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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
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Advanced Data Search
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Outreach
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GSH [cytosol]
Stable Identifier
R-ALL-29450
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Reduced glutathione, glutathione, 5-L-Glutamyl-L-cysteinylglycine, N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine, gamma-L-Glutamyl-L-cysteinyl-glycine, glutathionate(1-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Detoxification of Reactive Oxygen Species (Bos taurus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Bos taurus)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSH [cytosol]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
GST dimers cleave AZA to 6MP (Bos taurus)
GSH [cytosol]
Paracetamol ADME (Bos taurus)
GSTs transfer GSH to NAPQI to form APAP-SG (Bos taurus)
GSH [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSH [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Bos taurus)
GSH [cytosol]
Biological oxidations (Bos taurus)
Aflatoxin activation and detoxification (Bos taurus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Bos taurus)
GSH [cytosol]
Phase II - Conjugation of compounds (Bos taurus)
Glutathione conjugation (Bos taurus)
GST dimers conjugate GSH with cytosolic substrates (Bos taurus)
GSH [cytosol]
Glutathione synthesis and recycling (Bos taurus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Bos taurus)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Bos taurus)
GSH [cytosol]
Methylation (Bos taurus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Bos taurus)
GSH [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Phenylalanine and tyrosine metabolism (Bos taurus)
Tyrosine catabolism (Bos taurus)
GSTZ1 isomerizes 4-MAA (Bos taurus)
GSTZ1 dimer [cytosol] (Bos taurus)
GSH [cytosol]
Metabolism of lipids (Bos taurus)
Biosynthesis of specialized proresolving mediators (SPMs) (Bos taurus)
Biosynthesis of DHA-derived SPMs (Bos taurus)
Biosynthesis of D-series resolvins (Bos taurus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Bos taurus)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Bos taurus)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Bos taurus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Bos taurus)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Bos taurus)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Bos taurus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Bos taurus)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Bos taurus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Bos taurus)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Bos taurus)
Biosynthesis of E-series 18(R)-resolvins (Bos taurus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Bos taurus)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Bos taurus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Bos taurus)
GSH [cytosol]
Fatty acid metabolism (Bos taurus)
Arachidonate metabolism (Bos taurus)
Synthesis of 12-eicosatetraenoic acid derivatives (Bos taurus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Bos taurus)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Bos taurus)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Bos taurus)
EXA4 is converted to EXC4 by LTC4S (Bos taurus)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Bos taurus)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Bos taurus)
PGH2 is isomerised to PGD2 by HPGDS (Bos taurus)
HPGDS dimer [cytosol] (Bos taurus)
GSH [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Bos taurus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
GSH [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
MMACHC dealkylates RCbl (Bos taurus)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Bos taurus)
GSTO dimers reduce DeHA to AscH- (Bos taurus)
GSH [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
Detoxification of Reactive Oxygen Species (Caenorhabditis elegans)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSH [cytosol]
Drug ADME (Caenorhabditis elegans)
Paracetamol ADME (Caenorhabditis elegans)
GSTs transfer GSH to NAPQI to form APAP-SG (Caenorhabditis elegans)
GSH [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSH [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Glutathione conjugation (Caenorhabditis elegans)
GST dimers conjugate GSH with cytosolic substrates (Caenorhabditis elegans)
GSH [cytosol]
Glutathione synthesis and recycling (Caenorhabditis elegans)
CHAC1,2 cleaves GSH to OPRO and CysGly (Caenorhabditis elegans)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Caenorhabditis elegans)
GSH [cytosol]
Methylation (Caenorhabditis elegans)
GSTO1 dimer reduces methylarsonate to methylarsonite (Caenorhabditis elegans)
GSH [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Phenylalanine and tyrosine metabolism (Caenorhabditis elegans)
Tyrosine catabolism (Caenorhabditis elegans)
GSTZ1 isomerizes 4-MAA (Caenorhabditis elegans)
GSTZ1 dimer [cytosol] (Caenorhabditis elegans)
GSH [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Biosynthesis of specialized proresolving mediators (SPMs) (Caenorhabditis elegans)
Biosynthesis of DHA-derived SPMs (Caenorhabditis elegans)
Biosynthesis of D-series resolvins (Caenorhabditis elegans)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Caenorhabditis elegans)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Caenorhabditis elegans)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Caenorhabditis elegans)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Caenorhabditis elegans)
Biosynthesis of E-series 18(R)-resolvins (Caenorhabditis elegans)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Caenorhabditis elegans)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Caenorhabditis elegans)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Caenorhabditis elegans)
GSH [cytosol]
Fatty acid metabolism (Caenorhabditis elegans)
Arachidonate metabolism (Caenorhabditis elegans)
Synthesis of 12-eicosatetraenoic acid derivatives (Caenorhabditis elegans)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Caenorhabditis elegans)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Caenorhabditis elegans)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Caenorhabditis elegans)
PGH2 is isomerised to PGD2 by HPGDS (Caenorhabditis elegans)
HPGDS dimer [cytosol] (Caenorhabditis elegans)
GSH [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Caenorhabditis elegans)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
GSH [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
MMACHC dealkylates RCbl (Caenorhabditis elegans)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Caenorhabditis elegans)
GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)
GSH [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Detoxification of Reactive Oxygen Species (Canis familiaris)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Canis familiaris)
GSH [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSH [cytosol]
Drug ADME (Canis familiaris)
Azathioprine ADME (Canis familiaris)
GST dimers cleave AZA to 6MP (Canis familiaris)
GSH [cytosol]
Paracetamol ADME (Canis familiaris)
GSTs transfer GSH to NAPQI to form APAP-SG (Canis familiaris)
GSH [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSH [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Canis familiaris)
GSH [cytosol]
Biological oxidations (Canis familiaris)
Aflatoxin activation and detoxification (Canis familiaris)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Canis familiaris)
GSH [cytosol]
Phase II - Conjugation of compounds (Canis familiaris)
Glutathione conjugation (Canis familiaris)
GST dimers conjugate GSH with cytosolic substrates (Canis familiaris)
GSH [cytosol]
Glutathione synthesis and recycling (Canis familiaris)
