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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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Analyse gene list
Analyse gene expression
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2OG [cytosol]
Stable Identifier
R-ALL-29406
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
2-oxoglutarate, 2-oxoglutaric acid, Oxoglutaric acid, 2-Ketoglutaric acid, alpha-Ketoglutaric acid, 2-Oxoglutarate, alpha-ketoglutarate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to hypoxia (Bos taurus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Bos taurus)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Bos taurus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Bos taurus)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Bos taurus)
2OG [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
2OG [cytosol]
Respiratory electron transport (Bos taurus)
Malate-aspartate shuttle (Bos taurus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Bos taurus)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Bos taurus)
2OG [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Alanine metabolism (Bos taurus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Bos taurus)
2OG [cytosol]
Aspartate and asparagine metabolism (Bos taurus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Bos taurus)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Bos taurus)
2OG [cytosol]
Branched-chain amino acid catabolism (Bos taurus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Bos taurus)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Bos taurus)
2OG [cytosol]
Carnitine synthesis (Bos taurus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)
2OG [cytosol]
Lysine catabolism (Bos taurus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Bos taurus)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Bos taurus)
Tyrosine catabolism (Bos taurus)
TAT aminates HPP (Bos taurus)
2OG [cytosol]
TAT deaminates tyrosine (Bos taurus)
2OG [cytosol]
Serine metabolism (Bos taurus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Bos taurus)
2OG [cytosol]
Tryptophan catabolism (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Bos taurus)
2OG [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
NADPH regeneration (Bos taurus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Bos taurus)
2OG [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)
Protein hydroxylation (Bos taurus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Bos taurus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Bos taurus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Bos taurus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Bos taurus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Bos taurus)
2OG [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
SLC-mediated transport of organic anions (Bos taurus)
Organic anion transport by SLC22 transporters (Bos taurus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Bos taurus)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Bos taurus)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Bos taurus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Bos taurus)
2OG [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to hypoxia (Caenorhabditis elegans)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Caenorhabditis elegans)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Caenorhabditis elegans)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Caenorhabditis elegans)
2OG [cytosol]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
2OG [cytosol]
Respiratory electron transport (Caenorhabditis elegans)
Malate-aspartate shuttle (Caenorhabditis elegans)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Caenorhabditis elegans)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Caenorhabditis elegans)
2OG [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Alanine metabolism (Caenorhabditis elegans)
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)
2OG [cytosol]
Aspartate and asparagine metabolism (Caenorhabditis elegans)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Caenorhabditis elegans)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Caenorhabditis elegans)
2OG [cytosol]
Branched-chain amino acid catabolism (Caenorhabditis elegans)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Caenorhabditis elegans)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Caenorhabditis elegans)
2OG [cytosol]
Carnitine synthesis (Caenorhabditis elegans)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)
2OG [cytosol]
Lysine catabolism (Caenorhabditis elegans)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Caenorhabditis elegans)
Tyrosine catabolism (Caenorhabditis elegans)
TAT aminates HPP (Caenorhabditis elegans)
2OG [cytosol]
TAT deaminates tyrosine (Caenorhabditis elegans)
2OG [cytosol]
Serine metabolism (Caenorhabditis elegans)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Caenorhabditis elegans)
2OG [cytosol]
Tryptophan catabolism (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Caenorhabditis elegans)
2OG [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
NADPH regeneration (Caenorhabditis elegans)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Caenorhabditis elegans)
2OG [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Caenorhabditis elegans)
Protein hydroxylation (Caenorhabditis elegans)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Caenorhabditis elegans)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Caenorhabditis elegans)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Caenorhabditis elegans)
2OG [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
SLC-mediated transport of organic anions (Caenorhabditis elegans)
Organic anion transport by SLC22 transporters (Caenorhabditis elegans)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Caenorhabditis elegans)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Caenorhabditis elegans)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Caenorhabditis elegans)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Caenorhabditis elegans)
2OG [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to hypoxia (Canis familiaris)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Canis familiaris)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Canis familiaris)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Canis familiaris)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Canis familiaris)
2OG [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
2OG [cytosol]
Respiratory electron transport (Canis familiaris)
Malate-aspartate shuttle (Canis familiaris)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Canis familiaris)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Canis familiaris)
2OG [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Alanine metabolism (Canis familiaris)
