Reactome | JMJD4:Fe2+ hydroxylates a lysine residue of ETF1

Schema > Reaction > Entries

JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 Show undefined attributes

catalystActivity	[CatalystActivity:10816507] peptidyl-lysine 4-dioxygenase activity of JMJD4:Fe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10816509
displayName	JMJD4:Fe2+ hydroxylates a lysine residue of ETF1
eventOf	[Pathway:R-GGA-9629569] Protein hydroxylation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:5982] peptidyl-lysine hydroxylation
inferredFrom	[Reaction:R-HSA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 - Homo sapiens
input	[SimpleEntity:R-ALL-29406] 2OG [cytosol] [EntityWithAccessionedSequence:R-GGA-54433] ETF1 [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 2-oxoglutarate + L-lysyl-(protein) + O2 => 4-hydroxy-L-lysyl-(protein) + CO2 + succinate
output	[SimpleEntity:R-ALL-113528] CO2 [cytosol] [EntityWithAccessionedSequence:R-GGA-9629948] ETF1 [cytosol] [SimpleEntity:R-ALL-29434] SUCCA [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9629946
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9629569] Protein hydroxylation
(inferredTo)	[Reaction:R-HSA-9629946] JMJD4:Fe2+ hydroxylates a lysine residue of ETF1

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