CHAC1,2 cleaves GSH to OPRO and CysGly (Canis familiaris)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Canis familiaris)
GSH [cytosol]
Methylation (Canis familiaris)
GSTO1 dimer reduces methylarsonate to methylarsonite (Canis familiaris)
GSH [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Phenylalanine and tyrosine metabolism (Canis familiaris)
Tyrosine catabolism (Canis familiaris)
GSTZ1 isomerizes 4-MAA (Canis familiaris)
GSTZ1 dimer [cytosol] (Canis familiaris)
GSH [cytosol]
Metabolism of lipids (Canis familiaris)
Biosynthesis of specialized proresolving mediators (SPMs) (Canis familiaris)
Biosynthesis of DHA-derived SPMs (Canis familiaris)
Biosynthesis of D-series resolvins (Canis familiaris)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Canis familiaris)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Canis familiaris)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Canis familiaris)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Canis familiaris)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Canis familiaris)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Canis familiaris)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Canis familiaris)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Canis familiaris)
Biosynthesis of E-series 18(R)-resolvins (Canis familiaris)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Canis familiaris)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Canis familiaris)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Canis familiaris)
GSH [cytosol]
Fatty acid metabolism (Canis familiaris)
Arachidonate metabolism (Canis familiaris)
Synthesis of 12-eicosatetraenoic acid derivatives (Canis familiaris)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Canis familiaris)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Canis familiaris)
GSH [cytosol]
Synthesis of 15-eicosatetraenoic acid derivatives (Canis familiaris)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Canis familiaris)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Canis familiaris)
EXA4 is converted to EXC4 by LTC4S (Canis familiaris)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Canis familiaris)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Canis familiaris)
PGH2 is isomerised to PGD2 by HPGDS (Canis familiaris)
HPGDS dimer [cytosol] (Canis familiaris)
GSH [cytosol]
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Canis familiaris)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
GSH [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
MMACHC dealkylates RCbl (Canis familiaris)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Canis familiaris)
GSTO dimers reduce DeHA to AscH- (Canis familiaris)
GSH [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Detoxification of Reactive Oxygen Species (Danio rerio)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
GSH [cytosol]
Drug ADME (Danio rerio)
Azathioprine ADME (Danio rerio)
GST dimers cleave AZA to 6MP (Danio rerio)
GSH [cytosol]
Paracetamol ADME (Danio rerio)
GSTs transfer GSH to NAPQI to form APAP-SG (Danio rerio)
GSH [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Danio rerio)
GSH [cytosol]
Biological oxidations (Danio rerio)
Aflatoxin activation and detoxification (Danio rerio)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Danio rerio)
GSH [cytosol]
Phase II - Conjugation of compounds (Danio rerio)
Glutathione conjugation (Danio rerio)
GST dimers conjugate GSH with cytosolic substrates (Danio rerio)
GSH [cytosol]
Glutathione synthesis and recycling (Danio rerio)
CHAC1,2 cleaves GSH to OPRO and CysGly (Danio rerio)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Danio rerio)
GSH [cytosol]
Methylation (Danio rerio)
GSTO1 dimer reduces methylarsonate to methylarsonite (Danio rerio)
GSH [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Phenylalanine and tyrosine metabolism (Danio rerio)
Tyrosine catabolism (Danio rerio)
GSTZ1 isomerizes 4-MAA (Danio rerio)
GSTZ1 dimer [cytosol] (Danio rerio)
GSH [cytosol]
Metabolism of lipids (Danio rerio)
Biosynthesis of specialized proresolving mediators (SPMs) (Danio rerio)
Biosynthesis of DHA-derived SPMs (Danio rerio)
Biosynthesis of DHA-derived sulfido conjugates (Danio rerio)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Danio rerio)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Danio rerio)
GSH [cytosol]
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Danio rerio)
GSH [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Danio rerio)
Cobalamin (Cbl) metabolism (Danio rerio)
MMACHC dealkylates RCbl (Danio rerio)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Danio rerio)
GSTO dimers reduce DeHA to AscH- (Danio rerio)
GSH [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular response to chemical stress (Dictyostelium discoideum)
Detoxification of Reactive Oxygen Species (Dictyostelium discoideum)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Dictyostelium discoideum)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSH [cytosol]
Drug ADME (Dictyostelium discoideum)
Azathioprine ADME (Dictyostelium discoideum)
GST dimers cleave AZA to 6MP (Dictyostelium discoideum)
GSH [cytosol]
Paracetamol ADME (Dictyostelium discoideum)
GSTs transfer GSH to NAPQI to form APAP-SG (Dictyostelium discoideum)
GSH [cytosol]
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSH [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Aflatoxin activation and detoxification (Dictyostelium discoideum)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Dictyostelium discoideum)
GSH [cytosol]
Phase II - Conjugation of compounds (Dictyostelium discoideum)
Glutathione conjugation (Dictyostelium discoideum)
GST dimers conjugate GSH with cytosolic substrates (Dictyostelium discoideum)
GSH [cytosol]
Glutathione synthesis and recycling (Dictyostelium discoideum)
CHAC1,2 cleaves GSH to OPRO and CysGly (Dictyostelium discoideum)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Dictyostelium discoideum)
GSH [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Phenylalanine and tyrosine metabolism (Dictyostelium discoideum)
Tyrosine catabolism (Dictyostelium discoideum)
GSTZ1 isomerizes 4-MAA (Dictyostelium discoideum)
GSTZ1 dimer [cytosol] (Dictyostelium discoideum)
GSH [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Biosynthesis of specialized proresolving mediators (SPMs) (Dictyostelium discoideum)
Biosynthesis of DHA-derived SPMs (Dictyostelium discoideum)
Biosynthesis of DHA-derived sulfido conjugates (Dictyostelium discoideum)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Dictyostelium discoideum)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Dictyostelium discoideum)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Dictyostelium discoideum)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Dictyostelium discoideum)
GSH [cytosol]
Fatty acid metabolism (Dictyostelium discoideum)
Arachidonate metabolism (Dictyostelium discoideum)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Dictyostelium discoideum)
EXA4 is converted to EXC4 by LTC4S (Dictyostelium discoideum)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Dictyostelium discoideum)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Dictyostelium discoideum)
PGH2 is isomerised to PGD2 by HPGDS (Dictyostelium discoideum)
HPGDS dimer [cytosol] (Dictyostelium discoideum)
GSH [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
GSH [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
MMACHC dealkylates RCbl (Dictyostelium discoideum)
GSH [cytosol]
Drug ADME (Drosophila melanogaster)
Paracetamol ADME (Drosophila melanogaster)
GSTs transfer GSH to NAPQI to form APAP-SG (Drosophila melanogaster)
GSH [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Drosophila melanogaster)
GSH [cytosol]
Biological oxidations (Drosophila melanogaster)
Aflatoxin activation and detoxification (Drosophila melanogaster)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Drosophila melanogaster)
GSH [cytosol]