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)
2OG [cytosol]
Aspartate and asparagine metabolism (Canis familiaris)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Canis familiaris)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Canis familiaris)
2OG [cytosol]
Branched-chain amino acid catabolism (Canis familiaris)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Canis familiaris)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Canis familiaris)
2OG [cytosol]
Carnitine synthesis (Canis familiaris)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Canis familiaris)
2OG [cytosol]
Lysine catabolism (Canis familiaris)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Canis familiaris)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Canis familiaris)
Tyrosine catabolism (Canis familiaris)
TAT aminates HPP (Canis familiaris)
2OG [cytosol]
TAT deaminates tyrosine (Canis familiaris)
2OG [cytosol]
Serine metabolism (Canis familiaris)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Canis familiaris)
2OG [cytosol]
Tryptophan catabolism (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Canis familiaris)
2OG [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of cofactors (Canis familiaris)
NADPH regeneration (Canis familiaris)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Canis familiaris)
2OG [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
Protein hydroxylation (Canis familiaris)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Canis familiaris)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Canis familiaris)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Canis familiaris)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Canis familiaris)
2OG [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
SLC-mediated transport of organic anions (Canis familiaris)
Organic anion transport by SLC22 transporters (Canis familiaris)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Canis familiaris)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Canis familiaris)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Canis familiaris)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Canis familiaris)
2OG [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to hypoxia (Danio rerio)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Danio rerio)
2OG [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
2OG [cytosol]
Respiratory electron transport (Danio rerio)
Malate-aspartate shuttle (Danio rerio)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Danio rerio)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Danio rerio)
2OG [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Alanine metabolism (Danio rerio)
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Danio rerio)
2OG [cytosol]
Aspartate and asparagine metabolism (Danio rerio)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Danio rerio)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Danio rerio)
2OG [cytosol]
Branched-chain amino acid catabolism (Danio rerio)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Danio rerio)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)
2OG [cytosol]
Carnitine synthesis (Danio rerio)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)
2OG [cytosol]
Lysine catabolism (Danio rerio)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Danio rerio)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Danio rerio)
Tyrosine catabolism (Danio rerio)
TAT aminates HPP (Danio rerio)
2OG [cytosol]
TAT deaminates tyrosine (Danio rerio)
2OG [cytosol]
Serine metabolism (Danio rerio)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Danio rerio)
2OG [cytosol]
Tryptophan catabolism (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Danio rerio)
2OG [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of cofactors (Danio rerio)
NADPH regeneration (Danio rerio)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Danio rerio)
2OG [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Danio rerio)
Protein hydroxylation (Danio rerio)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Danio rerio)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Danio rerio)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Danio rerio)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Danio rerio)
2OG [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
SLC-mediated transport of organic anions (Danio rerio)
Organic anion transport by SLC22 transporters (Danio rerio)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Danio rerio)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Danio rerio)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Danio rerio)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Danio rerio)
2OG [cytosol]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism (Dictyostelium discoideum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
2OG [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Alanine metabolism (Dictyostelium discoideum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Dictyostelium discoideum)
2OG [cytosol]
Branched-chain amino acid catabolism (Dictyostelium discoideum)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Dictyostelium discoideum)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Dictyostelium discoideum)
2OG [cytosol]
Lysine catabolism (Dictyostelium discoideum)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Dictyostelium discoideum)
Tyrosine catabolism (Dictyostelium discoideum)
TAT aminates HPP (Dictyostelium discoideum)
2OG [cytosol]
TAT deaminates tyrosine (Dictyostelium discoideum)
2OG [cytosol]
Serine metabolism (Dictyostelium discoideum)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Dictyostelium discoideum)
2OG [cytosol]
Tryptophan catabolism (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Dictyostelium discoideum)
2OG [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of cofactors (Dictyostelium discoideum)
NADPH regeneration (Dictyostelium discoideum)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Dictyostelium discoideum)
2OG [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Dictyostelium discoideum)
Protein hydroxylation (Dictyostelium discoideum)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Dictyostelium discoideum)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Dictyostelium discoideum)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Dictyostelium discoideum)
2OG [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to hypoxia (Drosophila melanogaster)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Drosophila melanogaster)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Drosophila melanogaster)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Drosophila melanogaster)
2OG [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
2OG [cytosol]
Respiratory electron transport (Drosophila melanogaster)
