p-Y542-PTPN11 [cytosol]

Stable Identifier
R-HSA-1369081
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p(Y)-SHP2, Tyrosine-protein phosphatase non-receptor type 11, PTN11_HUMAN, PTPN11
p-Y542-PTPN11 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PTPN11, PTP2C, SHPTP2
Chain
initiator methionine:, chain:2-593
Other Identifiers
11729206_at
11729207_s_at
11729208_x_at
11761200_at
1552637_PM_at
1552637_at
16757255
1870_at
1871_g_at
205867_PM_at
205867_at
205868_PM_s_at
205868_s_at
209895_PM_at
209895_at
209896_PM_s_at
209896_s_at
212610_PM_at
212610_at
2687514
2775657
2851175
3136729
3136745
3432334
3432340
3432342
3432343
3432344
3432345
3432350
3432351
3432352
3432353
3432354
3432357
3432358
3432359
3432360
3432365
3432367
3432368
3432369
3432370
3432371
3432372
3432373
3432374
3432375
3432376
38443_at
5781
7958846
A_14_P201950
A_23_P204090
A_23_P99027
A_32_P61757
D13540_at
GE59447
GE79583
GO:0000077
GO:0000278
GO:0001784
GO:0002376
GO:0003824
GO:0004721
GO:0004725
GO:0004726
GO:0005158
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006470
GO:0006629
GO:0006641
GO:0006886
GO:0006913
GO:0007155
GO:0007165
GO:0007173
GO:0007229
GO:0007409
GO:0007420
GO:0007507
GO:0008543
GO:0009755
GO:0009967
GO:0016311
GO:0016787
GO:0016791
GO:0019221
GO:0019901
GO:0021697
GO:0022414
GO:0023052
GO:0030154
GO:0030159
GO:0030220
GO:0030971
GO:0031295
GO:0032331
GO:0032480
GO:0032528
GO:0032728
GO:0032755
GO:0032760
GO:0032991
GO:0033628
GO:0033629
GO:0035264
GO:0035265
GO:0035335
GO:0035855
GO:0036211
GO:0036302
GO:0038127
GO:0042445
GO:0042593
GO:0043226
GO:0043254
GO:0043408
GO:0045296
GO:0045778
GO:0045931
GO:0046326
GO:0046628
GO:0046676
GO:0046825
GO:0046887
GO:0046888
GO:0048008
GO:0048011
GO:0048013
GO:0048609
GO:0048806
GO:0048839
GO:0048856
GO:0048870
GO:0048873
GO:0050731
GO:0050839
GO:0050886
GO:0051428
GO:0051463
GO:0055085
GO:0060020
GO:0060090
GO:0060125
GO:0060325
GO:0060338
GO:0061582
GO:0065003
GO:0070374
GO:0071310
GO:0071364
GO:0098542
GO:0140096
GO:1990782
HMNXSV003024186
Hs.83572.0.S1_3p_at
Hs2.22868.1.S1_3p_at
ILMN_1778236
PH_hs_0027176
TC12000881.hg
TC12002571.hg
U79291_at
g13430845_3p_at
g292406_3p_a_at
g7770146_RC_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
O4'-phospho-L-tyrosine at 542
Coordinate
542
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Metabolites
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (40)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q13480 GAB1  4 0.957 42
 UniProt:P62993 GRB2  1 0.905 11
 UniProt:P09619 PDGFRB  3 0.902 8
 UniProt:P00533 EGFR  20 0.821 8
 UniProt:P08069 IGF1R  3 0.772 5
 UniProt:P80200 CGA1      0.77 8
 UniProt:Q13049 TRIM32  1 0.742 5
 UniProt:P16284 PECAM1  5 0.69 7
 UniProt:P20138 CD33  3 0.677 5
 UniProt:O95297 MPZL1      0.669 5
 UniProt:P49247 RPIA  2 0.666 4
 UniProt:P29317 EPHA2  2 0.665 3
 UniProt:P35570 Irs1  7 0.656 3
 UniProt:P06213 INSR  6 0.65 3
 UniProt:Q8WU20 FRS2  6 0.649 4
 UniProt:Q9UQC2 GAB2  5 0.643 4
 UniProt:P32239 CCKBR  1 0.623 5
 UniProt:P08581 MET  7 0.609 13
 UniProt:P49023 PXN  4 0.604 3
 UniProt:Q15116 PDCD1  2 0.602 3
 UniProt:P04626 ERBB2  20 0.592 3
 UniProt:Q08345 DDR1  1 0.576 4
 UniProt:Q15303 ERBB4      0.573 2
 UniProt:P97710 Sirpa  6 0.564 3
 UniProt:P04040 CAT  5 0.544 3
 UniProt:P68105 EEF1A1  1 0.544 2
 UniProt:P19320 VCAM1  1 0.527 4
 UniProt:P48357 LEPR      0.527 2
 UniProt:P78324 SIRPA  4 0.527 3
 UniProt:Q8N1K5 THMS1      0.527 3
 UniProt:P32927 CSF2RB  6 0.527 2
 UniProt:Q9BZW8 CD244  1 0.525 5
 UniProt:P22455 FGFR4  12 0.519 2
 UniProt:P21802 FGFR2  20 0.519 2
 UniProt:Q03135 CAV1  5 0.499 2
 UniProt:P43626 KIR2DL1  1 0.488 2
 UniProt:P43628 KIR2DL3  1 0.462 4
 UniProt:Q13291 SLAF1      0.462 2
 UniProt:P36888 FLT3  20 0.462 2
 UniProt:Q9Y3P8 SIT1      0.462 2
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