Reactome | USP11 [cytosol]

USP11 [cytosol]

Stable Identifier

R-HSA-391303

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P51784 USP11

Gene Names

USP11, UHX1

Chain

chain:1-963

Reference Genes

COSMIC (genes):USP11 USP11

ENSEMBL:ENSG00000102226 USP11

ENSEMBL_homo_sapiens_GENE:ENSG00000102226.10 USP11

HGNC:12609 USP11

OMIM:300050 USP11

UCSC:P51784 USP11

Reference Transcript

Other Identifiers

11727035_at

162_at

17103104

208723_PM_at

208723_at

3976165

3976166

3976167

3976168

3976169

3976170

3976176

3976177

3976178

3976179

3976181

3976183

3976184

3976185

3976186

3976188

3976189

3976191

3976192

3976193

3976195

3976196

3976197

3976202

3976204

3976205

3976206

3976207

3976208

3976210

3976212

3976215

3976216

3976217

3976218

3976219

8167125

8237

A_23_P171366

A_33_P3273173

GE81425

GO:0001222

GO:0003824

GO:0004197

GO:0004843

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006508

GO:0008233

GO:0008234

GO:0016579

GO:0016787

GO:0036211

GO:0043226

GO:0140096

HMNXSV003018628

ILMN_1664537

PH_hs_0010270

TC0X000231.hg

U44839_at

g12653164_3p_at

Participates

as a candidate of

unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)

as a component of

Inferred To

Usp11 [cytosol] (Mus musculus)

Usp11 [cytosol] (Rattus norvegicus)

CDK16 [cytosol] (Canis familiaris)

USP11 [cytosol] (Bos taurus)

USP11 [cytosol] (Sus scrofa)

Cross References

RefSeq

XP_011542290.1, NP_004642.2, XP_005272731.1

OpenTargets

ENSG00000102226

GeneCards

P51784

HPA

ENSG00000102226-USP11

Ensembl

ENSP00000218348, ENST00000218348, ENSG00000102226

PRO

P51784

Pharos - Targets

P51784

HMDB Protein

HMDBP11553

PDB

8OYP, 5OK6, 4MEL

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q93009 USP7	2	USP7 [cytosol] (R-HSA-8853511) USP7 [nucleoplasm] (R-HSA-3215278)	0.643	3
UniProt:Q9H0Y0 ATG10	2	GlyK166-ATG10 [cytosol] (R-HSA-5683572) ATG10 [cytosol] (R-HSA-5671733)	0.615	3
UniProt:P35227 PCGF2	1	PCGF2 [nucleoplasm] (R-HSA-389115)	0.591	5
UniProt:P04608 tat	1	Tat (P04608) [nucleoplasm] (R-HIV-175856)	0.558	3
UniProt:Q9NUI1 DECR2	2	DECR2 [cytosol] (R-HSA-9033149) DECR2 [peroxisomal membrane] (R-HSA-6786710)	0.556	3
UniProt:Q13107 USP4	1	USP4 [cytosol] (R-HSA-5212663)	0.527	2
UniProt:Q16539 MAPK14	7	MAPK14 [secretory granule lumen] (R-HSA-6803300) MAPK14 [extracellular region] (R-HSA-6806453) MAPK14 [ficolin-1-rich granule lumen] (R-HSA-6803280) MAPK14 [nucleoplasm] (R-HSA-446223) MAPK14 [cytosol] (R-HSA-428933) p-T180,Y182-MAPK14 [cytosol] (R-HSA-428935) p-T180,Y182-MAPK14 [nucleoplasm] (R-HSA-446227)	0.527	2
UniProt:Q86YC2 PALB2	20	PALB2 Y28C [nucleoplasm] (R-HSA-9724169) PALB2 L35P [nucleoplasm] (R-HSA-9724168) PALB2 L24S [nucleoplasm] (R-HSA-9724172) PALB2 L21A [nucleoplasm] (R-HSA-9704339) PALB2 R37H [nucleoplasm] (R-HSA-9724178) PALB2 L21F [nucleoplasm] (R-HSA-9704347) PALB2 E12* [nucleoplasm] (R-HSA-9704349) PALB2 R37C [nucleoplasm] (R-HSA-9724188) PALB2 L35F [nucleoplasm] (R-HSA-9704338) PALB2 L947F [nucleoplasm] (R-HSA-9724554) PALB2 G1043D [nucleoplasm] (R-HSA-9724584) PALB2 T1030I [nucleoplasm] (R-HSA-9704424) PALB2 T841Qfs10 [nucleoplasm] (R-HSA-9704749) PALB2 L1119P [nucleoplasm] (R-HSA-9724589) PALB2 L947S [nucleoplasm] (R-HSA-9724557) PALB2 L1143P [nucleoplasm] (R-HSA-9704428) PALB2 L1070P [nucleoplasm] (R-HSA-9724556) PALB2 C77Vfs100 [nucleoplasm] (R-HSA-9704738) PALB2 L939W [nucleoplasm] (R-HSA-9704417) PALB2 L961P [nucleoplasm] (R-HSA-9724583)	0.499	2

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