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KIR2DL3 [plasma membrane]
Stable Identifier
R-HSA-3006532
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Killer cell immunoglobulin-like receptor 2DL3, KI2L3_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
KIR2DL2/3 interacting with HLA-C group 1 (Cw4) (Homo sapiens)
HLA-C group 1 interacting with KIR2DL2/3 [plasma membrane] (Homo sapiens)
HLA-C group-I-interacting KIRs [plasma membrane] (Homo sapiens)
KIR2DL3 [plasma membrane] (Homo sapiens)
HLA-C group-I-interacting KIRs [plasma membrane] (Homo sapiens)
KIR2DL3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P43628 KIR2DL3
Gene Names
KIR2DL3, CD158B2, KIRCL23, NKAT2
Chain
signal peptide:1-21, chain:22-341
Reference Genes
BioGPS Gene:3804 KIR2DL3
COSMIC (genes):KIR2DL3 KIR2DL3
CTD Gene:3804 KIR2DL3
dbSNP Gene:3804 KIR2DL3
ENSEMBL:ENSG00000243772 KIR2DL3
ENSEMBL:ENSG00000273887 KIR2DL3
ENSEMBL:ENSG00000274108 KIR2DL3
ENSEMBL:ENSG00000274402 KIR2DL3
ENSEMBL:ENSG00000274410 KIR2DL3
ENSEMBL:ENSG00000274830 KIR2DL3
ENSEMBL:ENSG00000274952 KIR2DL3
ENSEMBL:ENSG00000275008 KIR2DL3
ENSEMBL:ENSG00000275623 KIR2DL3
ENSEMBL:ENSG00000275658 KIR2DL3
ENSEMBL:ENSG00000276218 KIR2DL3
ENSEMBL:ENSG00000276459 KIR2DL3
ENSEMBL:ENSG00000276590 KIR2DL3
ENSEMBL:ENSG00000277317 KIR2DL3
ENSEMBL:ENSG00000277484 KIR2DL3
ENSEMBL:ENSG00000277554 KIR2DL3
ENSEMBL:ENSG00000277924 KIR2DL3
ENSEMBL:ENSG00000278327 KIR2DL3
ENSEMBL:ENSG00000283702 KIR2DL3
ENSEMBL:ENSG00000283708 KIR2DL3
ENSEMBL:ENSG00000283790 KIR2DL3
ENSEMBL:ENSG00000284333 KIR2DL3
ENSEMBL:ENSG00000284504 KIR2DL3
ENSEMBL:ENSG00000284510 KIR2DL3
HGNC:6331 KIR2DL3
KEGG Gene (Homo sapiens):3804 KIR2DL3
Monarch:3804 KIR2DL3
NCBI Gene:3804 KIR2DL3
OMIM:604938 KIR2DL3
UCSC:P43628 KIR2DL3
Reference Transcript
RefSeq:NM_015868.2 KIR2DL3
Other Identifiers
0002370504
11742301_x_at
16865470
16876286
1B6U
208179_x_at
31780_f_at
36886_f_at
36887_f_at
3804
3841708
3841715
3841717
3841719
3841720
3841721
3841723
3841724
3841725
3841726
3841728
3841729
3841730
3841731
3841732
3841734
3841735
3841737
3841740
3841742
3841743
3841746
3841747
3841749
3841750
3841751
3841753
3841755
3841757
3841760
3841763
3841766
3841768
3841769
3841774
3841775
3841776
3841778
3841782
3841785
3841809
3841811
3841814
3841819
3841824
3841829
3841834
3841836
3841837
3841841
3841843
3841845
3841846
3841849
3841851
3841854
3841858
4052951
4052957
4052958
4052961
4052963
4052965
4052968
4052969
4052970
4052971
4052975
4052976
4052977
4052978
4052992
4052996
4052997
4052998
4053003
4053005
4053009
4053021
4053022
4053023
4053026
4053027
4053045
4053046
4053047
4053048
4053049
4053050
4053052
4053058
4053061
4053062
4053063
4053064
4053065
4053066
4053067
4053069
4053075
8031277
