127666 TICAM1
HGNC:18348 TICAM1
KEGG Gene (Homo sapiens):hsa:148022 TICAM1
Monarch:148022 TICAM1
NCBI Gene:148022 TICAM1
OMIM:607601 TICAM1
UCSC:Q8IUC6 TICAM1
Reference Transcript
Other Identifiers
0003870093
0007040520
11719258_at
148022
16867409
213191_at
2M1X
2M63
35230_at
3846983
3846984
3846985
3846986
3846987
3846988
3846989
3846990
3846991
3846992
3846993
3846994
3846995
3846996
3846997
3846998
3846999
3RC4
42460
4BSX
4C0M
5JEL
8032899
A_23_P376096
A_23_P90311
AAC28630
AAH09860
AAI36557
AAI36558
AAO85488
AB086380
AB093555
AB097023
AB446484
AF070530
AF492646
BAC44839
BAC55579
BAC77376
BAG55261
BC009860
BC136556
BC136557
CCDS12136
ENSG00000127666
ENSP00000248244
ENST00000248244
EntrezGene:148022
GE54626
GE803521
GO:0002281
GO:0002376
GO:0002756
GO:0003674
GO:0004871
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005768
GO:0005773
GO:0005776
GO:0005829
GO:0006464
GO:0006914
GO:0006915
GO:0006950
GO:0006954
GO:0007165
GO:0007249
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0010008
GO:0010508
GO:0010628
GO:0019899
GO:0019901
GO:0030890
GO:0031398
GO:0031410
GO:0031663
GO:0032092
GO:0032481
GO:0032496
GO:0032755
GO:0032760
GO:0032816
GO:0034128
GO:0034138
GO:0034641
GO:0035666
GO:0043123
GO:0043226
GO:0043330
GO:0043496
GO:0045080
GO:0045087
GO:0045359
GO:0045429
GO:0050871
GO:0051092
GO:0051607
GO:0070266
GO:0071222
GO:0097190
GO:0097342
GO:0140052
GO:1900017
HGNC:18348
HPA042460
Hs.29344.0.S1_3p_at
ILMN_1724863
ILMN_1815079
IPR017278
IPR025735
IPR035897
LRG_358
LRG_358t1
MIM:607601
MIM:614850
NM_182919
NP_891549
PF12721
PH_hs_0002548
TC19001071.hg
TICAM1
TICAM1-201
uc002mbi.5
UPI000000D72E
Participant Of
hasMember
Other forms of this molecule
TICAM1 R141* [cytosol]
TICAM1 [endosome membrane]
TICAM1 [cytosol]
Modified Residues
Name
L-serine 186 replaced with L-leucine
Coordinate
186
PsiMod HEY
L-leucine residue [MOD:00020]
A protein modification that effectively converts a source amino acid residue to an L-leucine.
L-serine removal [MOD:01646]
A protein modification that effectively removes or replaces an L-serine.
Disease
Name Identifier Synonyms
primary immunodeficiency disease 612 immune deficiency disorder, immunodeficiency syndrome, hypoimmunity
Cross References
RefSeq
GeneCards
DOCK Blaster
PRO
Orphanet
PDB
Interactors (1)