Reactome | 2OG [cytosol]

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2OG [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-880053] 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] - Homo sapiens [Reaction:R-PFA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Plasmodium falciparum [Reaction:R-DDI-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Dictyostelium discoideum [Reaction:R-CEL-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Caenorhabditis elegans [Reaction:R-DME-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Drosophila melanogaster [Reaction:R-GGA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Gallus gallus [Reaction:R-XTR-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Xenopus tropicalis [Reaction:R-DRE-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Danio rerio [Reaction:R-BTA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Bos taurus [Reaction:R-CFA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Canis familiaris [Reaction:R-RNO-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Rattus norvegicus [Reaction:R-MMU-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Mus musculus [Reaction:R-HSA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 - Homo sapiens [Reaction:R-DDI-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Dictyostelium discoideum [Reaction:R-DME-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Drosophila melanogaster [Reaction:R-GGA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Gallus gallus [Reaction:R-XTR-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Xenopus tropicalis [Reaction:R-DRE-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Danio rerio [Reaction:R-SSC-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Sus scrofa [Reaction:R-BTA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Bos taurus [Reaction:R-CFA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Canis familiaris [Reaction:R-MMU-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Mus musculus [Reaction:R-HSA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 - Homo sapiens [Reaction:R-SPO-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Schizosaccharomyces pombe [Reaction:R-CEL-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Caenorhabditis elegans [Reaction:R-DME-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Drosophila melanogaster [Reaction:R-GGA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Gallus gallus [Reaction:R-XTR-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Xenopus tropicalis [Reaction:R-DRE-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Danio rerio [Reaction:R-SSC-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Sus scrofa [Reaction:R-BTA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Bos taurus [Reaction:R-CFA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Canis familiaris [Reaction:R-RNO-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Rattus norvegicus [Reaction:R-MMU-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Mus musculus [Reaction:R-HSA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Homo sapiens [Reaction:R-DDI-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Dictyostelium discoideum [Reaction:R-DME-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Drosophila melanogaster [Reaction:R-GGA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Gallus gallus [Reaction:R-XTR-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Xenopus tropicalis [Reaction:R-DRE-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Danio rerio [Reaction:R-SSC-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Sus scrofa [Reaction:R-BTA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Bos taurus [Reaction:R-CFA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Canis familiaris [Reaction:R-RNO-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Rattus norvegicus [Reaction:R-MMU-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Mus musculus [Reaction:R-HSA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 - Homo sapiens [Reaction:R-CEL-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Caenorhabditis elegans [Reaction:R-DME-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Drosophila melanogaster [Reaction:R-XTR-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Xenopus tropicalis [Reaction:R-SSC-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Sus scrofa [Reaction:R-BTA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Bos taurus [Reaction:R-CFA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Canis familiaris [Reaction:R-RNO-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Rattus norvegicus [Reaction:R-MMU-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Mus musculus [Reaction:R-HSA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Homo sapiens [Reaction:R-GGA-372719] aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate - Gallus gallus [Reaction:R-CEL-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Caenorhabditis elegans [Reaction:R-DME-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Drosophila melanogaster [Reaction:R-GGA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Gallus gallus [Reaction:R-XTR-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Xenopus tropicalis [Reaction:R-DRE-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Danio rerio [Reaction:R-SSC-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Sus scrofa [Reaction:R-BTA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Bos taurus [Reaction:R-CFA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Canis familiaris [Reaction:R-RNO-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Rattus norvegicus [Reaction:R-MMU-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Mus musculus [Reaction:R-HSA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates - Homo sapiens [Reaction:R-CEL-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Caenorhabditis elegans [Reaction:R-DME-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Drosophila melanogaster [Reaction:R-GGA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Gallus gallus [Reaction:R-XTR-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Xenopus tropicalis [Reaction:R-DRE-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Danio rerio [Reaction:R-SSC-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Sus scrofa [Reaction:R-BTA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Bos taurus [Reaction:R-CFA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Canis familiaris [Reaction:R-RNO-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Rattus norvegicus [Reaction:R-MMU-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Mus musculus [Reaction:R-HSA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids - Homo sapiens [Reaction:R-HSA-901097] PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA - Homo sapiens [Reaction:R-SCE-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Saccharomyces cerevisiae [Reaction:R-SPO-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Schizosaccharomyces pombe [Reaction:R-DDI-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Dictyostelium discoideum [Reaction:R-CEL-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Caenorhabditis elegans [Reaction:R-DME-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Drosophila melanogaster [Reaction:R-GGA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Gallus gallus [Reaction:R-XTR-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Xenopus tropicalis [Reaction:R-DRE-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Danio rerio [Reaction:R-SSC-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Sus