Phase II - Conjugation of compounds (Drosophila melanogaster)
Glutathione conjugation (Drosophila melanogaster)
GST dimers conjugate GSH with cytosolic substrates (Drosophila melanogaster)
GSH [cytosol]
Glutathione synthesis and recycling (Drosophila melanogaster)
CHAC1,2 cleaves GSH to OPRO and CysGly (Drosophila melanogaster)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Drosophila melanogaster)
GSH [cytosol]
Methylation (Drosophila melanogaster)
GSTO1 dimer reduces methylarsonate to methylarsonite (Drosophila melanogaster)
GSH [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Phenylalanine and tyrosine metabolism (Drosophila melanogaster)
Tyrosine catabolism (Drosophila melanogaster)
GSTZ1 isomerizes 4-MAA (Drosophila melanogaster)
GSTZ1 dimer [cytosol] (Drosophila melanogaster)
GSH [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Arachidonate metabolism (Drosophila melanogaster)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Drosophila melanogaster)
PGH2 is isomerised to PGD2 by HPGDS (Drosophila melanogaster)
HPGDS dimer [cytosol] (Drosophila melanogaster)
GSH [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Vitamin C (ascorbate) metabolism (Drosophila melanogaster)
GSTO dimers reduce DeHA to AscH- (Drosophila melanogaster)
GSH [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Detoxification of Reactive Oxygen Species (Gallus gallus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSH [cytosol]
Drug ADME (Gallus gallus)
Azathioprine ADME (Gallus gallus)
GST dimers cleave AZA to 6MP (Gallus gallus)
GSH [cytosol]
Paracetamol ADME (Gallus gallus)
GSTs transfer GSH to NAPQI to form APAP-SG (Gallus gallus)
GSH [cytosol]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSH [cytosol]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Pyruvate metabolism (Gallus gallus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Gallus gallus)
GSH [cytosol]
Biological oxidations (Gallus gallus)
Aflatoxin activation and detoxification (Gallus gallus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Gallus gallus)
GSH [cytosol]
Phase II - Conjugation of compounds (Gallus gallus)
Glutathione conjugation (Gallus gallus)
GST dimers conjugate GSH with cytosolic substrates (Gallus gallus)
GSH [cytosol]
Glutathione synthesis and recycling (Gallus gallus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Gallus gallus)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Gallus gallus)
GSH [cytosol]
Methylation (Gallus gallus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Gallus gallus)
GSH [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Phenylalanine and tyrosine metabolism (Gallus gallus)
Tyrosine catabolism (Gallus gallus)
GSTZ1 isomerizes 4-MAA (Gallus gallus)
GSTZ1 dimer [cytosol] (Gallus gallus)
GSH [cytosol]
Metabolism of lipids (Gallus gallus)
Biosynthesis of specialized proresolving mediators (SPMs) (Gallus gallus)
Biosynthesis of DHA-derived SPMs (Gallus gallus)
Biosynthesis of D-series resolvins (Gallus gallus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Gallus gallus)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Gallus gallus)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Gallus gallus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Gallus gallus)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Gallus gallus)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Gallus gallus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Gallus gallus)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Gallus gallus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Gallus gallus)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Gallus gallus)
Biosynthesis of E-series 18(R)-resolvins (Gallus gallus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Gallus gallus)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Gallus gallus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Gallus gallus)
GSH [cytosol]
Fatty acid metabolism (Gallus gallus)
Arachidonate metabolism (Gallus gallus)
Synthesis of 12-eicosatetraenoic acid derivatives (Gallus gallus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Gallus gallus)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Gallus gallus)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Gallus gallus)
EXA4 is converted to EXC4 by LTC4S (Gallus gallus)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Gallus gallus)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Gallus gallus)
PGH2 is isomerised to PGD2 by HPGDS (Gallus gallus)
HPGDS dimer [cytosol] (Gallus gallus)
GSH [cytosol]
Metabolism of nucleotides (Gallus gallus)
Interconversion of nucleotide di- and triphosphates (Gallus gallus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Gallus gallus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
GSH [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Cobalamin (Cbl) metabolism (Gallus gallus)
MMACHC dealkylates RCbl (Gallus gallus)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Gallus gallus)
GSTO dimers reduce DeHA to AscH- (Gallus gallus)
GSH [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Detoxification of Reactive Oxygen Species (Homo sapiens)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Homo sapiens)
GSH [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
GSH [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)
Glutathione is taken up by the bacterium (Homo sapiens)
GSH [cytosol]
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
GST dimers cleave AZA to 6MP (Homo sapiens)
GSH [cytosol]
Paracetamol ADME (Homo sapiens)
GSTs transfer GSH to NAPQI to form APAP-SG (Homo sapiens)
GSH [cytosol]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
GSH [cytosol]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Glutathione scavenges nitrosyl (Homo sapiens)
GSH [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Homo sapiens)
GSH [cytosol]
Biological oxidations (Homo sapiens)
Aflatoxin activation and detoxification (Homo sapiens)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Homo sapiens)
GSH [cytosol]
Phase II - Conjugation of compounds (Homo sapiens)
Glutathione conjugation (Homo sapiens)
GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)
GSH [cytosol]
Glutathione synthesis and recycling (Homo sapiens)
CHAC1,2 cleaves GSH to OPRO and CysGly (Homo sapiens)
GSH [cytosol]
GSH translocates from cytosol to extracellular region (Homo sapiens)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Homo sapiens)
GSH [cytosol]
Methylation (Homo sapiens)
GSTO1 dimer reduces methylarsonate to methylarsonite (Homo sapiens)
GSH [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Phenylalanine and tyrosine metabolism (Homo sapiens)
Tyrosine catabolism (Homo sapiens)
GSTZ1 isomerizes 4-MAA (Homo sapiens)
GSTZ1 dimer [cytosol] (Homo sapiens)
GSH [cytosol]
Selenoamino acid metabolism (Homo sapiens)
Formation of selenosugars for excretion (Homo sapiens)
GSSebGalNac is reduced and methylated to MeSebGalNac (Homo sapiens)
GSH [cytosol]
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se (Homo sapiens)
GSSeH condenses with GSH to form H2Se and GSSG (Homo sapiens)
GSH [cytosol]
GSSeSG is reduced to GSSeH and GSH by GSR (Homo sapiens)
GSH [cytosol]
SeO3(2-) combines with GSH to form GSSeSG and GSSG (Homo sapiens)
GSH [cytosol]
Metabolism of lipids (Homo sapiens)
Biosynthesis of specialized proresolving mediators (SPMs) (Homo sapiens)
Biosynthesis of DHA-derived SPMs (Homo sapiens)
Biosynthesis of D-series resolvins (Homo sapiens)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Homo sapiens)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Homo sapiens)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Homo sapiens)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Homo sapiens)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Homo sapiens)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Homo sapiens)
GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 (Homo sapiens)
GSH [cytosol]
