p-S423,S425-SMAD3 R268H

Stable Identifier
R-HSA-3315080
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-Ser423,Ser425-SMAD3 Arg268His
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
SMAD3, MADH3
Chain
initiator methionine:1, chain:2-425
Other Identifiers
0000380136
0005860086
11718265_a_at
11718266_s_at
11726549_a_at
11751185_a_at
11754091_s_at
1433_g_at
1454_at
1950_s_at
1MHD
1MJS
1MK2
1OZJ
1U7F
205396_at
205397_x_at
205398_s_at
218284_at
2LAJ
2LB2
3598961
3598977
3598984
3598992
3598993
3598994
3598995
3598997
3598999
3599014
3599016
3599023
3599028
3599029
3599030
3599031
3599032
3599033
3599034
3599035
3599036
3599037
38944_at
4088
44841_at
44986_s_at
46386
51059_at
58763_at
5OD6
5ODG
65983_at
67203
69409
7984364
8094
A0A024R5Z3
A_14_P107358
A_23_P48936
AAB18967
AAB80960
AAH50743
AAL68976
AB004930
AC012568
AC087482
AF025293
AF025294
AF025295
AF025296
AF025297
AF025298
AF025299
AF025300
AK290881
AK298139
AK300614
AK316017
BAA22032
BAF83570
BAH12731
BAH13315
BAH14388
BC050743
CAB008094
CAB069409
CCDS10222
CCDS45288
CCDS53950
CCDS53951
CH471082
EAW77788
EAW77789
EAW77790
ENSG00000166949
ENSP00000332973
ENSP00000401133
ENSP00000437757
ENSP00000445348
ENST00000327367
ENST00000439724
ENST00000537194
ENST00000540846
EntrezGene:4088
g1673576_3p_s_at
g5174512_3p_s_at
g7661691_3p_at
GE56446
GE79350
GO:0000122
GO:0000228
GO:0000278
GO:0000790
GO:0000977
GO:0000978
GO:0000981
GO:0000983
GO:0000987
GO:0000988
GO:0000989
GO:0001102
GO:0001228
GO:0001501
GO:0001649
GO:0001657
GO:0001666
GO:0001701
GO:0001707
GO:0001756
GO:0001889
GO:0001947
GO:0002076
GO:0002376
GO:0002520
GO:0003013
GO:0003674
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0003723
GO:0004871
GO:0005160
GO:0005515
GO:0005518
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005637
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006412
GO:0006464
GO:0006605
GO:0006810
GO:0006913
GO:0006919
GO:0006950
GO:0006955
GO:0007010
GO:0007049
GO:0007050
GO:0007155
GO:0007165
GO:0007179
GO:0007183
GO:0007267
GO:0007369
GO:0007492
GO:0008013
GO:0008134
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0008285
GO:0009056
GO:0009058
GO:0009790
GO:0009880
GO:0010628
GO:0010694
GO:0010718
GO:0016202
GO:0016579
GO:0017015
GO:0017151
GO:0019049
GO:0019899
GO:0019901
GO:0019902
GO:0022607
GO:0023019
GO:0030154
GO:0030198
GO:0030308
GO:0030325
GO:0030335
GO:0030501
GO:0030512
GO:0030618
GO:0030878
GO:0031053
GO:0031490
GO:0031625
GO:0031962
GO:0032182
GO:0032332
GO:0032731
GO:0032909
GO:0032916
GO:0032924
GO:0032991
GO:0033689
GO:0034330
GO:0034641
GO:0035259
GO:0035326
GO:0038092
GO:0040007
GO:0040011
GO:0042060
GO:0042110
GO:0042177
GO:0042307
GO:0042592
GO:0042802
GO:0042803
GO:0043066
GO:0043130
GO:0043167
GO:0043226
GO:0043235
GO:0043425
GO:0043565
GO:0044212
GO:0044403
GO:0045216
GO:0045429
GO:0045599
GO:0045668
GO:0045893
GO:0045930
GO:0045944
GO:0046332
GO:0046872
GO:0046982
GO:0048340
GO:0048589
GO:0048617
GO:0048646
GO:0048701
GO:0048856
GO:0048870
GO:0050678
GO:0050728
GO:0050776
GO:0050821
GO:0050927
GO:0051091
GO:0051098
GO:0051481
GO:0051496
GO:0051894
GO:0060039
GO:0060070
GO:0060290
GO:0060395
GO:0061045
GO:0061767
GO:0065003
GO:0070306
GO:0070410
GO:0070412
GO:0070878
GO:0071141
GO:0071144
GO:0071345
GO:0071560
GO:0090263
GO:0097191
GO:0097296
GO:1901203
GO:1902895
GO:1903243
H0YKE2
H0YL71
H0YMP2
H0YMY0
H0YNV1
H3BP09
H3BVD1
HGNC:6769
HPA046386
HPA067203
Hs.211578.0.S3_3p_at
ILMN_1682738
IPR001132
IPR003619
IPR008984
IPR013019
IPR013790
IPR017855
IPR036578
MIM:603109
MIM:613795
NM_001145102
NM_001145103
NM_001145104
NM_005902
NP_001138574
NP_001138575
NP_001138576
NP_005893
PF03165
PF03166
PH_hs_0032513
PH_hs_0039929
SM00523
SM00524
SMAD3
SMAD3-201
SMAD3-202
SMAD3-203
SMAD3-204
TC15000622.hg
TC15002251.hg
U68019
U68019_at
U76622
uc002aqj.4
uc010ujr.3
uc010ujs.3
uc010ujt.3
UPI0000023A91
UPI000047B413
UPI0001915047
UPI000192B90A
XM_011521559
XM_011521560
XP_011519861
XP_011519862
Participant Of
Other forms of this molecule
Modified Residues
Name
L-arginine residue 268 replaced with L-histidine
Coordinate
268
PsiMod HEY
A protein modification that effectively converts a source amino acid residue to an L-histidine.