scrofa [Reaction:R-BTA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Bos taurus [Reaction:R-CFA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Canis familiaris [Reaction:R-MMU-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Mus musculus [Reaction:R-HSA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Homo sapiens [Reaction:R-RNO-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA - Rattus norvegicus [Reaction:R-SCE-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Saccharomyces cerevisiae [Reaction:R-CEL-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Caenorhabditis elegans [Reaction:R-DME-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Drosophila melanogaster [Reaction:R-GGA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Gallus gallus [Reaction:R-XTR-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Xenopus tropicalis [Reaction:R-DRE-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Danio rerio [Reaction:R-SSC-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Sus scrofa [Reaction:R-BTA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Bos taurus [Reaction:R-CFA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Canis familiaris [Reaction:R-RNO-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Rattus norvegicus [Reaction:R-MMU-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Mus musculus [Reaction:R-HSA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA - Homo sapiens [Reaction:R-DDI-71155] TAT deaminates tyrosine - Dictyostelium discoideum [Reaction:R-CEL-71155] TAT deaminates tyrosine - Caenorhabditis elegans [Reaction:R-DME-71155] TAT deaminates tyrosine - Drosophila melanogaster [Reaction:R-XTR-71155] TAT deaminates tyrosine - Xenopus tropicalis [Reaction:R-DRE-71155] TAT deaminates tyrosine - Danio rerio [Reaction:R-SSC-71155] TAT deaminates tyrosine - Sus scrofa [Reaction:R-BTA-71155] TAT deaminates tyrosine - Bos taurus [Reaction:R-CFA-71155] TAT deaminates tyrosine - Canis familiaris [Reaction:R-MMU-71155] TAT deaminates tyrosine - Mus musculus [Reaction:R-HSA-71155] TAT deaminates tyrosine - Homo sapiens [Reaction:R-RNO-71155] TAT deaminates tyrosine - Rattus norvegicus [Reaction:R-SPO-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Schizosaccharomyces pombe [Reaction:R-HSA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Homo sapiens [Reaction:R-SCE-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Saccharomyces cerevisiae [Reaction:R-PFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Plasmodium falciparum [Reaction:R-CEL-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Caenorhabditis elegans [Reaction:R-DME-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Drosophila melanogaster [Reaction:R-XTR-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Xenopus tropicalis [Reaction:R-DRE-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Danio rerio [Reaction:R-SSC-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Sus scrofa [Reaction:R-BTA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Bos taurus [Reaction:R-CFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Canis familiaris [Reaction:R-RNO-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Rattus norvegicus [Reaction:R-MMU-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Mus musculus [Reaction:R-SCE-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Saccharomyces cerevisiae [Reaction:R-SPO-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Schizosaccharomyces pombe [Reaction:R-DDI-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Dictyostelium discoideum [Reaction:R-CEL-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Caenorhabditis elegans [Reaction:R-DME-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Drosophila melanogaster [Reaction:R-XTR-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Xenopus tropicalis [Reaction:R-DRE-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Danio rerio [Reaction:R-SSC-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Sus scrofa [Reaction:R-BTA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Bos taurus [Reaction:R-CFA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Canis familiaris [Reaction:R-RNO-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Rattus norvegicus [Reaction:R-MMU-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Mus musculus [Reaction:R-HSA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR - Homo sapiens [Reaction:R-GGA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Gallus gallus [Reaction:R-CEL-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Caenorhabditis elegans [Reaction:R-DME-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Drosophila melanogaster [Reaction:R-DRE-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Danio rerio [Reaction:R-XTR-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Xenopus tropicalis [Reaction:R-SSC-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Sus scrofa [Reaction:R-BTA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Bos taurus [Reaction:R-CFA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Canis familiaris [Reaction:R-RNO-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Rattus norvegicus [Reaction:R-MMU-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Mus musculus [Reaction:R-SCE-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Saccharomyces cerevisiae [Reaction:R-SPO-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Schizosaccharomyces pombe [Reaction:R-DDI-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Dictyostelium discoideum [Reaction:R-CEL-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Caenorhabditis elegans [Reaction:R-DME-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Drosophila melanogaster [Reaction:R-GGA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Gallus gallus [Reaction:R-XTR-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Xenopus tropicalis [Reaction:R-DRE-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Danio rerio [Reaction:R-SSC-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Sus scrofa [Reaction:R-BTA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Bos taurus [Reaction:R-CFA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Canis familiaris [Reaction:R-RNO-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Rattus norvegicus [Reaction:R-MMU-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Mus musculus [Reaction:R-HSA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Homo sapiens [Reaction:R-MMU-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Mus musculus [Reaction:R-HSA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Homo sapiens [Reaction:R-RNO-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Rattus norvegicus [Reaction:R-CFA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Canis familiaris [Reaction:R-BTA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Bos taurus [Reaction:R-SSC-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Sus scrofa [Reaction:R-XTR-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Xenopus tropicalis [Reaction:R-GGA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Gallus gallus [Reaction:R-DME-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Drosophila melanogaster [Reaction:R-CEL-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A - Caenorhabditis elegans [Reaction:R-MMU-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Mus musculus [Reaction:R-MMU-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Mus musculus [Reaction:R-HSA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Homo sapiens [Reaction:R-HSA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Homo