Reactome | KDM8:Fe2+ hydroxylates an arginine residue of RCCD1

Schema > Reaction > Entries

KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 Show undefined attributes

catalystActivity	[CatalystActivity:10318880] peptidyl-arginine 3-dioxygenase activity of KDM8:Fe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10318891
displayName	KDM8:Fe2+ hydroxylates an arginine residue of RCCD1
eventOf	[Pathway:R-CFA-9629569] Protein hydroxylation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160469] peptidyl-arginine hydroxylation
inferredFrom	[Reaction:R-HSA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 - Homo sapiens
input	[SimpleEntity:R-ALL-29406] 2OG [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol] [EntityWithAccessionedSequence:R-CFA-9629873] RCCD1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 2-oxoglutarate + L-arginyl-(protein) + O2 => (3R)-3-hydroxy-L-arginyl-(protein) + CO2 + succinate
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [EntityWithAccessionedSequence:R-CFA-9629871] RCCD1 [cytosol] [SimpleEntity:R-ALL-29434] SUCCA [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9629888
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9629569] Protein hydroxylation
(inferredTo)	[Reaction:R-HSA-9629888] KDM8:Fe2+ hydroxylates an arginine residue of RCCD1

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