8031293
8031297
8039829
8039842
8039896
A0A0C4ZLV8
A0A0G2JNW9
A0A0G2JPP8
AAA69869
AAB36590
AAB36591
AAB95321
AAC50333
AAC51147
AAC51651
AAD24477
AAH32422
AAH50730
ADN34702
AF022048
AGG79413
AGG79418
AGG79419
AH006692
AH007572
AJI80989
AJI80994
AJI81025
AJI81035
ANJ04789
ANJ04801
BC032422
BC050730
CCDS33107
E3NZD8
ENSG00000243772
ENSG00000273887
ENSG00000274108
ENSG00000274402
ENSG00000274410
ENSG00000274830
ENSG00000274952
ENSG00000275008
ENSG00000275623
ENSG00000275658
ENSG00000276218
ENSG00000276459
ENSG00000276590
ENSG00000277317
ENSG00000277484
ENSG00000277554
ENSG00000277924
ENSG00000278327
ENSG00000283702
ENSG00000283708
ENSG00000283790
ENSG00000284333
ENSG00000284504
ENSG00000284510
ENSP00000342215
ENSP00000478136
ENSP00000478657
ENSP00000478848
ENSP00000479121
ENSP00000480087
ENSP00000480464
ENSP00000481159
ENSP00000481237
ENSP00000481355
ENSP00000481478
ENSP00000482830
ENSP00000483192
ENSP00000483419
ENSP00000483551
ENSP00000483883
ENSP00000483975
ENSP00000484459
ENSP00000491264
ENSP00000491273
ENSP00000491452
ENSP00000491955
ENSP00000492356
ENSP00000492856
ENST00000342376
ENST00000342376.3
ENST00000610407
ENST00000611207
ENST00000611369
ENST00000611821
ENST00000611990
ENST00000614792
ENST00000615091
ENST00000615739
ENST00000617150
ENST00000617242
ENST00000617404
ENST00000617593
ENST00000617790
ENST00000619702
ENST00000619995
ENST00000620549
ENST00000622644
ENST00000638813
ENST00000638851
ENST00000639089
ENST00000639101
ENST00000639176
ENST00000640485
EntrezGene:3804
EntrezGene:KIR2DL3
FJ188693
g2760896_3p_x_at
GE510478
GO:0002376
GO:0003674
GO:0003823
GO:0005515
GO:0005575
GO:0005623
GO:0005886
GO:0005887
GO:0006955
GO:0008150
GO:0016020
GO:0016021
GO:0038023
GO:0050776
HGNC:6331
ILMN_1667232
IPR003599
IPR013151
IPR013783
IPR036179
KC261287
KC261292
KC261293
KIR2DL3
KIR2DL3-201
KIR2DL3-202
KIR2DL3-204
KIR2DL3-205
KIR2DL3-206
KIR2DL3-207
KIR2DL3-208
KIR2DL3-209
KIR2DL3-210
KIR2DL3-211
KIR2DL3-213
KIR2DL3-214
KIR2DL3-215
KIR2DL3-216
KIR2DL3-217
KIR2DL3-218
KIR2DL3-219
KIR2DL3-220
KIR2DL3-222
KIR2DL3-223
KIR2DL3-224
KIR2DL3-230
KIR2DL3-231
KIR2DL3-232
KP420438
KP420439
KP420443
KP420445
KU645196
KU645197
L41268
L41268_f_at
L76662
L76663
MIM:604938
NM_015868
NP_056952
PF00047
PH_hs_0029293
PH_hs_0030678
PH_hs_0034336
PH_hs_0039926
SM00409
TC19002236.hg
TC19002661.hg
U24074
U73395
UPI0000071361
UPI000012DB1C
X97230_f_at
Participant Of
hasMember
HLA-C group-I-interacting KIRs [plasma membrane]
Cross References
RefSeq
NP_056952.2
OpenTargets
ENSG00000243772
GeneCards
P43628
HPA
ENSG00000243772-KIR2DL3
Ensembl
ENSG00000275008
,
ENSG00000276459
,
ENST00000611990
,
ENST00000620549
,
ENSG00000274830
,
ENSG00000276590
,
ENST00000638851
,
ENSP00000481159
,
ENSG00000274108
,
ENSP00000342215