sapiens [Reaction:R-RNO-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Rattus norvegicus [Reaction:R-RNO-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Rattus norvegicus [Reaction:R-CFA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Canis familiaris [Reaction:R-CFA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Canis familiaris [Reaction:R-BTA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Bos taurus [Reaction:R-BTA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Bos taurus [Reaction:R-SSC-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Sus scrofa [Reaction:R-SSC-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Sus scrofa [Reaction:R-XTR-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Xenopus tropicalis [Reaction:R-XTR-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Xenopus tropicalis [Reaction:R-GGA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Gallus gallus [Reaction:R-GGA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Gallus gallus [Reaction:R-DME-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Drosophila melanogaster [Reaction:R-DME-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Drosophila melanogaster [Reaction:R-CEL-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Caenorhabditis elegans [Reaction:R-CEL-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A - Caenorhabditis elegans [Reaction:R-HSA-1234179] Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) - Homo sapiens [Reaction:R-HSA-1234179] Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) - Homo sapiens [Reaction:R-MMU-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Mus musculus [Reaction:R-HSA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Homo sapiens [Reaction:R-RNO-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Rattus norvegicus [Reaction:R-CFA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Canis familiaris [Reaction:R-BTA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Bos taurus [Reaction:R-SSC-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Sus scrofa [Reaction:R-DRE-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Danio rerio [Reaction:R-XTR-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Xenopus tropicalis [Reaction:R-GGA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) - Gallus gallus [Reaction:R-HSA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane - Homo sapiens
crossReference	[DatabaseIdentifier:29407] COMPOUND:C00026
dbId	29406
deleted	[Deleted:9629526] Deletion of instance: 1130662
displayName	2OG [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9629524] D'Eustachio, Peter, 2018-11-21
name	2OG 2-oxoglutarate 2-oxoglutaric acid Oxoglutaric acid 2-Ketoglutaric acid alpha-Ketoglutaric acid 2-Oxoglutarate alpha-ketoglutarate
producedByEvent	[Reaction:R-GGA-372742] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Gallus gallus [Reaction:R-SCE-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Saccharomyces cerevisiae [Reaction:R-SPO-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Schizosaccharomyces pombe [Reaction:R-DDI-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Dictyostelium discoideum [Reaction:R-CEL-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Caenorhabditis elegans [Reaction:R-DME-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Drosophila melanogaster [Reaction:R-GGA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Gallus gallus [Reaction:R-XTR-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Xenopus tropicalis [Reaction:R-DRE-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Danio rerio [Reaction:R-SSC-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Sus scrofa [Reaction:R-BTA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Bos taurus [Reaction:R-CFA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Canis familiaris [Reaction:R-RNO-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Rattus norvegicus [Reaction:R-MMU-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Mus musculus [Reaction:R-HSA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ - Homo sapiens [Reaction:R-HSA-390347] Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane - Homo sapiens [Reaction:R-SCE-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Saccharomyces cerevisiae [Reaction:R-SPO-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Schizosaccharomyces pombe [Reaction:R-DDI-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Dictyostelium discoideum [Reaction:R-CEL-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Caenorhabditis elegans [Reaction:R-DME-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Drosophila melanogaster [Reaction:R-GGA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Gallus gallus [Reaction:R-XTR-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Xenopus tropicalis [Reaction:R-SSC-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Sus scrofa [Reaction:R-BTA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Bos taurus [Reaction:R-CFA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Canis familiaris [Reaction:R-RNO-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Rattus norvegicus [Reaction:R-MMU-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Mus musculus [Reaction:R-HSA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Homo sapiens [Reaction:R-DRE-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Danio rerio [Reaction:R-DDI-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Dictyostelium discoideum [Reaction:R-CFA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Canis familiaris [Reaction:R-GGA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Gallus gallus [Reaction:R-CEL-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Caenorhabditis elegans [Reaction:R-DME-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Drosophila melanogaster [Reaction:R-DRE-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Danio rerio [Reaction:R-XTR-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Xenopus tropicalis [Reaction:R-SSC-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Sus scrofa [Reaction:R-BTA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Bos taurus [Reaction:R-RNO-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Rattus norvegicus [Reaction:R-MMU-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Mus musculus [Reaction:R-HSA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] - Homo sapiens [Reaction:R-HSA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Homo sapiens [Reaction:R-MMU-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Mus musculus [Reaction:R-RNO-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Rattus norvegicus [Reaction:R-CFA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Canis familiaris [Reaction:R-BTA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Bos taurus [Reaction:R-SSC-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Sus scrofa [Reaction:R-DRE-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Danio rerio [Reaction:R-XTR-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Xenopus tropicalis [Reaction:R-GGA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Gallus gallus [Reaction:R-DME-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Drosophila melanogaster [Reaction:R-CEL-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Caenorhabditis elegans [Reaction:R-SPO-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Schizosaccharomyces pombe [Reaction:R-SCE-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] - Saccharomyces cerevisiae [Reaction:R-GGA-376887] 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] - Gallus