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Homo sapiens)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Homo sapiens)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Homo sapiens)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Homo sapiens)
Biosynthesis of E-series 18(R)-resolvins (Homo sapiens)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Homo sapiens)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Homo sapiens)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Homo sapiens)
GSH [cytosol]
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of 12-eicosatetraenoic acid derivatives (Homo sapiens)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Homo sapiens)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Homo sapiens)
GSH [cytosol]
Synthesis of 15-eicosatetraenoic acid derivatives (Homo sapiens)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Homo sapiens)
GSH [cytosol]
Synthesis of 5-eicosatetraenoic acids (Homo sapiens)
5S-HpETE is reduced to 5S-HETE by GPX1/2/4 (Homo sapiens)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Homo sapiens)
EXA4 is converted to EXC4 by LTC4S (Homo sapiens)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Homo sapiens)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Homo sapiens)
PGH2 is isomerised to PGD2 by HPGDS (Homo sapiens)
HPGDS dimer [cytosol] (Homo sapiens)
GSH [cytosol]
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Homo sapiens)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
GSH [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
MMACHC dealkylates RCbl (Homo sapiens)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Homo sapiens)
GSTO dimers reduce DeHA to AscH- (Homo sapiens)
GSH [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Detoxification of Reactive Oxygen Species (Mus musculus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Mus musculus)
GSH [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSH [cytosol]
Drug ADME (Mus musculus)
Azathioprine ADME (Mus musculus)
GST dimers cleave AZA to 6MP (Mus musculus)
GSH [cytosol]
Paracetamol ADME (Mus musculus)
GSTs transfer GSH to NAPQI to form APAP-SG (Mus musculus)
GSH [cytosol]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSH [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Mus musculus)
GSH [cytosol]
Biological oxidations (Mus musculus)
Aflatoxin activation and detoxification (Mus musculus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Mus musculus)
GSH [cytosol]
Phase II - Conjugation of compounds (Mus musculus)
Glutathione conjugation (Mus musculus)
GST dimers conjugate GSH with cytosolic substrates (Mus musculus)
GSH [cytosol]
Glutathione synthesis and recycling (Mus musculus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Mus musculus)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Mus musculus)
GSH [cytosol]
Methylation (Mus musculus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Mus musculus)
GSH [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Phenylalanine and tyrosine metabolism (Mus musculus)
Tyrosine catabolism (Mus musculus)
GSTZ1 isomerizes 4-MAA (Mus musculus)
GSTZ1 dimer [cytosol] (Mus musculus)
GSH [cytosol]
Metabolism of lipids (Mus musculus)
Biosynthesis of specialized proresolving mediators (SPMs) (Mus musculus)
Biosynthesis of DHA-derived SPMs (Mus musculus)
Biosynthesis of D-series resolvins (Mus musculus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Mus musculus)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Mus musculus)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Mus musculus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Mus musculus)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Mus musculus)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Mus musculus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Mus musculus)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Mus musculus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Mus musculus)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Mus musculus)
Biosynthesis of E-series 18(R)-resolvins (Mus musculus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Mus musculus)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Mus musculus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Mus musculus)
GSH [cytosol]
Fatty acid metabolism (Mus musculus)
Arachidonate metabolism (Mus musculus)
Synthesis of 12-eicosatetraenoic acid derivatives (Mus musculus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Mus musculus)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Mus musculus)
GSH [cytosol]
Synthesis of 15-eicosatetraenoic acid derivatives (Mus musculus)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Mus musculus)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Mus musculus)
EXA4 is converted to EXC4 by LTC4S (Mus musculus)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Mus musculus)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Mus musculus)
PGH2 is isomerised to PGD2 by HPGDS (Mus musculus)
HPGDS dimer [cytosol] (Mus musculus)
GSH [cytosol]
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Mus musculus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
GSH [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
MMACHC dealkylates RCbl (Mus musculus)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Mus musculus)
GSTO dimers reduce DeHA to AscH- (Mus musculus)
GSH [cytosol]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
Cellular response to chemical stress (Plasmodium falciparum)
Detoxification of Reactive Oxygen Species (Plasmodium falciparum)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Plasmodium falciparum)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSH [cytosol]
Drug ADME (Plasmodium falciparum)
Azathioprine ADME (Plasmodium falciparum)
GST dimers cleave AZA to 6MP (Plasmodium falciparum)
GSH [cytosol]
Paracetamol ADME (Plasmodium falciparum)
GSTs transfer GSH to NAPQI to form APAP-SG (Plasmodium falciparum)
GSH [cytosol]
Gene expression (Transcription) (Plasmodium falciparum)
RNA Polymerase II Transcription (Plasmodium falciparum)
Generic Transcription Pathway (Plasmodium falciparum)
Transcriptional Regulation by TP53 (Plasmodium falciparum)
TP53 Regulates Metabolic Genes (Plasmodium falciparum)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSH [cytosol]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism (Plasmodium falciparum)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Plasmodium falciparum)
GSH [cytosol]
Biological oxidations (Plasmodium falciparum)
Phase II - Conjugation of compounds (Plasmodium falciparum)
Glutathione conjugation (Plasmodium falciparum)
GST dimers conjugate GSH with cytosolic substrates (Plasmodium falciparum)
GSH [cytosol]
Glutathione synthesis and recycling (Plasmodium falciparum)
GSS:Mg2+ dimer synthesizes GSH (Plasmodium falciparum)
GSH [cytosol]
Metabolism of lipids (Plasmodium falciparum)
Biosynthesis of specialized proresolving mediators (SPMs) (Plasmodium falciparum)
Biosynthesis of DHA-derived SPMs (Plasmodium falciparum)
Biosynthesis of D-series resolvins (Plasmodium falciparum)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Plasmodium falciparum)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Plasmodium falciparum)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Plasmodium falciparum)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Plasmodium falciparum)
Biosynthesis of E-series 18(R)-resolvins (Plasmodium falciparum)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Plasmodium falciparum)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Plasmodium falciparum)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Plasmodium falciparum)
GSH [cytosol]
Fatty acid metabolism (Plasmodium falciparum)
Arachidonate metabolism (Plasmodium falciparum)
Synthesis of 12-eicosatetraenoic acid derivatives (Plasmodium falciparum)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Plasmodium falciparum)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Plasmodium falciparum)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Plasmodium falciparum)