Malate-aspartate shuttle (Drosophila melanogaster)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Drosophila melanogaster)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Drosophila melanogaster)
2OG [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Alanine metabolism (Drosophila melanogaster)
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Drosophila melanogaster)
2OG [cytosol]
Aspartate and asparagine metabolism (Drosophila melanogaster)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Drosophila melanogaster)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Drosophila melanogaster)
2OG [cytosol]
Branched-chain amino acid catabolism (Drosophila melanogaster)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Drosophila melanogaster)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Drosophila melanogaster)
2OG [cytosol]
Carnitine synthesis (Drosophila melanogaster)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)
2OG [cytosol]
Lysine catabolism (Drosophila melanogaster)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Drosophila melanogaster)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Drosophila melanogaster)
Tyrosine catabolism (Drosophila melanogaster)
TAT aminates HPP (Drosophila melanogaster)
2OG [cytosol]
TAT deaminates tyrosine (Drosophila melanogaster)
2OG [cytosol]
Serine metabolism (Drosophila melanogaster)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Drosophila melanogaster)
2OG [cytosol]
Tryptophan catabolism (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Drosophila melanogaster)
2OG [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
NADPH regeneration (Drosophila melanogaster)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Drosophila melanogaster)
2OG [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Drosophila melanogaster)
Protein hydroxylation (Drosophila melanogaster)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Drosophila melanogaster)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Drosophila melanogaster)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Drosophila melanogaster)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Drosophila melanogaster)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Drosophila melanogaster)
2OG [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
SLC-mediated transport of organic anions (Drosophila melanogaster)
Organic anion transport by SLC22 transporters (Drosophila melanogaster)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Drosophila melanogaster)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Drosophila melanogaster)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Drosophila melanogaster)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Drosophila melanogaster)
2OG [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to hypoxia (Gallus gallus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Gallus gallus)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Gallus gallus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Gallus gallus)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Gallus gallus)
2OG [cytosol]
Metabolism (Gallus gallus)
Amino acid metabolism (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
2OG [cytosol]
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
2OG [cytosol]
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] (Gallus gallus)
2OG [cytosol]
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
2OG [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)
Protein hydroxylation (Gallus gallus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Gallus gallus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Gallus gallus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Gallus gallus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Gallus gallus)
2OG [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
SLC-mediated transport of organic anions (Gallus gallus)
Organic anion transport by SLC22 transporters (Gallus gallus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Gallus gallus)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Gallus gallus)
2OG [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to hypoxia (Homo sapiens)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Homo sapiens)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Homo sapiens)
Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Homo sapiens)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Homo sapiens)
2OG [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate (Homo sapiens)
2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] (Homo sapiens)
2OG [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
2OG [cytosol]
Respiratory electron transport (Homo sapiens)
Malate-aspartate shuttle (Homo sapiens)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Homo sapiens)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Homo sapiens)
2OG [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Alanine metabolism (Homo sapiens)
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Homo sapiens)
2OG [cytosol]
Aspartate and asparagine metabolism (Homo sapiens)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Homo sapiens)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Homo sapiens)
2OG [cytosol]
Branched-chain amino acid catabolism (Homo sapiens)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Homo sapiens)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Homo sapiens)
2OG [cytosol]
Carnitine synthesis (Homo sapiens)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Homo sapiens)
2OG [cytosol]
Lysine catabolism (Homo sapiens)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Homo sapiens)
Tyrosine catabolism (Homo sapiens)
TAT aminates HPP (Homo sapiens)
2OG [cytosol]
TAT deaminates tyrosine (Homo sapiens)
2OG [cytosol]
Serine metabolism (Homo sapiens)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Homo sapiens)
2OG [cytosol]
Tryptophan catabolism (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Homo sapiens)
2OG [cytosol]
PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA (Homo sapiens)
2OG [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
NADPH regeneration (Homo sapiens)
Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane (Homo sapiens)
2OG [cytosol]
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Homo sapiens)
2OG [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Protein hydroxylation (Homo sapiens)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Homo sapiens)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Homo sapiens)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Homo sapiens)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Homo sapiens)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Homo sapiens)
2OG [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
SLC-mediated transport of organic anions (Homo sapiens)