gallus [Reaction:R-GGA-372717] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) - Gallus gallus [Reaction:R-DDI-517444] TAT aminates HPP - Dictyostelium discoideum [Reaction:R-CEL-517444] TAT aminates HPP - Caenorhabditis elegans [Reaction:R-DME-517444] TAT aminates HPP - Drosophila melanogaster [Reaction:R-XTR-517444] TAT aminates HPP - Xenopus tropicalis [Reaction:R-DRE-517444] TAT aminates HPP - Danio rerio [Reaction:R-SSC-517444] TAT aminates HPP - Sus scrofa [Reaction:R-BTA-517444] TAT aminates HPP - Bos taurus [Reaction:R-CFA-517444] TAT aminates HPP - Canis familiaris [Reaction:R-RNO-517444] TAT aminates HPP - Rattus norvegicus [Reaction:R-MMU-517444] TAT aminates HPP - Mus musculus [Reaction:R-HSA-517444] TAT aminates HPP - Homo sapiens [Reaction:R-HSA-376851] SLC25A11 exchanges 2-OG and MAL - Homo sapiens [Reaction:R-CFA-376851] SLC25A11 exchanges 2-OG and MAL - Canis familiaris [Reaction:R-SCE-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Saccharomyces cerevisiae [Reaction:R-SPO-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Schizosaccharomyces pombe [Reaction:R-DDI-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Dictyostelium discoideum [Reaction:R-CEL-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Caenorhabditis elegans [Reaction:R-DME-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Drosophila melanogaster [Reaction:R-XTR-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Xenopus tropicalis [Reaction:R-DRE-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Danio rerio [Reaction:R-SSC-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Sus scrofa [Reaction:R-BTA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Bos taurus [Reaction:R-CFA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Canis familiaris [Reaction:R-RNO-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Rattus norvegicus [Reaction:R-MMU-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Mus musculus [Reaction:R-HSA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Homo sapiens [Reaction:R-DME-376851] SLC25A11 exchanges 2-OG and MAL - Drosophila melanogaster [Reaction:R-PFA-376851] SLC25A11 exchanges 2-OG and MAL - Plasmodium falciparum [Reaction:R-CEL-376851] SLC25A11 exchanges 2-OG and MAL - Caenorhabditis elegans [Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL - Danio rerio [Reaction:R-XTR-376851] SLC25A11 exchanges 2-OG and MAL - Xenopus tropicalis [Reaction:R-SSC-376851] SLC25A11 exchanges 2-OG and MAL - Sus scrofa [Reaction:R-BTA-376851] SLC25A11 exchanges 2-OG and MAL - Bos taurus [Reaction:R-RNO-376851] SLC25A11 exchanges 2-OG and MAL - Rattus norvegicus [Reaction:R-MMU-376851] SLC25A11 exchanges 2-OG and MAL - Mus musculus [Reaction:R-SCE-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Saccharomyces cerevisiae [Reaction:R-SPO-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Schizosaccharomyces pombe [Reaction:R-DDI-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Dictyostelium discoideum [Reaction:R-CEL-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Caenorhabditis elegans [Reaction:R-DME-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Drosophila melanogaster [Reaction:R-GGA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Gallus gallus [Reaction:R-XTR-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Xenopus tropicalis [Reaction:R-DRE-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Danio rerio [Reaction:R-SSC-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Sus scrofa [Reaction:R-BTA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Bos taurus [Reaction:R-CFA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Canis familiaris [Reaction:R-RNO-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Rattus norvegicus [Reaction:R-MMU-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Mus musculus [Reaction:R-HSA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] - Homo sapiens
referenceEntity	[ReferenceMolecule:chebi:16810] 2-oxoglutarate(2-) [ChEBI:16810]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-29406
updateTrackers	[UpdateTracker:9900293] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v68:[add_removeReferenceEntity] [UpdateTracker:9869283] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v33:[modifyName] [UpdateTracker:9890705] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v52:[addName] [UpdateTracker:9870939] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v39:[addName] [UpdateTracker:9874390] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v43:[addName]

Referrals

(input)	[Reaction:R-GGA-372719] aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate [Reaction:R-HSA-880053] 2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] [Reaction:R-PFA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-DDI-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-CEL-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-DME-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-GGA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-XTR-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-DRE-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-BTA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-CFA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-RNO-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-MMU-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-HSA-9629869] KDM8:Fe2+ hydroxylates an arginine residue of RPS6 [Reaction:R-DDI-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-DME-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-GGA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-XTR-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-DRE-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-SSC-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-BTA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-CFA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-MMU-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-HSA-9629578] JMJD7 dimer hydroxlates a lysine residue of DRG2 [Reaction:R-SPO-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-CEL-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-DME-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-GGA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-XTR-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-DRE-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-SSC-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-BTA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-CFA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-RNO-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-MMU-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-HSA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 [Reaction:R-DDI-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-DME-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-GGA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-XTR-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-DRE-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-SSC-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-BTA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-CFA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-RNO-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-MMU-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-HSA-9629591] JMJD7 dimer hydroxlates a lysine residue of DRG1 [Reaction:R-CEL-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-DME-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-XTR-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-SSC-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-BTA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-CFA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-RNO-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-MMU-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-HSA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 [Reaction:R-CEL-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-DME-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-GGA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-XTR-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-DRE-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-SSC-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-BTA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-CFA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-RNO-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-MMU-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-HSA-561059] OAT2 and OAT4 mediate transport of sulphate conjugates [Reaction:R-CEL-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-DME-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-GGA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-XTR-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-DRE-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-SSC-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-BTA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-CFA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-RNO-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-MMU-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-HSA-561041] OAT1,2,3 transport organic anions with antiport of dicarboxylic acids [Reaction:R-HSA-901097] PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA [Reaction:R-SCE-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-SPO-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-DDI-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-CEL-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-DME-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-GGA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-XTR-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-DRE-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-SSC-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-BTA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-CFA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-MMU-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-HSA-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-RNO-893596] PXLP-KYAT1 dimer transaminates L-KYN to KYNA [Reaction:R-SCE-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-CEL-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-DME-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-GGA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-XTR-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-DRE-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-SSC-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-BTA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-CFA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-RNO-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-MMU-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-HSA-71261] BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA [Reaction:R-DDI-71155] TAT deaminates tyrosine [Reaction:R-CEL-71155] TAT deaminates tyrosine [Reaction:R-DME-71155] TAT deaminates tyrosine [Reaction:R-XTR-71155] TAT deaminates tyrosine [Reaction:R-DRE-71155] TAT deaminates tyrosine [Reaction:R-SSC-71155] TAT deaminates tyrosine [Reaction:R-BTA-71155] TAT deaminates tyrosine [Reaction:R-CFA-71155] TAT deaminates tyrosine [Reaction:R-MMU-71155] TAT deaminates tyrosine [Reaction:R-HSA-71155] TAT deaminates tyrosine [Reaction:R-RNO-71155] TAT deaminates tyrosine [Reaction:R-SPO-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-HSA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-SCE-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-PFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-CEL-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-DME-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-XTR-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-DRE-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-SSC-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-BTA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-CFA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-RNO-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-MMU-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane [Reaction:R-SCE-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-SPO-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-DDI-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-CEL-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-DME-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-XTR-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-DRE-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-SSC-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-BTA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-CFA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-RNO-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-MMU-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-HSA-70523] PXLP-K314-GPT transaminates L-Ala to form PYR [Reaction:R-GGA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-CEL-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-DME-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-DRE-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-XTR-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-SSC-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-BTA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-CFA-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-RNO-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-MMU-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp [Reaction:R-SCE-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-SPO-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-DDI-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-CEL-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-DME-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-GGA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-XTR-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-DRE-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-SSC-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-BTA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-CFA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-RNO-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-MMU-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-HSA-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] [Reaction:R-MMU-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-HSA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-RNO-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-CFA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-BTA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-SSC-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-XTR-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-GGA-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-DME-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-CEL-1234173] Cytosolic PHD2,3 hydroxylates proline residues on HIF3A [Reaction:R-MMU-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-HSA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-RNO-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-CFA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-BTA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-SSC-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-XTR-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-GGA-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-DME-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-CEL-1234177] Cytosolic PHD2,3 hydroxylates proline residues on HIF1A [Reaction:R-HSA-1234179] Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) [Reaction:R-MMU-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-HSA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-RNO-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-CFA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-BTA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-SSC-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-DRE-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-XTR-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-GGA-1234164] Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) [Reaction:R-HSA-198440] SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
