SLC25A11 exchanges 2-OG and MAL

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9815400] oxoglutarate:malate antiporter activity of SLC25A11 homodimer [mitochondrial inner membrane] Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier
category transition
compartment
created [InstanceEdit:376857] D'Eustachio, P, 2008-09-09 21:21:16
crossReference
dbId 376851
displayName SLC25A11 exchanges 2-OG and MAL
edited
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
modified [InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
  • SLC25A11 exchanges 2-OG and MAL
  • SLC25A11 exchanges alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane
  • (S)-malate(out) + 2-oxoglutarate(in) => (S)-malate(in) + 2-oxoglutarate(out)
orthologousEvent
output
precedingEvent
releaseDate 2008-06-30
reviewStatus [ReviewStatus:9821382] five stars
reviewed
revised
schemaClass Reaction
species
stId R-HSA-376851
summation
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