Organic anion transport by SLC22 transporters (Homo sapiens)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Homo sapiens)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Homo sapiens)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Homo sapiens)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Homo sapiens)
2OG [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to hypoxia (Mus musculus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Mus musculus)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Mus musculus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Mus musculus)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Mus musculus)
2OG [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
2OG [cytosol]
Respiratory electron transport (Mus musculus)
Malate-aspartate shuttle (Mus musculus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Mus musculus)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Mus musculus)
2OG [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Alanine metabolism (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)
2OG [cytosol]
Aspartate and asparagine metabolism (Mus musculus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Mus musculus)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Mus musculus)
2OG [cytosol]
Branched-chain amino acid catabolism (Mus musculus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Mus musculus)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Mus musculus)
2OG [cytosol]
Carnitine synthesis (Mus musculus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Mus musculus)
2OG [cytosol]
Lysine catabolism (Mus musculus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Mus musculus)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Mus musculus)
Tyrosine catabolism (Mus musculus)
TAT aminates HPP (Mus musculus)
2OG [cytosol]
TAT deaminates tyrosine (Mus musculus)
2OG [cytosol]
Serine metabolism (Mus musculus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Mus musculus)
2OG [cytosol]
Tryptophan catabolism (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Mus musculus)
2OG [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
NADPH regeneration (Mus musculus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Mus musculus)
2OG [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
Protein hydroxylation (Mus musculus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Mus musculus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Mus musculus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Mus musculus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Mus musculus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Mus musculus)
2OG [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
SLC-mediated transport of organic anions (Mus musculus)
Organic anion transport by SLC22 transporters (Mus musculus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Mus musculus)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Mus musculus)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Mus musculus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Mus musculus)
2OG [cytosol]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Respiratory electron transport (Plasmodium falciparum)
Malate-aspartate shuttle (Plasmodium falciparum)
SLC25A11 exchanges 2-OG and MAL (Plasmodium falciparum)
2OG [cytosol]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Plasmodium falciparum)
Protein hydroxylation (Plasmodium falciparum)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Plasmodium falciparum)
2OG [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
SLC-mediated transport of organic anions (Plasmodium falciparum)
Organic anion transport by SLC5/17/25 transporters (Plasmodium falciparum)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Plasmodium falciparum)
2OG [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to hypoxia (Rattus norvegicus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Rattus norvegicus)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Rattus norvegicus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Rattus norvegicus)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Rattus norvegicus)
2OG [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
2OG [cytosol]
Respiratory electron transport (Rattus norvegicus)
Malate-aspartate shuttle (Rattus norvegicus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Rattus norvegicus)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Rattus norvegicus)
2OG [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Alanine metabolism (Rattus norvegicus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Rattus norvegicus)
2OG [cytosol]
Aspartate and asparagine metabolism (Rattus norvegicus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Rattus norvegicus)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Rattus norvegicus)
2OG [cytosol]
Branched-chain amino acid catabolism (Rattus norvegicus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Rattus norvegicus)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Rattus norvegicus)
2OG [cytosol]
Carnitine synthesis (Rattus norvegicus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Rattus norvegicus)
2OG [cytosol]
Lysine catabolism (Rattus norvegicus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Rattus norvegicus)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Rattus norvegicus)
Tyrosine catabolism (Rattus norvegicus)
TAT aminates HPP (Rattus norvegicus)
2OG [cytosol]
TAT deaminates tyrosine (Rattus norvegicus)
2OG [cytosol]
Serine metabolism (Rattus norvegicus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Rattus norvegicus)
2OG [cytosol]
Tryptophan catabolism (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Rattus norvegicus)
2OG [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
NADPH regeneration (Rattus norvegicus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Rattus norvegicus)
2OG [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
Protein hydroxylation (Rattus norvegicus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Rattus norvegicus)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Rattus norvegicus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Rattus norvegicus)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Rattus norvegicus)
2OG [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
SLC-mediated transport of organic anions (Rattus norvegicus)
Organic anion transport by SLC22 transporters (Rattus norvegicus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Rattus norvegicus)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Rattus norvegicus)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Rattus norvegicus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Rattus norvegicus)
2OG [cytosol]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
2OG [cytosol]
Respiratory electron transport (Saccharomyces cerevisiae)
Malate-aspartate shuttle (Saccharomyces cerevisiae)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Saccharomyces cerevisiae)
2OG [cytosol]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Alanine metabolism (Saccharomyces cerevisiae)
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
2OG [cytosol]
Aspartate and asparagine metabolism (Saccharomyces cerevisiae)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Saccharomyces cerevisiae)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Saccharomyces cerevisiae)
2OG [cytosol]
Branched-chain amino acid catabolism (Saccharomyces cerevisiae)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Saccharomyces cerevisiae)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Saccharomyces cerevisiae)
2OG [cytosol]
Carnitine synthesis (Saccharomyces cerevisiae)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)
2OG [cytosol]
Serine metabolism (Saccharomyces cerevisiae)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Saccharomyces cerevisiae)
2OG [cytosol]
Tryptophan catabolism (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Saccharomyces cerevisiae)
2OG [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
NADPH regeneration (Saccharomyces cerevisiae)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Saccharomyces cerevisiae)
2OG [cytosol]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
PXLP-K314-GPT transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
2OG [cytosol]
Respiratory electron transport (Schizosaccharomyces pombe)
Malate-aspartate shuttle (Schizosaccharomyces pombe)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Schizosaccharomyces pombe)
2OG [cytosol]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Alanine metabolism (Schizosaccharomyces pombe)
PXLP-K314-GPT transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
2OG [cytosol]
Aspartate and asparagine metabolism (Schizosaccharomyces pombe)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Schizosaccharomyces pombe)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Schizosaccharomyces pombe)
2OG [cytosol]
Branched-chain amino acid catabolism (Schizosaccharomyces pombe)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Schizosaccharomyces pombe)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Schizosaccharomyces pombe)
2OG [cytosol]
Serine metabolism (Schizosaccharomyces pombe)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Schizosaccharomyces pombe)
2OG [cytosol]
Tryptophan catabolism (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Schizosaccharomyces pombe)
2OG [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of cofactors (Schizosaccharomyces pombe)
NADPH regeneration (Schizosaccharomyces pombe)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)
2OG [cytosol]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Schizosaccharomyces pombe)
Protein hydroxylation (Schizosaccharomyces pombe)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Schizosaccharomyces pombe)
2OG [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to hypoxia (Sus scrofa)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Sus scrofa)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Sus scrofa)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Sus scrofa)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Sus scrofa)
2OG [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
2OG [cytosol]
Respiratory electron transport (Sus scrofa)
Malate-aspartate shuttle (Sus scrofa)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Sus scrofa)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Sus scrofa)
2OG [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Alanine metabolism (Sus scrofa)
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Sus scrofa)
2OG [cytosol]
Aspartate and asparagine metabolism (Sus scrofa)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Sus scrofa)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Sus scrofa)
2OG [cytosol]
Branched-chain amino acid catabolism (Sus scrofa)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Sus scrofa)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Sus scrofa)
2OG [cytosol]
Carnitine synthesis (Sus scrofa)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Sus scrofa)
2OG [cytosol]
Lysine catabolism (Sus scrofa)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Sus scrofa)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Sus scrofa)
Tyrosine catabolism (Sus scrofa)
TAT aminates HPP (Sus scrofa)
2OG [cytosol]
TAT deaminates tyrosine (Sus scrofa)
2OG [cytosol]
Serine metabolism (Sus scrofa)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Sus scrofa)
2OG [cytosol]
Tryptophan catabolism (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Sus scrofa)
2OG [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
NADPH regeneration (Sus scrofa)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Sus scrofa)
2OG [cytosol]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Sus scrofa)
Protein hydroxylation (Sus scrofa)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Sus scrofa)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Sus scrofa)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Sus scrofa)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Sus scrofa)
2OG [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
SLC-mediated transport of organic anions (Sus scrofa)
Organic anion transport by SLC22 transporters (Sus scrofa)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Sus scrofa)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Sus scrofa)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Sus scrofa)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)
2OG [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to hypoxia (Xenopus tropicalis)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Xenopus tropicalis)
2OG [cytosol]
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Xenopus tropicalis)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Xenopus tropicalis)
2OG [cytosol]
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Xenopus tropicalis)
2OG [cytosol]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
2OG [cytosol]
Respiratory electron transport (Xenopus tropicalis)
Malate-aspartate shuttle (Xenopus tropicalis)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Xenopus tropicalis)
2OG [cytosol]
SLC25A11 exchanges 2-OG and MAL (Xenopus tropicalis)
2OG [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Alanine metabolism (Xenopus tropicalis)
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
2OG [cytosol]
PXLP-K314-GPT transaminates PYR to form L-Ala (Xenopus tropicalis)
2OG [cytosol]
Aspartate and asparagine metabolism (Xenopus tropicalis)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Xenopus tropicalis)
2OG [cytosol]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Xenopus tropicalis)