PGH2 is isomerised to PGD2 by HPGDS (Plasmodium falciparum)
HPGDS dimer [cytosol] (Plasmodium falciparum)
GSH [cytosol]
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Plasmodium falciparum)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
GSH [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Rattus norvegicus)
GSH [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSH [cytosol]
Drug ADME (Rattus norvegicus)
Azathioprine ADME (Rattus norvegicus)
GST dimers cleave AZA to 6MP (Rattus norvegicus)
GSH [cytosol]
Paracetamol ADME (Rattus norvegicus)
GSTs transfer GSH to NAPQI to form APAP-SG (Rattus norvegicus)
GSH [cytosol]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSH [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Rattus norvegicus)
GSH [cytosol]
Biological oxidations (Rattus norvegicus)
Aflatoxin activation and detoxification (Rattus norvegicus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Rattus norvegicus)
GSH [cytosol]
Phase II - Conjugation of compounds (Rattus norvegicus)
Glutathione conjugation (Rattus norvegicus)
GST dimers conjugate GSH with cytosolic substrates (Rattus norvegicus)
GSH [cytosol]
Glutathione synthesis and recycling (Rattus norvegicus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Rattus norvegicus)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Rattus norvegicus)
GSH [cytosol]
Methylation (Rattus norvegicus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Rattus norvegicus)
GSH [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Phenylalanine and tyrosine metabolism (Rattus norvegicus)
Tyrosine catabolism (Rattus norvegicus)
GSTZ1 isomerizes 4-MAA (Rattus norvegicus)
GSTZ1 dimer [cytosol] (Rattus norvegicus)
GSH [cytosol]
Metabolism of lipids (Rattus norvegicus)
Biosynthesis of specialized proresolving mediators (SPMs) (Rattus norvegicus)
Biosynthesis of DHA-derived SPMs (Rattus norvegicus)
Biosynthesis of D-series resolvins (Rattus norvegicus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Rattus norvegicus)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Rattus norvegicus)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Rattus norvegicus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Rattus norvegicus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Rattus norvegicus)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Rattus norvegicus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Rattus norvegicus)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Rattus norvegicus)
Biosynthesis of E-series 18(R)-resolvins (Rattus norvegicus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Rattus norvegicus)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Rattus norvegicus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Rattus norvegicus)
GSH [cytosol]
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of 12-eicosatetraenoic acid derivatives (Rattus norvegicus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Rattus norvegicus)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Rattus norvegicus)
GSH [cytosol]
Synthesis of 15-eicosatetraenoic acid derivatives (Rattus norvegicus)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Rattus norvegicus)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Rattus norvegicus)
EXA4 is converted to EXC4 by LTC4S (Rattus norvegicus)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Rattus norvegicus)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
PGH2 is isomerised to PGD2 by HPGDS (Rattus norvegicus)
HPGDS dimer [cytosol] (Rattus norvegicus)
GSH [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Rattus norvegicus)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
GSH [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
MMACHC dealkylates RCbl (Rattus norvegicus)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Rattus norvegicus)
GSTO dimers reduce DeHA to AscH- (Rattus norvegicus)
GSH [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
Detoxification of Reactive Oxygen Species (Saccharomyces cerevisiae)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSH [cytosol]
Gene expression (Transcription) (Saccharomyces cerevisiae)
RNA Polymerase II Transcription (Saccharomyces cerevisiae)
Generic Transcription Pathway (Saccharomyces cerevisiae)
Transcriptional Regulation by TP53 (Saccharomyces cerevisiae)
TP53 Regulates Metabolic Genes (Saccharomyces cerevisiae)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSH [cytosol]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Saccharomyces cerevisiae)
GSH [cytosol]
Biological oxidations (Saccharomyces cerevisiae)
Phase II - Conjugation of compounds (Saccharomyces cerevisiae)
Glutathione conjugation (Saccharomyces cerevisiae)
Glutathione synthesis and recycling (Saccharomyces cerevisiae)
CHAC1,2 cleaves GSH to OPRO and CysGly (Saccharomyces cerevisiae)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)
GSH [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
GSH [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
Detoxification of Reactive Oxygen Species (Schizosaccharomyces pombe)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSH [cytosol]
Gene expression (Transcription) (Schizosaccharomyces pombe)
RNA Polymerase II Transcription (Schizosaccharomyces pombe)
Generic Transcription Pathway (Schizosaccharomyces pombe)
Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
TP53 Regulates Metabolic Genes (Schizosaccharomyces pombe)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSH [cytosol]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Schizosaccharomyces pombe)
GSH [cytosol]
Biological oxidations (Schizosaccharomyces pombe)
Phase II - Conjugation of compounds (Schizosaccharomyces pombe)
Glutathione conjugation (Schizosaccharomyces pombe)
Glutathione synthesis and recycling (Schizosaccharomyces pombe)
CHAC1,2 cleaves GSH to OPRO and CysGly (Schizosaccharomyces pombe)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Schizosaccharomyces pombe)
GSH [cytosol]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
GSH [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Detoxification of Reactive Oxygen Species (Sus scrofa)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Sus scrofa)
GSH [cytosol]
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GSH [cytosol]
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSH [cytosol]
Drug ADME (Sus scrofa)
Azathioprine ADME (Sus scrofa)
GST dimers cleave AZA to 6MP (Sus scrofa)
GSH [cytosol]
Paracetamol ADME (Sus scrofa)
GSTs transfer GSH to NAPQI to form APAP-SG (Sus scrofa)
GSH [cytosol]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSH [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Sus scrofa)
GSH [cytosol]
Biological oxidations (Sus scrofa)
Aflatoxin activation and detoxification (Sus scrofa)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Sus scrofa)
GSH [cytosol]
Phase II - Conjugation of compounds (Sus scrofa)
Glutathione conjugation (Sus scrofa)
GST dimers conjugate GSH with cytosolic substrates (Sus scrofa)
GSH [cytosol]
Glutathione synthesis and recycling (Sus scrofa)
CHAC1,2 cleaves GSH to OPRO and CysGly (Sus scrofa)
GSH [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Sus scrofa)
GSH [cytosol]
Methylation (Sus scrofa)
GSTO1 dimer reduces methylarsonate to methylarsonite (Sus scrofa)
GSH [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Phenylalanine and tyrosine metabolism (Sus scrofa)
Tyrosine catabolism (Sus scrofa)
GSTZ1 isomerizes 4-MAA (Sus scrofa)
GSTZ1 dimer [cytosol] (Sus scrofa)
GSH [cytosol]
Metabolism of lipids (Sus scrofa)
Biosynthesis of specialized proresolving mediators (SPMs) (Sus scrofa)
Biosynthesis of DHA-derived SPMs (Sus scrofa)
Biosynthesis of D-series resolvins (Sus scrofa)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Sus scrofa)
GSH [cytosol]
