p5Y-FGFR4 Y367C mutant [plasma membrane]

Stable Identifier
R-HSA-2011873
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Icon
p5Y-FGFR4 Y367C mutant [plasma membrane] icon
p5Y-FGFR4 Y367C mutant [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P22455 FGFR4
Gene Names
FGFR4, JTK2, TKF
Chain
signal peptide:1-21, chain:22-802
Reference Genes
BioGPS Gene:2264 FGFR4
COSMIC (genes):FGFR4 FGFR4
CTD Gene:2264 FGFR4
dbSNP Gene:2264 FGFR4
ENSEMBL:ENSG00000160867 FGFR4
HGNC:3691 FGFR4
KEGG Gene (Homo sapiens):2264 FGFR4
Monarch:2264 FGFR4
NCBI Gene:2264 FGFR4
OMIM:134935 FGFR4
UCSC:P22455 FGFR4
Reference Transcript
Other Identifiers
0000110440
0001090372
0005290176
11735873_a_at
11740240_a_at
11744657_x_at
11752172_a_at
11753528_a_at
11757181_x_at
1291_s_at
1554962_a_at
16992957
204579_at
211237_s_at
2264
2842912
2842913
2842914
2842915
2842916
2842918
2842920
2842922
2842923
2842924
2842926
2842928
2842930
2842931
2842932
2842933
2842934
2842935
2842936
2842938
2842939
2842941
2842943
2842944
8110265
A_14_P131381
A_23_P92754
GE57553
GO:0000165
GO:0000166
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005794
GO:0005886
GO:0005887
GO:0005911
GO:0006259
GO:0006464
GO:0006468
GO:0006629
GO:0007165
GO:0007169
GO:0007275
GO:0008150
GO:0008201
GO:0008283
GO:0008284
GO:0008543
GO:0009058
GO:0010628
GO:0010715
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0017134
GO:0018108
GO:0019216
GO:0030133
GO:0030198
GO:0031410
GO:0032991
GO:0033674
GO:0034641
GO:0040011
GO:0042592
GO:0042593
GO:0042632
GO:0043085
GO:0043167
GO:0043226
GO:0043235
GO:0044281
GO:0045862
GO:0046777
GO:0048856
GO:0048870
GO:0051897
GO:0055062
GO:0070374
GO:0070857
GO:2000573
HMNXSV003054104
ILMN_1730355
ILMN_2241412
ILMN_2410713
L03840_s_at
PH_hs_0010000
TC05001010.hg
g13112051_3p_at
g6739817_3p_a_at
Participates
as a component of
Other forms of this molecule
FGFR4 Y367C [plasma membrane]
FGFR4 N535K [plasma membrane]
FGFR4 V550E [plasma membrane]
FGFR4 V550L [plasma membrane]
FGFR4 N535D [plasma membrane]
p-5Y-FGFR4 V550E [plasma membrane]
p-5Y-FGFR4 N535K [plasma membrane]
p-5Y-FGFR4 V550L [plasma membrane]
p-5Y-FGFR4 N535D [plasma membrane]
FGFR4 [plasma membrane]
p-5Y-FGFR4 [plasma membrane]
Modified Residues
Name
L-tyrosine 367 replaced with L-cysteine
Coordinate
367
PsiMod
L-tyrosine removal [MOD:01649]
A protein modification that effectively removes or replaces an L-tyrosine.
L-cysteine residue [MOD:00014]
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
Name
O4'-phospho-L-tyrosine at 642
Coordinate
642
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 643
Coordinate
643
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 719
Coordinate
719
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 754
Coordinate
754
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 764
Coordinate
764
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
breast cancer DOID:1612 malignant tumor of the breast, mammary cancer, malignant neoplasm of breast, mammary tumor, primary breast cancer, breast cancer, Ca breast - NOS, breast tumor
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
GlyGen
PDB
ZINC - Investigational
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
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