2OG [cytosol]
Branched-chain amino acid catabolism (Xenopus tropicalis)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Xenopus tropicalis)
2OG [cytosol]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Xenopus tropicalis)
2OG [cytosol]
Carnitine synthesis (Xenopus tropicalis)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Xenopus tropicalis)
2OG [cytosol]
Lysine catabolism (Xenopus tropicalis)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Xenopus tropicalis)
2OG [cytosol]
Phenylalanine and tyrosine metabolism (Xenopus tropicalis)
Tyrosine catabolism (Xenopus tropicalis)
TAT aminates HPP (Xenopus tropicalis)
2OG [cytosol]
TAT deaminates tyrosine (Xenopus tropicalis)
2OG [cytosol]
Serine metabolism (Xenopus tropicalis)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Xenopus tropicalis)
2OG [cytosol]
Tryptophan catabolism (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Xenopus tropicalis)
2OG [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of cofactors (Xenopus tropicalis)
NADPH regeneration (Xenopus tropicalis)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Xenopus tropicalis)
2OG [cytosol]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Xenopus tropicalis)
Protein hydroxylation (Xenopus tropicalis)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Xenopus tropicalis)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Xenopus tropicalis)
2OG [cytosol]
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Xenopus tropicalis)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Xenopus tropicalis)
2OG [cytosol]
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Xenopus tropicalis)
2OG [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
SLC-mediated transport of organic anions (Xenopus tropicalis)
Organic anion transport by SLC22 transporters (Xenopus tropicalis)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Xenopus tropicalis)
2OG [cytosol]
OAT2 and OAT4 mediate transport of sulphate conjugates (Xenopus tropicalis)
2OG [cytosol]
Organic anion transport by SLC5/17/25 transporters (Xenopus tropicalis)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Xenopus tropicalis)
2OG [cytosol]
External Reference Information
External Reference
2-oxoglutarate(2-) [ChEBI:16810]
Participates
as an input of
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
2-oxoglutarate + NADPH + H+ => (R)-2-hydroxyglutarate + NADP+ [mutant IDH1] (Homo sapiens)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Plasmodium falciparum)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Dictyostelium discoideum)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Caenorhabditis elegans)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Drosophila melanogaster)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Gallus gallus)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Xenopus tropicalis)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Danio rerio)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Bos taurus)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Canis familiaris)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Rattus norvegicus)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Mus musculus)
KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Homo sapiens)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Dictyostelium discoideum)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Drosophila melanogaster)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Gallus gallus)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Xenopus tropicalis)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Danio rerio)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Sus scrofa)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Bos taurus)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Canis familiaris)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Mus musculus)
JMJD7 dimer hydroxlates a lysine residue of DRG2 (Homo sapiens)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Schizosaccharomyces pombe)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Caenorhabditis elegans)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Drosophila melanogaster)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Gallus gallus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Xenopus tropicalis)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Danio rerio)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Sus scrofa)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Bos taurus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Canis familiaris)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Rattus norvegicus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Mus musculus)
JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Homo sapiens)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Dictyostelium discoideum)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Drosophila melanogaster)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Gallus gallus)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Xenopus tropicalis)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Danio rerio)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Sus scrofa)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Bos taurus)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Canis familiaris)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Rattus norvegicus)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Mus musculus)
JMJD7 dimer hydroxlates a lysine residue of DRG1 (Homo sapiens)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Caenorhabditis elegans)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Drosophila melanogaster)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Xenopus tropicalis)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Sus scrofa)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Bos taurus)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Rattus norvegicus)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Mus musculus)
KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Homo sapiens)
OAT2 and OAT4 mediate transport of sulphate conjugates (Caenorhabditis elegans)
OAT2 and OAT4 mediate transport of sulphate conjugates (Drosophila melanogaster)
OAT2 and OAT4 mediate transport of sulphate conjugates (Gallus gallus)
OAT2 and OAT4 mediate transport of sulphate conjugates (Xenopus tropicalis)
OAT2 and OAT4 mediate transport of sulphate conjugates (Danio rerio)
OAT2 and OAT4 mediate transport of sulphate conjugates (Sus scrofa)
OAT2 and OAT4 mediate transport of sulphate conjugates (Bos taurus)
OAT2 and OAT4 mediate transport of sulphate conjugates (Canis familiaris)
OAT2 and OAT4 mediate transport of sulphate conjugates (Rattus norvegicus)
OAT2 and OAT4 mediate transport of sulphate conjugates (Mus musculus)
