p5Y-FGFR4 Y367C mutant [plasma membrane]

Stable Identifier
R-HSA-2011873
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Icon
p5Y-FGFR4 Y367C mutant [plasma membrane] icon
p5Y-FGFR4 Y367C mutant [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P22455 FGFR4
Gene Names
FGFR4, JTK2, TKF
Chain
signal peptide:1-21, chain:22-802
Reference Genes
BioGPS Gene:2264 FGFR4
COSMIC (genes):FGFR4 FGFR4
CTD Gene:2264 FGFR4
dbSNP Gene:2264 FGFR4
ENSEMBL:ENSG00000160867 FGFR4
ENSEMBL_homo_sapiens_GENE:ENSG00000160867 FGFR4
HGNC:3691 FGFR4
KEGG Gene (Homo sapiens):2264 FGFR4
Monarch:2264 FGFR4
NCBI Gene:2264 FGFR4
OMIM:134935 FGFR4
UCSC:P22455 FGFR4
Reference Transcript
Other Identifiers
0000110440
0001090372
0005290176
11735873_a_at
11740240_a_at
11744657_x_at
11752172_a_at
11753528_a_at
11757181_x_at
1291_s_at
1554962_a_at
16992957
1QCT
204579_at
211237_s_at
2264
27273
27369
28251
2842913
2842914
2842915
2842916
2842918
2842920
2842922
2842923
2842924
2842926
2842928
2842930
2842931
2842932
2842933
2842934
2842935
2842936
2842938
2842939
2842941
2842943
2842944
4QQ5
4QQC
4QQJ
4QQT
4QRC
4R6V
4TYE
4TYG
4TYI
4TYJ
4UXQ
4XCU
5196
5JKG
5NUD
5NWZ
8110265
A_14_P131381
A_23_P92754
AAA63208
AAB59389
AAF27432
AAH11847
AAK51435
AAM13666
ABQ01235
AEO19712
AEO19713
AEO19714
AEO19715
AEO19716
AEO19717
AEO19718
AEO19719
AEO19720
AEO19721
AEO19722
AEO19723
B5A964
CAA40490
CAA74200
CAB005196
CCDS4410
CCDS4411
D6R9V0
D6RG06
D6RJD4
E7EWF4
EAW85036
ENSG00000160867
ENSP00000292408
ENSP00000377254
ENSP00000424960
ENST00000292408
ENST00000393637
ENST00000502906
EntrezGene:2264
FGFR4
FGFR4-201
FGFR4-202
FGFR4-207
g13112051_3p_at
g6739817_3p_a_at
GE57553
GO:0000165
GO:0000166
GO:0001525
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0004888
GO:0005007
GO:0005088
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005737
GO:0005768
GO:0005783
GO:0005794
GO:0005886
GO:0005887
GO:0005911
GO:0006259
GO:0006464
GO:0006468
GO:0006629
GO:0007165
GO:0008150
GO:0008201
GO:0008219
GO:0008283
GO:0008284
GO:0008543
GO:0009058
GO:0009968
GO:0010628
GO:0010715
GO:0016020
GO:0016021
GO:0016301
GO:0016303
GO:0016310
GO:0016477
GO:0016740
GO:0017134
GO:0018108
GO:0019216
GO:0019899
GO:0030133
GO:0030154
GO:0030198
GO:0031410
GO:0032991
GO:0034641
GO:0036092
GO:0040011
GO:0042592
GO:0042593
GO:0042632
GO:0043066
GO:0043085
GO:0043167
GO:0043226
GO:0043235
GO:0043410
GO:0044281
GO:0045862
GO:0046777
GO:0046854
GO:0046934
GO:0048646
GO:0048856
GO:0048870
GO:0051897
GO:0055062
GO:0070374
GO:0070857
GO:2000573
HGNC:3691
HPA027273
HPA027369
HPA028251
ILMN_1730355
ILMN_2241412
ILMN_2410713
IPR000719
IPR001245
IPR003598
IPR003599
IPR007110
IPR008266
IPR011009
IPR013098
IPR013783
IPR016248
IPR017441
IPR020635
IPR036179
J3KPQ0
L03840_s_at
MIM:134935
NM_001354984
NM_002011
NM_022963
NM_213647
NP_001341913
NP_002002
NP_075252
NP_998812
PF07679
PF07714
PF13927
PH_hs_0010000
PR00109
SM00219
SM00408
SM00409
TC05001010.hg
uc003mfl.4
uc003mfm.4
uc003mfo.4
UPI000012A72D
UPI000013E0B8
XM_005265838
XM_011534464
XM_011534465
XP_005265895
Participant Of
hasComponent
Other forms of this molecule
FGFR4 Y367C [plasma membrane]
FGFR4 N535K [plasma membrane]
FGFR4 V550E [plasma membrane]
FGFR4 V550L [plasma membrane]
FGFR4 N535D [plasma membrane]
p-5Y-FGFR4 V550E [plasma membrane]
p-5Y-FGFR4 N535K [plasma membrane]
p-5Y-FGFR4 V550L [plasma membrane]
p-5Y-FGFR4 N535D [plasma membrane]
FGFR4 [plasma membrane]
p-5Y-FGFR4 [plasma membrane]
Modified Residues
Name
L-tyrosine 367 replaced with L-cysteine
Coordinate
367
PsiMod
L-cysteine residue [MOD:00014]
A protein modification that effectively converts a source amino acid residue to an L-cysteine.
L-tyrosine removal [MOD:01649]
A protein modification that effectively removes or replaces an L-tyrosine.
Name
O4'-phospho-L-tyrosine at 642
Coordinate
642
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 643
Coordinate
643
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 719
Coordinate
719
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 754
Coordinate
754
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 764
Coordinate
764
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
breast cancer 1612 malignant tumor of the breast, mammary cancer, malignant neoplasm of breast, mammary tumor, primary breast cancer, breast cancer, Ca breast - NOS, breast tumor
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
PRO
PDB
GeneCards
DOCK Blaster
BRENDA (Homo sapiens)
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein