CASP8(1-374)

Stable Identifier
R-HSA-3465404
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
caspase-8 p43/41 fragment, ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, MACH, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
CASP8, MCH5
Chain
propeptide:1-216, chain:217-374, propeptide:375-384, chain:385-479
Other Identifiers
0002190438
0004120471
0006900735
11728978_x_at
11741554_x_at
11742324_a_at
11749790_a_at
11754153_x_at
11756062_x_at
1302
1553306_at
1F9E
1I4E
1QDU
1QTN
2047
207686_s_at
213373_s_at
2522730
2522731
2522732
2522733
2522743
2522744
2522747
2522750
2522751
2522752
2522753
2522755
2522756
2522758
2522759
2522764
2522766
2522768
2522769
2522770
2522771
2C2Z
2FUN
2K7Z
2Y1L
3104672
31491_s_at
33774_at
33775_s_at
3H11
3KJN
3KJQ
4JJ7
4PRZ
4PS1
4ZBW
5688
5H31
5H33
5JQE
5L08
6191
8047419
841
A0A024R3Z8
A0A0A0MS31
A_14_P116206
A_14_P138041
A_23_P209389
A_24_P148499
A_24_P157087
AAB70913
AAC50602
AAC50645
AAD24962
AAK57437
AAL87628
AAL87629
AAL87630
AAL87631
AAL87632
AAY24225
AB038985
ABC67468
AC007256
AF009620
AF102139
AF102140
AF102141
AF102142
AF102143
AF102144
AF102145
AF102146
AF380342
AF422925
AF422926
AF422927
AF422928
AF422929
BAB32555
BC028223
C9JB29
CAA66853
CAA66854
CAA66855
CAA66856
CAA66857
CAA66858
CAA66859
CAB002047
CASP8
CASP8-201
CASP8-202
CASP8-203
CASP8-205
CASP8-206
CASP8-207
CASP8-212
CCDS2342
CCDS2343
CCDS2345
CCDS42798
CCDS42799
CH471063
DQ355026
E7EQ01
E7EQ06
E7ETB7
E7EVN1
EAW70253
EAW70258
ENSG00000064012
ENSP00000264274
ENSP00000264275
ENSP00000325722
ENSP00000351273
ENSP00000376087
ENSP00000376091
ENSP00000412523
ENST00000264274
ENST00000264275
ENST00000323492
ENST00000358485
ENST00000392258
ENST00000392263
ENST00000432109
EntrezGene:841
F8WF39
g4502582_3p_a_at
GE60202
GO:0000003
GO:0002376
GO:0003674
GO:0004197
GO:0004871
GO:0005123
GO:0005164
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005829
GO:0005856
GO:0005886
GO:0006508
GO:0006810
GO:0006915
GO:0006919
GO:0006950
GO:0007005
GO:0007165
GO:0007166
GO:0008150
GO:0008219
GO:0008233
GO:0008234
GO:0009056
GO:0009409
GO:0009790
GO:0010803
GO:0016032
GO:0016787
GO:0019899
GO:0022607
GO:0030101
GO:0030154
GO:0030225
GO:0031264
GO:0031265
GO:0031625
GO:0032025
GO:0032355
GO:0032496
GO:0032991
GO:0034138
GO:0034612
GO:0035666
GO:0035877
GO:0036462
GO:0039650
GO:0042110
GO:0042113
GO:0042802
GO:0042981
GO:0043005
GO:0043123
GO:0043124
GO:0043226
GO:0044297
GO:0044403
GO:0044877
GO:0045121
GO:0045471
GO:0045651
GO:0045862
GO:0046677
GO:0048856
GO:0051603
GO:0051604
GO:0060544
GO:0060715
GO:0061024
GO:0065003
GO:0070423
GO:0071260
GO:0071407
GO:0071550
GO:0097110
GO:0097153
GO:0097190
GO:0097191
GO:0097194
GO:0097199
GO:0097200
GO:0097202
GO:0097296
GO:0097342
GO:1900740
GO:1901216
GO:1902041
GO:1902042
H7BZM4
H7C0E2
HGNC:1509
HPA001302
HPA005688
HPA006191
Hs.19949.2.S2_3p_a_at
Hs2.381231.5.S1_3p_at
ILMN_1673757
ILMN_1787749
ILMN_1809313
ILMN_2377733
IPR001309
IPR001875
IPR002138
IPR011029
IPR015917
IPR016129
IPR029030
IPR033139
IPR033170
LRG_34
LRG_34t1
LRG_34t2
MIM:114480
MIM:114550
MIM:211980
MIM:601763
MIM:607271
NM_001080124
NM_001080125
NM_001228
NM_033355
NM_033356
NM_033358
NP_001073593
NP_001073594
NP_001219
NP_203519
NP_203520
NP_203522
NR_111983
PF00656
PF01335
PH_hs_0023198
PR00376
SM00031
SM00115
TC02003767.hg
U58143
U60520
uc002uxo.2
uc002uxp.2
uc002uxq.3
uc002uxr.2
uc002uxt.2
uc002uxw.2
uc010ftf.3
UPI000002AB9A
UPI000002AB9B
UPI000002AB9C
UPI000002AB9D
UPI000003AEFE
UPI0000456ECD
X98172
X98172_at
X98173
X98174
X98175
X98176
X98176_at
X98177
X98178
X98178_s_at
XM_005246885
XM_005246886
XM_005246887
XM_005246888
XM_005246889
XM_005246890
XM_005246891
XM_005246892
XM_005246894
XM_006712789
XM_006712790
XM_006712793
XM_011511969
XP_005246942
XP_005246943
XP_005246944
XP_005246945
XP_005246946
XP_005246947
XP_005246948
XP_005246949
XP_005246951
XP_006712852
XP_006712853
XP_006712856
XP_011510271
Participant Of
Other forms of this molecule
Inferred To
Interactors (25)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q13158 FADD  1 0.978 43
 UniProt:Q13546 RIPK1  9 0.956 29
 UniProt:P50591 TNFSF10  1 0.919 20
 UniProt:P25445 FAS  1 0.911 15
 UniProt:O00220 TNFRSF10A  1 0.764 9
 UniProt:P48023 FASLG  1 0.744 5
 UniProt:Q92851 CASP10  4 0.734 6
 UniProt:Q14790 CASP8  8 0.704 4
 UniProt:Q9UKL3 CASP8AP2  2 0.704 5
 UniProt:O14763 TNFRSF10B  1 0.677 5
 UniProt:P25445-1 FAS      0.669 3
 UniProt:O15519 CFLAR  1 0.669 9
 UniProt:Q15628 TRADD  1 0.643 4
 UniProt:Q13618 CUL3  3 0.602 6
 UniProt:P51572 BCAP31  5 0.589 3
 UniProt:Q9Y572 RIPK3  2 0.564 2
 UniProt:O15519-1 CFLAR  3 0.564 2
 UniProt:Q12933 TRAF2  5 0.527 3
 UniProt:Q13490 BIRC2  5 0.527 2
 UniProt:O60936 NOL3      0.524 3
 UniProt:P29350 PTPN6  5 0.524 3
 UniProt:Q969K3 RNF34  2 0.508 3
 UniProt:Q9Y3D6 FIS1      0.499 2
 UniProt:Q9UDY8 MALT1  1 0.499 10
 UniProt:P21580 TNFAIP3  1 0.499 3