OAT2 and OAT4 mediate transport of sulphate conjugates (Homo sapiens)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Caenorhabditis elegans)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Drosophila melanogaster)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Gallus gallus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Xenopus tropicalis)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Danio rerio)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Sus scrofa)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Bos taurus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Canis familiaris)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Rattus norvegicus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Mus musculus)
OAT1,2,3 transport organic anions with antiport of dicarboxylic acids (Homo sapiens)
PXLP-KYAT3 (CCBL2) dimer transaminates L-KYN to KYNA (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Gallus gallus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Rattus norvegicus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Gallus gallus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Xenopus tropicalis)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Sus scrofa)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Canis familiaris)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Rattus norvegicus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Mus musculus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Homo sapiens)
TAT deaminates tyrosine (Dictyostelium discoideum)
TAT deaminates tyrosine (Caenorhabditis elegans)
TAT deaminates tyrosine (Drosophila melanogaster)
TAT deaminates tyrosine (Xenopus tropicalis)
TAT deaminates tyrosine (Danio rerio)
TAT deaminates tyrosine (Sus scrofa)
TAT deaminates tyrosine (Bos taurus)
TAT deaminates tyrosine (Canis familiaris)
TAT deaminates tyrosine (Mus musculus)
TAT deaminates tyrosine (Homo sapiens)
TAT deaminates tyrosine (Rattus norvegicus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Schizosaccharomyces pombe)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Homo sapiens)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Saccharomyces cerevisiae)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Plasmodium falciparum)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Caenorhabditis elegans)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Drosophila melanogaster)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Xenopus tropicalis)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Danio rerio)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Bos taurus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Canis familiaris)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Rattus norvegicus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PXLP-K314-GPT transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)
PXLP-K314-GPT transaminates L-Ala to form PYR (Caenorhabditis elegans)
PXLP-K314-GPT transaminates L-Ala to form PYR (Drosophila melanogaster)
PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)
PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)
PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)
PXLP-K314-GPT transaminates L-Ala to form PYR (Bos taurus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Canis familiaris)
PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)
PXLP-K314-GPT transaminates L-Ala to form PYR (Homo sapiens)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Gallus gallus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Caenorhabditis elegans)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Drosophila melanogaster)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Danio rerio)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Xenopus tropicalis)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Sus scrofa)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Bos taurus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Canis familiaris)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Rattus norvegicus)
PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Mus musculus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Saccharomyces cerevisiae)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Schizosaccharomyces pombe)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Dictyostelium discoideum)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Caenorhabditis elegans)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Drosophila melanogaster)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Gallus gallus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Xenopus tropicalis)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Sus scrofa)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Bos taurus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Canis familiaris)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Rattus norvegicus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Mus musculus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Homo sapiens)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Mus musculus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Homo sapiens)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Rattus norvegicus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Canis familiaris)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Bos taurus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Sus scrofa)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Xenopus tropicalis)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Gallus gallus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Drosophila melanogaster)
Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Caenorhabditis elegans)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Mus musculus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Homo sapiens)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Rattus norvegicus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Canis familiaris)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Bos taurus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Sus scrofa)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Xenopus tropicalis)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Gallus gallus)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Drosophila melanogaster)
Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Caenorhabditis elegans)
Cytosolic PHD2,3 hydroxylates proline residues on EPAS1 (HIF2A) (Homo sapiens)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Mus musculus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Homo sapiens)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Rattus norvegicus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Canis familiaris)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Bos taurus)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Sus scrofa)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Danio rerio)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Xenopus tropicalis)
Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Gallus gallus)
SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Homo sapiens)
as an output of
2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Saccharomyces cerevisiae)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Dictyostelium discoideum)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Caenorhabditis elegans)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Drosophila melanogaster)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Gallus gallus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Xenopus tropicalis)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Danio rerio)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Sus scrofa)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Bos taurus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Canis familiaris)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Rattus norvegicus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Mus musculus)
isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Homo sapiens)
TAT aminates HPP (Dictyostelium discoideum)
TAT aminates HPP (Caenorhabditis elegans)
TAT aminates HPP (Drosophila melanogaster)
TAT aminates HPP (Xenopus tropicalis)
TAT aminates HPP (Danio rerio)
TAT aminates HPP (Sus scrofa)
TAT aminates HPP (Bos taurus)
TAT aminates HPP (Canis familiaris)
TAT aminates HPP (Rattus norvegicus)
TAT aminates HPP (Mus musculus)
TAT aminates HPP (Homo sapiens)
Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane (Homo sapiens)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Saccharomyces cerevisiae)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Schizosaccharomyces pombe)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Dictyostelium discoideum)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Caenorhabditis elegans)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Drosophila melanogaster)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Gallus gallus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Xenopus tropicalis)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Sus scrofa)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Bos taurus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Canis familiaris)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Rattus norvegicus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Mus musculus)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Homo sapiens)
PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Danio rerio)
SLC25A11 exchanges 2-OG and MAL (Homo sapiens)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Canis familiaris)
SLC25A11 exchanges 2-OG and MAL (Canis familiaris)
PXLP-K314-GPT transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PXLP-K314-GPT transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
PXLP-K314-GPT transaminates PYR to form L-Ala (Dictyostelium discoideum)
PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)
PXLP-K314-GPT transaminates PYR to form L-Ala (Drosophila melanogaster)
PXLP-K314-GPT transaminates PYR to form L-Ala (Xenopus tropicalis)
PXLP-K314-GPT transaminates PYR to form L-Ala (Danio rerio)
PXLP-K314-GPT transaminates PYR to form L-Ala (Sus scrofa)
PXLP-K314-GPT transaminates PYR to form L-Ala (Bos taurus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)
PXLP-K314-GPT transaminates PYR to form L-Ala (Rattus norvegicus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)
PXLP-K314-GPT transaminates PYR to form L-Ala (Homo sapiens)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
SLC25A11 exchanges 2-OG and MAL (Drosophila melanogaster)
SLC25A11 exchanges 2-OG and MAL (Plasmodium falciparum)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)
SLC25A11 exchanges 2-OG and MAL (Caenorhabditis elegans)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Drosophila melanogaster)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Danio rerio)
SLC25A11 exchanges 2-OG and MAL (Danio rerio)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Xenopus tropicalis)
SLC25A11 exchanges 2-OG and MAL (Xenopus tropicalis)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Sus scrofa)
SLC25A11 exchanges 2-OG and MAL (Sus scrofa)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Bos taurus)
SLC25A11 exchanges 2-OG and MAL (Bos taurus)
SLC25A11 exchanges 2-OG and MAL (Rattus norvegicus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Rattus norvegicus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Mus musculus)
SLC25A11 exchanges 2-OG and MAL (Mus musculus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Saccharomyces cerevisiae)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Schizosaccharomyces pombe)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Dictyostelium discoideum)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Caenorhabditis elegans)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Drosophila melanogaster)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Gallus gallus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Xenopus tropicalis)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Danio rerio)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Sus scrofa)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Bos taurus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Canis familiaris)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Rattus norvegicus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Mus musculus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Homo sapiens)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Mus musculus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Rattus norvegicus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Canis familiaris)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Bos taurus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Sus scrofa)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Danio rerio)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Xenopus tropicalis)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Gallus gallus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Drosophila melanogaster)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Caenorhabditis elegans)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Schizosaccharomyces pombe)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Saccharomyces cerevisiae)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Homo sapiens)
Other forms of this molecule
2OG [cytoplasm]
2OG [endoplasmic reticulum lumen]
2OG [peroxisomal matrix]
2OG [mitochondrial matrix]
2OG [nucleoplasm]
2OG [extracellular region]
Cross References
KNApSAcK
C00000769
AraCyc
2-KETOGLUTARATE
CAS
328-50-7
COMPOUND
C00026
PubChem Compound
164533
ZINC
ZINC000001532519
KEGG Gene
C00026
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