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TBCB [cytosol]
Stable Identifier
R-HSA-379546
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tubulin-folding cofactor B
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Post-chaperonin tubulin folding pathway (Homo sapiens)
alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B (Homo sapiens)
Cofactor B:GTP-alpha tubulin [cytosol] (Homo sapiens)
TBCB [cytosol] (Homo sapiens)
TBCB [cytosol] (Homo sapiens)
alpha-tubulin:GTP:Cofactor B +Cofactor E -> alpha-tubulin:GTP: Cofactor E +Cofactor B (Homo sapiens)
Cofactor B:GTP-alpha tubulin [cytosol] (Homo sapiens)
TBCB [cytosol] (Homo sapiens)
TBCB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99426 TBCB
Gene Names
TBCB, CG22, CKAP1
Chain
chain:1-244
Reference Genes
BioGPS Gene:1155 TBCB
COSMIC (genes):TBCB TBCB
CTD Gene:1155 TBCB
dbSNP Gene:1155 TBCB
ENSEMBL:ENSG00000105254 TBCB
ENSEMBL_homo_sapiens_GENE:ENSG00000105254.12 TBCB
HGNC:1989 TBCB
KEGG Gene (Homo sapiens):1155 TBCB
Monarch:1155 TBCB
NCBI Gene:1155 TBCB
OMIM:601303 TBCB
UCSC:Q99426 TBCB
Reference Transcript
RefSeq:NM_001281.2 TBCB
RefSeq:NM_001300971.1 TBCB
Other Identifiers
1155
11715580_a_at
16861367
201804_PM_x_at
201804_x_at
211759_PM_x_at
211759_x_at
216194_PM_s_at
216194_s_at
34338_at
3831145
3831146
3831147
3831148
3831152
3831153
3831154
3831159
3831161
3831162
8028162
A_14_P133573
A_23_P56249
D49738_at
GE81001
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005938
GO:0006457
GO:0007010
GO:0007021
GO:0007023
GO:0007399
GO:0008092
GO:0015630
GO:0030154
GO:0031122
GO:0035371
GO:0043014
GO:0043226
GO:0048856
GO:0051010
GO:0065003
HMNXSV003015396
Hs.31053.1.S1_3p_s_at
ILMN_1790953
PH_hs_0002652
PH_hs_0031132
TC19000495.hg
Participates
as an output of
alpha-tubulin:GTP:Cofactor B +Cofactor E -> alpha-tubulin:GTP: Cofactor E +Cofactor B (Homo sapiens)
as a component of
Cofactor B:GTP-alpha tubulin [cytosol] (Homo sapiens)
as an input of
alpha-tubulin:GTP + Cofactor B -> alpha-tubulin:GTP: Cofactor B (Homo sapiens)
Cross References
RefSeq
NP_001272.2
,
NP_001287900.1
OpenTargets
ENSG00000105254
HPA
ENSG00000105254-TBCB
GeneCards
Q99426
Ensembl
ENST00000585746
,
ENSG00000105254
,
ENSP00000467487
,
ENST00000221855
,
ENSP00000221855
PRO
Q99426
Pharos - Targets
Q99426
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P68366 TUBA4A
9
TUBA4A [cytosol]
(R-HSA-191694)
TUBA4A [axonemal microtubule]
(R-HSA-5610443)
TUBA4A [extracellular region]
(R-HSA-350734)
Polyglutamyl-TUBA4A [cytosol]
(R-HSA-8867386)
L-isoglutamyl polyglycyl-TUBA4A [cytosol]
(R-HSA-8867378)
TUBA4A unfolded [cytosol]
(R-HSA-392771)
TUBA4A folding intermediate [cytosol]
(R-HSA-392800)
Ac K40 TUBA4A [axonemal microtubule]
(R-HSA-5624859)
AcK-TUBA4A [cytosol]
(R-HSA-5618318)
0.589
2
UniProt:Q9H2C0 GAN
1
GAN [cytosol]
(R-HSA-976014)
0.508
3
UniProt:Q93009 USP7
2
USP7 [cytosol]
(R-HSA-8853511)
USP7 [nucleoplasm]
(R-HSA-3215278)
0.508
2
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