leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]

catalystActivity
catalystActivityReference [CatalystActivityReference:9643740] branched-chain-amino-acid transaminase activity of BCAT1 dimer [cytosol] Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin
category transition
compartment
crossReference
dbId 70723
deleted
displayName leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]
eventOf
followingEvent
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name
  • leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1]
  • 2-oxoglutarate + L-leucine => 4-methyl-2-oxopentanoate + L-glutamate
  • 2-oxoglutarate + L-isoleucine => (S)-3-methyl-2-oxopentanoate + L-glutamate
  • 2-oxoglutarate + L-valine => 3-methyl-2-oxobutanoate + L-glutamate
negativePrecedingEvent
orthologousEvent
output
releaseDate 2004-07-06
reviewStatus [ReviewStatus:9821382] five stars
schemaClass Reaction
species
stId R-HSA-70723
summation
updateTrackers
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