Biosynthesis of DHA-derived sulfido conjugates (Sus scrofa)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Sus scrofa)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Sus scrofa)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Sus scrofa)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Sus scrofa)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Sus scrofa)
GSH [cytosol]
Biosynthesis of aspirin-triggered D-series resolvins (Sus scrofa)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Sus scrofa)
GSH [cytosol]
Biosynthesis of EPA-derived SPMs (Sus scrofa)
Biosynthesis of E-series 18(R)-resolvins (Sus scrofa)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Sus scrofa)
GSH [cytosol]
Biosynthesis of E-series 18(S)-resolvins (Sus scrofa)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Sus scrofa)
GSH [cytosol]
Fatty acid metabolism (Sus scrofa)
Arachidonate metabolism (Sus scrofa)
Synthesis of 12-eicosatetraenoic acid derivatives (Sus scrofa)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Sus scrofa)
GSH [cytosol]
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Sus scrofa)
GSH [cytosol]
Synthesis of 15-eicosatetraenoic acid derivatives (Sus scrofa)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Sus scrofa)
GSH [cytosol]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Sus scrofa)
EXA4 is converted to EXC4 by LTC4S (Sus scrofa)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Sus scrofa)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Sus scrofa)
PGH2 is isomerised to PGD2 by HPGDS (Sus scrofa)
HPGDS dimer [cytosol] (Sus scrofa)
GSH [cytosol]
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Sus scrofa)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
GSH [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Cobalamin (Cbl) metabolism (Sus scrofa)
MMACHC dealkylates RCbl (Sus scrofa)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Sus scrofa)
GSTO dimers reduce DeHA to AscH- (Sus scrofa)
GSH [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSH [cytosol]
Drug ADME (Xenopus tropicalis)
Azathioprine ADME (Xenopus tropicalis)
GST dimers cleave AZA to 6MP (Xenopus tropicalis)
GSH [cytosol]
Paracetamol ADME (Xenopus tropicalis)
GSTs transfer GSH to NAPQI to form APAP-SG (Xenopus tropicalis)
GSH [cytosol]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
TP53 Regulates Metabolic Genes (Xenopus tropicalis)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSH [cytosol]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Xenopus tropicalis)
GSH [cytosol]
Biological oxidations (Xenopus tropicalis)
Aflatoxin activation and detoxification (Xenopus tropicalis)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Xenopus tropicalis)
GSH [cytosol]
Phase II - Conjugation of compounds (Xenopus tropicalis)
Glutathione conjugation (Xenopus tropicalis)
GST dimers conjugate GSH with cytosolic substrates (Xenopus tropicalis)
GSH [cytosol]
Glutathione synthesis and recycling (Xenopus tropicalis)
CHAC1,2 cleaves GSH to OPRO and CysGly (Xenopus tropicalis)
GSH [cytosol]
Methylation (Xenopus tropicalis)
GSTO1 dimer reduces methylarsonate to methylarsonite (Xenopus tropicalis)
GSH [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Phenylalanine and tyrosine metabolism (Xenopus tropicalis)
Tyrosine catabolism (Xenopus tropicalis)
GSTZ1 isomerizes 4-MAA (Xenopus tropicalis)
GSTZ1 dimer [cytosol] (Xenopus tropicalis)
GSH [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Biosynthesis of specialized proresolving mediators (SPMs) (Xenopus tropicalis)
Biosynthesis of DHA-derived SPMs (Xenopus tropicalis)
Biosynthesis of DHA-derived sulfido conjugates (Xenopus tropicalis)
Biosynthesis of maresin conjugates in tissue regeneration (MCTR) (Xenopus tropicalis)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Xenopus tropicalis)
GSH [cytosol]
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Xenopus tropicalis)
GSH [cytosol]
Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) (Xenopus tropicalis)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Xenopus tropicalis)
GSH [cytosol]
Fatty acid metabolism (Xenopus tropicalis)
Arachidonate metabolism (Xenopus tropicalis)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Xenopus tropicalis)
EXA4 is converted to EXC4 by LTC4S (Xenopus tropicalis)
GSH [cytosol]
LTA4 is converted to LTC4 by LTC4S (Xenopus tropicalis)
GSH [cytosol]
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Xenopus tropicalis)
PGH2 is isomerised to PGD2 by HPGDS (Xenopus tropicalis)
HPGDS dimer [cytosol] (Xenopus tropicalis)
GSH [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Xenopus tropicalis)
GSH [cytosol]
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
GSH [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Xenopus tropicalis)
Cobalamin (Cbl) metabolism (Xenopus tropicalis)
MMACHC dealkylates RCbl (Xenopus tropicalis)
GSH [cytosol]
Vitamin C (ascorbate) metabolism (Xenopus tropicalis)
GSTO dimers reduce DeHA to AscH- (Xenopus tropicalis)
GSH [cytosol]
External Reference Information
External Reference
glutathionate(1-) [ChEBI:57925]
Participates
as a component of
HPGDS dimer [cytosol] (Bos taurus)
HPGDS dimer [cytosol] (Rattus norvegicus)
HPGDS dimer [cytosol] (Gallus gallus)
HPGDS dimer [cytosol] (Xenopus tropicalis)
HPGDS dimer [cytosol] (Plasmodium falciparum)
HPGDS dimer [cytosol] (Sus scrofa)
HPGDS dimer [cytosol] (Dictyostelium discoideum)
HPGDS dimer [cytosol] (Caenorhabditis elegans)
HPGDS dimer [cytosol] (Canis familiaris)
HPGDS dimer [cytosol] (Drosophila melanogaster)
HPGDS dimer [cytosol] (Mus musculus)
HPGDS dimer [cytosol] (Homo sapiens)
GSTZ1 dimer [cytosol] (Dictyostelium discoideum)
GSTZ1 dimer [cytosol] (Drosophila melanogaster)
GSTZ1 dimer [cytosol] (Xenopus tropicalis)
GSTZ1 dimer [cytosol] (Bos taurus)
GSTZ1 dimer [cytosol] (Rattus norvegicus)
GSTZ1 dimer [cytosol] (Gallus gallus)
GSTZ1 dimer [cytosol] (Mus musculus)
GSTZ1 dimer [cytosol] (Sus scrofa)
GSTZ1 dimer [cytosol] (Caenorhabditis elegans)
GSTZ1 dimer [cytosol] (Danio rerio)
GSTZ1 dimer [cytosol] (Homo sapiens)
GSTZ1 dimer [cytosol] (Canis familiaris)
as an input of
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Plasmodium falciparum)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Caenorhabditis elegans)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Gallus gallus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Sus scrofa)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Bos taurus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Canis familiaris)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Rattus norvegicus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Mus musculus)
GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Homo sapiens)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Dictyostelium discoideum)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Gallus gallus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Xenopus tropicalis)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Sus scrofa)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Bos taurus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Canis familiaris)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Rattus norvegicus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Mus musculus)
LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Homo sapiens)
GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1 (Homo sapiens)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Dictyostelium discoideum)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Gallus gallus)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Xenopus tropicalis)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Sus scrofa)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Bos taurus)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Mus musculus)
LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Homo sapiens)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Gallus gallus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Xenopus tropicalis)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Danio rerio)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Sus scrofa)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Bos taurus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Mus musculus)
GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Homo sapiens)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Plasmodium falciparum)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Caenorhabditis elegans)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Gallus gallus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Sus scrofa)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Bos taurus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Canis familiaris)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Rattus norvegicus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Mus musculus)
GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Homo sapiens)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Plasmodium falciparum)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Caenorhabditis elegans)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Gallus gallus)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Sus scrofa)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Bos taurus)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Canis familiaris)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Rattus norvegicus)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Mus musculus)
12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Homo sapiens)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Plasmodium falciparum)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Caenorhabditis elegans)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Gallus gallus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Sus scrofa)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Bos taurus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Canis familiaris)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Rattus norvegicus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Mus musculus)
12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Homo sapiens)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Sus scrofa)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Canis familiaris)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Rattus norvegicus)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Mus musculus)
15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Homo sapiens)
EXA4 is converted to EXC4 by LTC4S (Dictyostelium discoideum)
EXA4 is converted to EXC4 by LTC4S (Gallus gallus)
EXA4 is converted to EXC4 by LTC4S (Xenopus tropicalis)
EXA4 is converted to EXC4 by LTC4S (Sus scrofa)
EXA4 is converted to EXC4 by LTC4S (Bos taurus)
EXA4 is converted to EXC4 by LTC4S (Canis familiaris)
EXA4 is converted to EXC4 by LTC4S (Rattus norvegicus)
EXA4 is converted to EXC4 by LTC4S (Mus musculus)
EXA4 is converted to EXC4 by LTC4S (Homo sapiens)
5S-HpETE is reduced to 5S-HETE by GPX1 (Oryctolagus cuniculus)
5S-HpETE is reduced to 5S-HETE by GPX1/2/4 (Homo sapiens)
GST dimers cleave AZA to 6MP (Plasmodium falciparum)
GST dimers cleave AZA to 6MP (Dictyostelium discoideum)
GST dimers cleave AZA to 6MP (Gallus gallus)
GST dimers cleave AZA to 6MP (Xenopus tropicalis)
GST dimers cleave AZA to 6MP (Danio rerio)
GST dimers cleave AZA to 6MP (Sus scrofa)
GST dimers cleave AZA to 6MP (Bos taurus)
GST dimers cleave AZA to 6MP (Canis familiaris)
GST dimers cleave AZA to 6MP (Rattus norvegicus)
GST dimers cleave AZA to 6MP (Mus musculus)
GST dimers cleave AZA to 6MP (Homo sapiens)
GSTs transfer GSH to NAPQI to form APAP-SG (Plasmodium falciparum)
GSTs transfer GSH to NAPQI to form APAP-SG (Dictyostelium discoideum)
GSTs transfer GSH to NAPQI to form APAP-SG (Caenorhabditis elegans)
GSTs transfer GSH to NAPQI to form APAP-SG (Drosophila melanogaster)
GSTs transfer GSH to NAPQI to form APAP-SG (Gallus gallus)
GSTs transfer GSH to NAPQI to form APAP-SG (Xenopus tropicalis)
GSTs transfer GSH to NAPQI to form APAP-SG (Danio rerio)
GSTs transfer GSH to NAPQI to form APAP-SG (Sus scrofa)
GSTs transfer GSH to NAPQI to form APAP-SG (Bos taurus)
GSTs transfer GSH to NAPQI to form APAP-SG (Canis familiaris)
GSTs transfer GSH to NAPQI to form APAP-SG (Rattus norvegicus)
GSTs transfer GSH to NAPQI to form APAP-SG (Mus musculus)
GSTs transfer GSH to NAPQI to form APAP-SG (Homo sapiens)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Dictyostelium discoideum)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Drosophila melanogaster)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Gallus gallus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Xenopus tropicalis)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Danio rerio)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Sus scrofa)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Bos taurus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Canis familiaris)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Rattus norvegicus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Mus musculus)
MGST trimers transfer GS from GSH to AFXBO and AFNBO (Homo sapiens)
LTA4 is converted to LTC4 by LTC4S (Dictyostelium discoideum)
LTA4 is converted to LTC4 by LTC4S (Gallus gallus)
LTA4 is converted to LTC4 by LTC4S (Xenopus tropicalis)
LTA4 is converted to LTC4 by LTC4S (Sus scrofa)
LTA4 is converted to LTC4 by LTC4S (Bos taurus)
LTA4 is converted to LTC4 by LTC4S (Canis familiaris)
LTA4 is converted to LTC4 by LTC4S (Rattus norvegicus)
LTA4 is converted to LTC4 by LTC4S (Mus musculus)
LTA4 is converted to LTC4 by LTC4S (Homo sapiens)
GST dimers conjugate GSH with cytosolic substrates (Plasmodium falciparum)
GST dimers conjugate GSH with cytosolic substrates (Dictyostelium discoideum)
GST dimers conjugate GSH with cytosolic substrates (Caenorhabditis elegans)
GST dimers conjugate GSH with cytosolic substrates (Drosophila melanogaster)
GST dimers conjugate GSH with cytosolic substrates (Gallus gallus)
GST dimers conjugate GSH with cytosolic substrates (Xenopus tropicalis)
GST dimers conjugate GSH with cytosolic substrates (Danio rerio)
GST dimers conjugate GSH with cytosolic substrates (Sus scrofa)
GST dimers conjugate GSH with cytosolic substrates (Bos taurus)
GST dimers conjugate GSH with cytosolic substrates (Canis familiaris)
GST dimers conjugate GSH with cytosolic substrates (Rattus norvegicus)
GST dimers conjugate GSH with cytosolic substrates (Mus musculus)
GST dimers conjugate GSH with cytosolic substrates (Homo sapiens)
CHAC1,2 cleaves GSH to OPRO and CysGly (Gallus gallus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Saccharomyces cerevisiae)
CHAC1,2 cleaves GSH to OPRO and CysGly (Schizosaccharomyces pombe)
CHAC1,2 cleaves GSH to OPRO and CysGly (Dictyostelium discoideum)
CHAC1,2 cleaves GSH to OPRO and CysGly (Caenorhabditis elegans)
CHAC1,2 cleaves GSH to OPRO and CysGly (Drosophila melanogaster)
CHAC1,2 cleaves GSH to OPRO and CysGly (Xenopus tropicalis)
CHAC1,2 cleaves GSH to OPRO and CysGly (Danio rerio)
CHAC1,2 cleaves GSH to OPRO and CysGly (Sus scrofa)
CHAC1,2 cleaves GSH to OPRO and CysGly (Bos taurus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Canis familiaris)
CHAC1,2 cleaves GSH to OPRO and CysGly (Rattus norvegicus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Mus musculus)
CHAC1,2 cleaves GSH to OPRO and CysGly (Homo sapiens)
GSH translocates from cytosol to extracellular region (Homo sapiens)
GSTO1 dimer reduces methylarsonate to methylarsonite (Caenorhabditis elegans)
GSTO1 dimer reduces methylarsonate to methylarsonite (Drosophila melanogaster)
GSTO1 dimer reduces methylarsonate to methylarsonite (Gallus gallus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Xenopus tropicalis)
GSTO1 dimer reduces methylarsonate to methylarsonite (Danio rerio)
GSTO1 dimer reduces methylarsonate to methylarsonite (Sus scrofa)