,
ENSP00000492856
,
ENST00000639101
,
ENSG00000284504
,
ENSP00000491264
,
ENST00000611821
,
ENST00000617404
,
ENST00000615739
,
ENST00000614792
,
ENSP00000481355
,
ENSP00000483883
,
ENSP00000492356
,
ENSP00000482830
,
ENSG00000278327
,
ENSG00000273887
,
ENSP00000478848
,
ENSG00000283702
,
ENSG00000283790
,
ENST00000640485
,
ENSP00000478657
,
ENST00000639089
,
ENSG00000274402
,
ENSP00000483192
,
ENSG00000275658
,
ENST00000342376
,
ENSP00000483551
,
ENST00000619995
,
ENSG00000276218
,
ENST00000622644
,
ENSP00000479121
,
ENST00000617242
,
ENSG00000274952
,
ENSP00000491273
,
ENST00000617790
,
ENST00000615091
,
ENST00000617593
,
ENSG00000283708
,
ENSG00000284333
,
ENST00000638813
,
ENSP00000481478
,
ENSP00000481237
,
ENST00000617150
,
ENSP00000483419
,
ENSG00000277484
,
ENST00000619702
,
ENSG00000274410
,
ENSG00000275623
,
ENSG00000277924
,
ENSP00000491955
,
ENSP00000483975
,
ENSP00000480464
,
ENSG00000284510
,
ENSP00000484459
,
ENST00000610407
,
ENSP00000491452
,
ENSG00000277554
,
ENSG00000277317
,
ENSG00000243772
,
ENSP00000480087
,
ENST00000611207
,
ENST00000611369
,
ENST00000639176
,
ENSP00000478136
PRO
P43628
PDB
1B6U
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29350 PTPN6
5
PTPN6 [extracellular region]
(R-HSA-6806315)
PTPN6 [tertiary granule lumen]
(R-HSA-6800952)
PTPN6 [specific granule lumen]
(R-HSA-6799641)
PTPN6 [nucleoplasm]
(R-HSA-9008911)
PTPN6 [cytosol]
(R-HSA-197938)
0.824
13
UniProt:P07204 THBD
1
THBD [plasma membrane]
(R-HSA-141030)
0.556
3
UniProt:P05090 APOD
1
APOD [extracellular region]
(R-HSA-5216199)
0.556
3
UniProt:P01350 GAST
1
GAST(76-92) [extracellular region]
(R-HSA-870266)
0.556
3
UniProt:Q8N8N0 RNF152
1
RNF152 [lysosomal membrane]
(R-HSA-8938832)
0.556
3
UniProt:Q8N661 TMEM86B
1
TMEM86B [endoplasmic reticulum membrane]
(R-HSA-8874443)
0.556
3
UniProt:O75396 SEC22B
6
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.556
3
UniProt:P02652 APOA2
6
APOA2(24-100) [early endosome]
(R-HSA-2569092)
APOA2(24-100) [endoplasmic reticulum lumen]
(R-HSA-174689)
APOA2(24-100) [cytosol]
(R-HSA-2395772)
APOA2(24-100) [extracellular region]
(R-HSA-174775)
p-APOA2 [endoplasmic reticulum lumen]
(R-HSA-8957014)
APOA2 [endoplasmic reticulum lumen]
(R-HSA-8956780)
0.556
3
UniProt:O43561-2 LAT
2
LAT-2 [plasma membrane]
(R-HSA-2396548)
p-5Y-LAT-2 [plasma membrane]
(R-HSA-2396597)
0.556
3
UniProt:Q8WVV5 BTN2A2
1
BTN2A2 [plasma membrane]
(R-HSA-8851047)
0.556
3
UniProt:Q01628 IFITM3
1
IFITM3 [plasma membrane]
(R-HSA-1015688)
0.556
3
UniProt:Q06124 PTPN11
4
PTPN11 [nucleoplasm]
(R-HSA-8937745)
p-Y546-PTPN11 [cytosol]
(R-HSA-1369081)
PTPN11 [cytosol]
(R-HSA-162563)
p-Y546,Y584-PTPN11 [cytosol]
(R-HSA-162573)
0.462
4
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