BIRC2 [cytosol]

Stable Identifier
R-HSA-50847
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
c-IAP1, Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B), Baculoviral IAP repeat-containing protein 2, Inhibitor of apoptosis protein 2, HIAP2, HIAP-2, TNFR2-TRAF signaling complex protein 2, IAP homolog B
Icon
BIRC2 [cytosol] icon
BIRC2 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q13490 BIRC2
Gene Names
BIRC2, API1, MIHB, RNF48
Chain
chain:1-618
Reference Genes
BioGPS Gene:329 BIRC2
COSMIC (genes):BIRC2 BIRC2
CTD Gene:329 BIRC2
dbSNP Gene:329 BIRC2
ENSEMBL:ENSG00000110330 BIRC2
HGNC:590 BIRC2
KEGG:hsa:329 BIRC2
Monarch:329 BIRC2
NCBI Gene:329 BIRC2
OMIM:601712 BIRC2
UCSC:Q13490 BIRC2
Reference Transcript
Other Identifiers
11717627_a_at
11717628_a_at
11744694_a_at
11750887_a_at
11757937_s_at
16730540
202076_PM_at
202076_at
329
3346585
3346586
3346587
3346588
3346589
3346590
3346592
3346593
3346594
3346595
3346596
3346597
3346598
3346599
3346600
3346601
3346603
3346604
3346605
3346607
3346608
3346609
3346610
3346611
3346612
3346613
3346614
3346615
3346616
36578_at
7943424
A_14_P109450
A_14_P124015
A_14_P129741
A_14_P131109
A_24_P115774
GE59117
GO:0000209
GO:0001666
GO:0001741
GO:0001890
GO:0003713
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0005829
GO:0006355
GO:0006915
GO:0007166
GO:0007249
GO:0008270
GO:0009898
GO:0012501
GO:0014070
GO:0016740
GO:0030163
GO:0031398
GO:0032991
GO:0033209
GO:0034121
GO:0035631
GO:0038061
GO:0039535
GO:0042127
GO:0042802
GO:0042981
GO:0043027
GO:0043066
GO:0043123
GO:0043130
GO:0043161
GO:0043226
GO:0044877
GO:0045088
GO:0045471
GO:0045595
GO:0045893
GO:0046872
GO:0048856
GO:0050727
GO:0051087
GO:0051591
GO:0051726
GO:0060090
GO:0060544
GO:0060546
GO:0061630
GO:0070266
GO:0070424
GO:0071356
GO:0098770
GO:0098772
GO:0140096
GO:0140110
GO:1901222
GO:1902443
GO:1902523
GO:1902524
GO:1902527
GO:1902916
GO:2000116
GO:2000377
HMNXSV003027101
ILMN_1768194
ILMN_2182704
PH_hs_0015035
TC11000957.hg
U37547_at
g10880127_3p_at
Participates
as a member of
as an input of
as a component of
as a candidate of
Other forms of this molecule
K48pUb-BIRC2 [cytosol]
BIRC2(373-618) [cytosol]
BIRC2(1-372) [cytosol]
K63polyUb-BIRC2 [cytosol]
Inferred To
birc2 [cytosol] (Danio rerio)
birc2 [cytosol] (Xenopus tropicalis)
BIRC2 [cytosol] (Bos taurus)
BIRC2 [cytosol] (Canis familiaris)
BIRC2 [cytosol] (Drosophila melanogaster)
BIRC2 [cytosol] (Gallus gallus)
BIRC2 [cytosol] (Mus musculus)
BIRC2 [cytosol] (Schizosaccharomyces pombe)
BIRC2 [cytosol] (Sus scrofa)
Birc2 [cytosol] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
ZINC - Investigational
HPA