GSTO1 dimer reduces methylarsonate to methylarsonite (Bos taurus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Canis familiaris)
GSTO1 dimer reduces methylarsonate to methylarsonite (Rattus norvegicus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Mus musculus)
GSTO1 dimer reduces methylarsonate to methylarsonite (Homo sapiens)
Glutathione is taken up by the bacterium (Homo sapiens)
GSSeH condenses with GSH to form H2Se and GSSG (Rattus norvegicus)
GSSeH condenses with GSH to form H2Se and GSSG (Homo sapiens)
SeO3(2-) combines with GSH to form GSSeSG and GSSG (Rattus norvegicus)
SeO3(2-) combines with GSH to form GSSeSG and GSSG (Homo sapiens)
Glutathione scavenges nitrosyl (Homo sapiens)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Plasmodium falciparum)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Caenorhabditis elegans)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Gallus gallus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Sus scrofa)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Bos taurus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Canis familiaris)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Rattus norvegicus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Mus musculus)
GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Homo sapiens)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Plasmodium falciparum)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Caenorhabditis elegans)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Gallus gallus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Sus scrofa)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Bos taurus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Canis familiaris)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Rattus norvegicus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Mus musculus)
GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Homo sapiens)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Sus scrofa)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Bos taurus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Canis familiaris)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Rattus norvegicus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Mus musculus)
GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Homo sapiens)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Plasmodium falciparum)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Dictyostelium discoideum)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Xenopus tropicalis)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Bos taurus)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Plasmodium falciparum)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Saccharomyces cerevisiae)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Schizosaccharomyces pombe)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Drosophila melanogaster)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Gallus gallus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Xenopus tropicalis)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Danio rerio)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Sus scrofa)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Bos taurus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Canis familiaris)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Rattus norvegicus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Mus musculus)
GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Homo sapiens)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Sus scrofa)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)
GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)
MMACHC dealkylates RCbl (Homo sapiens)
MMACHC dealkylates RCbl (Mus musculus)
MMACHC dealkylates RCbl (Rattus norvegicus)
MMACHC dealkylates RCbl (Canis familiaris)
MMACHC dealkylates RCbl (Bos taurus)
MMACHC dealkylates RCbl (Sus scrofa)
MMACHC dealkylates RCbl (Danio rerio)
MMACHC dealkylates RCbl (Xenopus tropicalis)
MMACHC dealkylates RCbl (Gallus gallus)
MMACHC dealkylates RCbl (Caenorhabditis elegans)
MMACHC dealkylates RCbl (Dictyostelium discoideum)
GSTO dimers reduce DeHA to AscH- (Mus musculus)
GSTO dimers reduce DeHA to AscH- (Homo sapiens)
GSTO dimers reduce DeHA to AscH- (Rattus norvegicus)
GSTO dimers reduce DeHA to AscH- (Canis familiaris)
GSTO dimers reduce DeHA to AscH- (Bos taurus)
GSTO dimers reduce DeHA to AscH- (Sus scrofa)
GSTO dimers reduce DeHA to AscH- (Danio rerio)
GSTO dimers reduce DeHA to AscH- (Xenopus tropicalis)
GSTO dimers reduce DeHA to AscH- (Gallus gallus)
GSTO dimers reduce DeHA to AscH- (Drosophila melanogaster)
GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Mus musculus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Homo sapiens)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Rattus norvegicus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Canis familiaris)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Bos taurus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Sus scrofa)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Danio rerio)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Xenopus tropicalis)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Gallus gallus)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Caenorhabditis elegans)
glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Plasmodium falciparum)
as an output of
GSS:Mg2+ dimer synthesizes GSH (Plasmodium falciparum)
GSS:Mg2+ dimer synthesizes GSH (Gallus gallus)
GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)
GSS:Mg2+ dimer synthesizes GSH (Schizosaccharomyces pombe)
GSS:Mg2+ dimer synthesizes GSH (Dictyostelium discoideum)
GSS:Mg2+ dimer synthesizes GSH (Caenorhabditis elegans)
GSS:Mg2+ dimer synthesizes GSH (Drosophila melanogaster)
GSS:Mg2+ dimer synthesizes GSH (Danio rerio)
GSS:Mg2+ dimer synthesizes GSH (Sus scrofa)
GSS:Mg2+ dimer synthesizes GSH (Bos taurus)
GSS:Mg2+ dimer synthesizes GSH (Canis familiaris)
GSS:Mg2+ dimer synthesizes GSH (Rattus norvegicus)
GSS:Mg2+ dimer synthesizes GSH (Mus musculus)
GSS:Mg2+ dimer synthesizes GSH (Homo sapiens)
GSSebGalNac is reduced and methylated to MeSebGalNac (Rattus norvegicus)
GSSeSG is reduced to GSSeH and GSH by Gsr (Rattus norvegicus)
GSSeSG is reduced to GSSeH and GSH by GSR (Homo sapiens)
GSSebGalNac is reduced and methylated to MeSebGalNac (Homo sapiens)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Homo sapiens)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Rattus norvegicus)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Canis familiaris)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Bos taurus)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Xenopus tropicalis)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Gallus gallus)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Caenorhabditis elegans)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Dictyostelium discoideum)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Saccharomyces cerevisiae)
glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)
This entity regulates
Negatively
GSS:Mg2+ dimer synthesizes GSH
(Plasmodium falciparum)
GSS:Mg2+ dimer synthesizes GSH
(Gallus gallus)
GSS:Mg2+ dimer synthesizes GSH
(Saccharomyces cerevisiae)
GSS:Mg2+ dimer synthesizes GSH
(Schizosaccharomyces pombe)
GSS:Mg2+ dimer synthesizes GSH
(Dictyostelium discoideum)
GSS:Mg2+ dimer synthesizes GSH
(Caenorhabditis elegans)
GSS:Mg2+ dimer synthesizes GSH
(Drosophila melanogaster)
GSS:Mg2+ dimer synthesizes GSH
(Danio rerio)
GSS:Mg2+ dimer synthesizes GSH
(Sus scrofa)
GSS:Mg2+ dimer synthesizes GSH
(Bos taurus)
GSS:Mg2+ dimer synthesizes GSH
(Canis familiaris)
GSS:Mg2+ dimer synthesizes GSH
(Rattus norvegicus)
GSS:Mg2+ dimer synthesizes GSH
(Mus musculus)
GSS:Mg2+ dimer synthesizes GSH
(Homo sapiens)
Other forms of this molecule
GSH [extracellular region]
Cross References
COMPOUND
C00051
ZINC
000003830891
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