Reactome | PXLP-K314-GPT transaminates PYR to form L-Ala

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PXLP-K314-GPT transaminates PYR to form L-Ala Show undefined attributes

catalystActivity	[CatalystActivity:10652735] L-alanine:2-oxoglutarate aminotransferase activity of PXLP-K314-GPT dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10652739
displayName	PXLP-K314-GPT transaminates PYR to form L-Ala
eventOf	[Pathway:R-XTR-8964540] Alanine metabolism - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala - Homo sapiens
input	[SimpleEntity:R-ALL-29404] L-Glu [cytosol] [SimpleEntity:R-ALL-29398] PYR [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PXLP-K314-GPT transaminates PYR to form L-Ala pyruvate + glutamate <=> alanine + alpha-ketoglutarate [GPT]
output	[SimpleEntity:R-ALL-29406] 2OG [cytosol] [SimpleEntity:R-ALL-29432] L-Ala [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-70524
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-8964540] Alanine metabolism
(inferredTo)	[Reaction:R-HSA-70524] PXLP-K314-GPT transaminates PYR to form L-Ala

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