A protein modification that effectively converts a source amino acid residue to an L-arginine.
Name
O-phospho-L-serine at 423
Coordinate
423
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 425
Coordinate
425
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
lung cancer 1324
malignant neoplasm of large intestine 5672 malignant Colorectal tumor, malignant neoplasm of large intestine, NOS, malignant tumor of large intestine (disorder), malignant neoplasm of colon with rectum, malignant neoplasm of large intestine NOS
Cross References
COSMIC
GeneCards
PRO
Orphanet
Interactors (54)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q13485 SMAD4  18 0.97 24
 UniProt:P12755 SKI  1 0.842 11
 UniProt:Q9H2G9 BLZF1  1 0.795 8
 UniProt:Q9H0M0 WWP1  1 0.795 8
 UniProt:Q9HAU4 SMURF2  2 0.787 7
 UniProt:O00308 WWP2  1 0.779 7
 UniProt:P50222 MEOX2      0.718 6
 IntAct:EBI-11522976 CCDC33      0.696 5
 UniProt:Q13573 SNW1  1 0.69 5
 UniProt:O43524 FOXO3  7 0.667 5
 UniProt:P84022 SMAD3  15 0.656 3
 UniProt:O75593 FOXH1  1 0.635 5
 UniProt:O95405 ZFYVE9      0.592 2
 UniProt:Q64729  3 0.576 6
 UniProt:Q9BZ29 DOCK9  1 0.576 3
 UniProt:Q15796 SMAD2  21 0.573 2
 UniProt:Q99814 EPAS1  5 0.573 2
 UniProt:Q93009 USP7  2 0.573 2
 UniProt:P10070 GLI2  11 0.558 4
 UniProt:Q8N684-3 CPSF7      0.556 3
 UniProt:Q08117 AES  1 0.556 3
 UniProt:Q8IXK0-5 PHC2      0.556 3
 UniProt:Q08117-2 AES      0.556 3
 UniProt:O43186 CRX      0.556 3
 UniProt:Q8WW24 TEKT4      0.556 3
 UniProt:Q8N684 CPSF7  1 0.556 3
 UniProt:Q8IXK0 PHC2  1 0.556 3
 IntAct:EBI-10171584 80125      0.556 3
 UniProt:P15822 ZEP1      0.553 2
 UniProt:Q13501 SQSTM1  2 0.543 3
 UniProt:Q99836 MYD88  9 0.543 3
 UniProt:P51141 Dvl1  4 0.527 2
 UniProt:P98082 DAB2  3 0.524 3
 UniProt:Q9NYA4 MTMR4  2 0.524 2
 UniProt:Q9H2X0 CHRD      0.508 2
 UniProt:Q9BZL4 PP12C      0.508 2
 UniProt:Q96EP0 RNF31  1 0.508 2
 UniProt:Q9Y3Q8 T22D4      0.508 2
 UniProt:Q5D1E8 ZC12A      0.508 2
 UniProt:Q9BYW2 SETD2  1 0.508 2
 UniProt:Q16822 PCK2  1 0.508 2
 UniProt:Q05066 SRY  1 0.499 3
 UniProt:P17844 DDX5  3 0.499 2
 UniProt:P46934-3 NEDD4      0.488 2
 UniProt:Q9UBR4-2 LHX3      0.488 2
 UniProt:Q86YD7 F90A1      0.488 2
 UniProt:P20618 PSMB1  5 0.488 2
 UniProt:P0C264 SBK3      0.488 2
 UniProt:E9PSE9 E9PSE9      0.488 2
 UniProt:P23142 FBLN1  1 0.488 2
 UniProt:Q93062-3 RBPMS      0.488 2
 UniProt:Q6NX45 ZNF774  1 0.488 2
 UniProt:Q9NZH6 IL37  6 0.463 2
 UniProt:Q16665 HIF1A  6 0.463 6