(output)	[Reaction:R-GGA-376887] 2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] [Reaction:R-GGA-372742] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-GGA-372717] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) [Reaction:R-SCE-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-SPO-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-DDI-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-CEL-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-DME-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-GGA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-XTR-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-DRE-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-SSC-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-BTA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-CFA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-RNO-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-MMU-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-HSA-389540] isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ [Reaction:R-DDI-517444] TAT aminates HPP [Reaction:R-CEL-517444] TAT aminates HPP [Reaction:R-DME-517444] TAT aminates HPP [Reaction:R-XTR-517444] TAT aminates HPP [Reaction:R-DRE-517444] TAT aminates HPP [Reaction:R-SSC-517444] TAT aminates HPP [Reaction:R-BTA-517444] TAT aminates HPP [Reaction:R-CFA-517444] TAT aminates HPP [Reaction:R-RNO-517444] TAT aminates HPP [Reaction:R-MMU-517444] TAT aminates HPP [Reaction:R-HSA-517444] TAT aminates HPP [Reaction:R-HSA-390347] Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane [Reaction:R-SCE-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-SPO-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-DDI-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-CEL-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-DME-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-GGA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-XTR-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-SSC-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-BTA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-CFA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-RNO-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-MMU-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-HSA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-DRE-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Reaction:R-HSA-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-DDI-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-CFA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-CFA-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-SCE-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-SPO-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-DDI-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-CEL-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-DME-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-XTR-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-DRE-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-SSC-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-BTA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-CFA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-RNO-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-MMU-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-HSA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala [Reaction:R-GGA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-DME-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-PFA-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-CEL-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-CEL-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-DME-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-DRE-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-DRE-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-XTR-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-XTR-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-SSC-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-SSC-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-BTA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-BTA-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-RNO-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-RNO-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-MMU-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-MMU-376851] SLC25A11 exchanges 2-OG and MAL [Reaction:R-SCE-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-SPO-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-DDI-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-CEL-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-DME-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-GGA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-XTR-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-DRE-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-SSC-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-BTA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-CFA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-RNO-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-MMU-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] [Reaction:R-HSA-372480] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Reaction:R-HSA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-MMU-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-RNO-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-CFA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-BTA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-SSC-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-DRE-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-XTR-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-GGA-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-DME-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-CEL-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-SPO-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-SCE-70581] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] [Reaction:R-HSA-508189] a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1]
(replacementInstances)	[Deleted:9629526] Deletion of instance: 1130662
(updatedInstance)	[UpdateTracker:9900293] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v68:[add_removeReferenceEntity] [UpdateTracker:9869283] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v33:[modifyName] [UpdateTracker:9890705] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v52:[addName] [UpdateTracker:9870939] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v39:[addName] [UpdateTracker:9874390] Update Tracker - [SimpleEntity:29406] 2OG [cytosol] - v43:[addName]

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