DAXX binds Ub-MDM2 and USP7

Stable Identifier
R-HSA-3222072
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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DAXX paired amphipathic helix domain 2 (PAH2) binds MDM2, while DAXX PAH1 domain and acid rich region simultaneously bind USP7 (HAUSP) (Tang et al. 2006), forming a tripartite complex.

Literature References
PubMed ID Title Journal Year
16845383 Critical role for Daxx in regulating Mdm2

Tang, J, Qu, LK, Zhang, J, Wang, W, Michaelson, JS, Degenhardt, YY, El-Deiry, WS, Yang, X

Nat. Cell Biol. 2006
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