p-5Y-FGFR4 N535K [plasma membrane]

Stable Identifier
R-HSA-2038931
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
p-5Y-FGFR4 N535K [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
19809159 Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

Taylor JG, 6th, Cheuk, AT, Tsang, PS, Chung, JY, Song, YK, Desai, K, Yu, Y, Chen, QR, Shah, K, Youngblood, V, Fang, J, Kim, S, Yeung, C, Helman, LJ, Mendoza, A, Ngo, V, Staudt, LM, Wei, JS, Khanna, C, Catchpoole, D, Qualman, SJ, Hewitt, SM, Merlino, G, Chanock, SJ, Khan, J

J Clin Invest 2009
External Reference Information
External Reference
Gene Names
FGFR4, JTK2, TKF
Chain
signal peptide:1-21, chain:22-802
Other Identifiers
0000110440
0001090372
0005290176
11735873_a_at
11740240_a_at
11744657_x_at
11752172_a_at
11753528_a_at
11757181_x_at
1291_s_at
1554962_a_at
16992957
204579_at
211237_s_at
2264
2842912
2842913
2842914
2842915
2842916
2842918
2842920
2842922
2842923
2842924
2842926
2842928
2842930
2842931
2842932
2842933
2842934
2842935
2842936
2842938
2842939
2842941
2842943
2842944
8110265
A_14_P131381
A_23_P92754
GE57553
GO:0000165
GO:0000166
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005794
GO:0005886
GO:0005887
GO:0005911
GO:0006259
GO:0006464
GO:0006468
GO:0006629
GO:0007165
GO:0007169
GO:0007275
GO:0008150
GO:0008201
GO:0008283
GO:0008284
GO:0008543
GO:0009058
GO:0010628
GO:0010715
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0017134
GO:0018108
GO:0019216
GO:0030133
GO:0030198
GO:0031410
GO:0032991
GO:0033674
GO:0034641
GO:0040011
GO:0042592
GO:0042593
GO:0042632
GO:0043085
GO:0043167
GO:0043226
GO:0043235
GO:0044281
GO:0045862
GO:0046777
GO:0048856
GO:0048870
GO:0051897
GO:0055062
GO:0070374
GO:0070857
GO:2000573
ILMN_1730355
ILMN_2241412
ILMN_2410713
L03840_s_at
PH_hs_0010000
TC05001010.hg
g13112051_3p_at
g6739817_3p_a_at
Participant Of
Other forms of this molecule
Modified Residues
Name
O4'-phospho-L-tyrosine at 642
Coordinate
642
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 643
Coordinate
643
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 719
Coordinate
719
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 754
Coordinate
754
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 764
Coordinate
764
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
L-asparagine 535 replaced with L-lysine
Coordinate
535
PsiMod
A protein modification that effectively removes or replaces an L-asparagine.
A protein modification that effectively converts a source amino acid residue to L-lysine.
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
rhabdomyosarcoma 3247 Rhabdomyosarcoma NOS (morphologic abnormality), rhabdomyosarcoma, Rhabdomyosarcoma, no subtype (morphologic abnormality), rhabdomyoblastoma, Rhabdomyosarcoma (disorder)
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
GeneCards
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
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