Reactome | RNF2 [nucleoplasm]

RNF2 [nucleoplasm]

Stable Identifier

R-HSA-389119

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RING2, E3 ubiquitin-protein ligase RING2, RING1B

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99496 RNF2

Gene Names

RNF2, BAP1, DING, HIPI3, RING1B

Chain

initiator methionine:, chain:2-336

Reference Genes

BioGPS Gene:6045 RNF2

COSMIC (genes):BAP1 RNF2

COSMIC (genes):RNF2 RNF2

CTD Gene:6045 RNF2

dbSNP Gene:6045 RNF2

ENSEMBL:ENSG00000121481 RNF2

HGNC:10061 RNF2

KEGG:hsa:6045 RNF2

Monarch:6045 RNF2

NCBI Gene:6045 RNF2

OMIM:608985 RNF2

UCSC:Q99496 RNF2

Reference Transcript

Other Identifiers

11728230_s_at

11728231_at

16674998

205215_PM_at

205215_at

2371705

2371706

2371707

2371718

2371719

2371720

2371721

2371722

2371723

2371724

2371726

2371727

2371728

3198021

3198024

3198025

33484_at

60269_i_at

60270_r_at

6045

7908169

A_14_P133195

A_23_P85543

A_24_P199500

GE62501

GO:0000122

GO:0000151

GO:0000278

GO:0000791

GO:0000792

GO:0001702

GO:0001739

GO:0003682

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006325

GO:0006338

GO:0006355

GO:0007281

GO:0008270

GO:0009948

GO:0010467

GO:0016567

GO:0016604

GO:0016740

GO:0022414

GO:0031519

GO:0035102

GO:0040029

GO:0043226

GO:0043433

GO:0046872

GO:0048856

GO:0061630

GO:0071339

GO:0071535

GO:0140096

GO:0140862

HMNXSV003001400

HMNXSV003017777

ILMN_1651715

PH_hs_0031611

TC01001595.hg

Y10571_at

g6005746_3p_at

Participates

as a component of

as a member of

RING1,RNF2 [nucleoplasm] (Homo sapiens)

Inferred To

RNF2 [nucleoplasm] (Bos taurus)

RNF2 [nucleoplasm] (Canis familiaris)

RNF2 [nucleoplasm] (Gallus gallus)

RNF2 [nucleoplasm] (Sus scrofa)

spat-3 [nucleoplasm] (Caenorhabditis elegans)

rnf2 [nucleoplasm] (Danio rerio)

rnf2 [nucleoplasm] (Xenopus tropicalis)

Sce [nucleoplasm] (Drosophila melanogaster)

Rnf2 [nucleoplasm] (Mus musculus)

Rnf2 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_009143.1, XP_011508153.1, XP_011508154.1

OpenTargets

ENSG00000121481

ENSEMBL

ENSP00000356479, ENSP00000356480, ENSG00000121481, ENST00000367509, ENST00000367510

HPA

ENSG00000121481-RNF2

GeneCards

RNF2

PRO

Q99496

Pharos - Targets

Q99496

GlyGen

Q99496

PDB

6WI7, 3GS2, 2H0D, 3H8H, 4R8P, 6WI8, 8GRM, 8PP7, 4S3O, 3RPG, 3IXS, 7ND1

HMDB Protein

HMDBP11563

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35227 PCGF2	1	PCGF2 [nucleoplasm] (R-HSA-389115)	0.945	18
UniProt:Q9BYE7 PCGF6	1	PCGF6 [nucleoplasm] (R-HSA-8953572)	0.845	8
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.802	6
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.788	7
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [secretory granule lumen] (R-HSA-6801319)	0.744	5
UniProt:O75461 E2F6	2	E2F6 [nucleoplasm] (R-HSA-8953089) p-S12-E2F6 [nucleoplasm] (R-HSA-9007536)	0.725	5
UniProt:Q93009 USP7	2	USP7 [nucleoplasm] (R-HSA-3215278) USP7 [cytosol] (R-HSA-8853511)	0.688	5
UniProt:P51668 UBE2D1	4	UBE2D1 [cytosol] (R-HSA-174236) UBE2D1 [nucleoplasm] (R-HSA-174197) Ub-C85-UBE2D1 [cytosol] (R-HSA-8864160) Ub-C85-UBE2D1 [nucleoplasm] (R-HSA-8937534)	0.666	4
UniProt:P61077 UBE2D3	3	Ub-C85-UBE2D3 [cytosol] (R-HSA-8864191) UBE2D3 [cytosol] (R-HSA-934630) UBE2D3 [nucleoplasm] (R-HSA-205341)	0.666	6
UniProt:P63208 SKP1	2	SKP1 [cytosol] (R-HSA-174150) SKP1 [nucleoplasm] (R-HSA-187538)	0.643	5
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.643	4
UniProt:Q969R5 L3MBTL2	2	L3MBTL2 [nucleoplasm] (R-HSA-6804477) polySUMO2-K675,K700-L3MBTL2 [nucleoplasm] (R-HSA-6804480)	0.643	6
UniProt:P08183 ABCB1	1	ABCB1 [plasma membrane] (R-HSA-1457534)	0.508	2
UniProt:Q9H7Z6 KAT8	1	KAT8 [nucleoplasm] (R-HSA-3321802)	0.499	2

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