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (69)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q12933 TRAF2  5 0.951 19
 UniProt:P55211 CASP9  5 0.919 12
 UniProt:Q9NR28 DIABLO  2 0.825 8
 UniProt:Q96CA5 BIRC7  1 0.801 8
 UniProt:Q96HA8 NTAQ1      0.801 8
 UniProt:Q13077 TRAF1  3 0.798 8
 UniProt:P01375 TNF  5 0.788 5
 UniProt:Q9Y3E2 BOLA1      0.781 7
 UniProt:Q92844 TANK  2 0.725 5
 UniProt:Q9NQT4 EXOSC5  2 0.718 6
 UniProt:Q8N3J5 PPM1K  2 0.718 6
 UniProt:P08949-2 NMB      0.718 6
 UniProt:Q96CN9 GCC1  1 0.718 6
 UniProt:Q13546 RIPK1  20 0.697 5
 UniProt:P19438 TNFRSF1A  2 0.69 4
 UniProt:Q13490 BIRC2  5 0.667 4
 UniProt:Q9BZW7 TSG10      0.666 4
 UniProt:O43464 HTRA2  1 0.65 4
 UniProt:P55210 CASP7  5 0.641 3
 ChEBI:47922 METHYL 1-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-L-PROLYL-BETA-PHENYL-L-PHENYLALANINATE      0.618 6
 ChEBI:47924 N,N'-(HEXANE-1,6-DIYL)BIS(1-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-L-PROLYL-BETA-PHENYL-L-PHENYLALANINAMIDE)      0.618 4
 UniProt:Q9Y572 RIPK3  8 0.602 3
 UniProt:O43353 RIPK2  2 0.602 3
 UniProt:P57078 RIPK4      0.602 3
 UniProt:P40325 HUA1      0.556 3
 UniProt:A0A087WZT3 A0A087WZT3      0.556 3
 UniProt:P32502  1 0.556 3
 UniProt:P08949 NMB  1 0.556 3
 UniProt:Q06455-2 RUNX1T1      0.556 3
 IntAct:EBI-25847655 CCSB      0.556 3
 UniProt:Q01976  1 0.556 3
 UniProt:P38339  2 0.556 3
 UniProt:Q3E793 BOL1      0.556 3
 UniProt:Q8WXH2 JPH3      0.556 3
 UniProt:Q8TBB1 LNX1  1 0.556 3
 UniProt:P40937 RFC5  1 0.556 3
 UniProt:P51813 BMX  3 0.556 3
 UniProt:O60341 KDM1A  1 0.556 3
 UniProt:P51451 BLK  2 0.556 3
 UniProt:Q9UBU9 NXF1  2 0.556 3
 UniProt:P14136 GFAP  3 0.556 3
 UniProt:Q96CJ1 EAF2  1 0.556 3
 UniProt:Q9Y4C2-2 TCAF1      0.556 3
 UniProt:O75173 ADAMTS4  4 0.527 3
 UniProt:Q9NYW3 TAS2R7  1 0.527 2
 UniProt:Q9H0L4 CSTF2T  1 0.527 2
 UniProt:P19086 GNAZ  2 0.527 2
 UniProt:P00736 C1R  3 0.527 3
 UniProt:Q9Y240 CLC11      0.527 3
 UniProt:P36941 LTBR  1 0.527 3
 UniProt:P30048 PRDX3  1 0.527 2
 UniProt:Q5T6F0 DCA12      0.527 4
 UniProt:P21580 TNFAIP3  1 0.527 2
 UniProt:Q9BQK8 LPIN3  3 0.527 3
 UniProt:Q96EP0 RNF31  1 0.527 3
 UniProt:Q9NQ34 TMM9B      0.527 2
 UniProt:O75351 VPS4B  1 0.527 2
 UniProt:Q86SG7 LYG2      0.527 3
 UniProt:Q9Y6K9 IKBKG  12 0.527 3
 UniProt:P98170 XIAP  3 0.527 3
 UniProt:O75325 LRRN2      0.527 2
 UniProt:P58062 ISK7      0.527 2
 UniProt:P26842 CD27  1 0.527 2
 UniProt:Q13114 TRAF3  4 0.527 3
 UniProt:P17677 GAP43  2 0.527 2
 UniProt:Q14790 CASP8  8 0.527 2
 UniProt:P63000 RAC1  6 0.525 2
 UniProt:Q96FW1 OTUB1  2 0.499 3
 UniProt:Q9NP84 TNFRSF12A  1 0.499 2
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