Reactome | LPIN3 [endoplasmic reticulum membrane]

LPIN3 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-549160

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

lipin 3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BQK8 LPIN3

Gene Names

LPIN3, LIPN3L

Chain

chain:1-851

Reference Genes

BioGPS Gene:64900 LPIN3

COSMIC (genes):LPIN3 LPIN3

CTD Gene:64900 LPIN3

dbSNP Gene:64900 LPIN3

ENSEMBL:ENSG00000132793 LPIN3

HGNC:14451 LPIN3

KEGG:hsa:64900 LPIN3

Monarch:64900 LPIN3

NCBI Gene:64900 LPIN3

OMIM:605520 LPIN3

UCSC:Q9BQK8 LPIN3

Reference Transcript

Other Identifiers

11755861_a_at

16913811

232966_PM_at

232966_at

3885662

3885663

3885664

3885668

3885669

3885670

3885671

3885672

3885674

3885675

3885676

3885677

3885678

3885681

3885682

3885683

3885684

3885687

3885688

3885691

3885692

3885694

3885695

3885696

3885697

3885698

3885699

3885700

3885702

3885703

3885704

3885705

3885706

3885707

3885708

3885709

3885710

3885711

3885712

3885713

64900

8062658

A_24_P100695

A_33_P3393341

GO:0003713

GO:0003824

GO:0005634

GO:0005789

GO:0006355

GO:0006629

GO:0006631

GO:0008195

GO:0009062

GO:0016787

GO:0019432

GO:0032869

GO:0043226

GO:0045944

GO:0060090

GO:0140110

HMNXSV003003991

HMNXSV003004308

HMNXSV003030505

HMNXSV003034418

Hs.302510.0.S1_3p_at

ILMN_1772834

PH_hs_0002279

PH_hs_0036147

TC20000305.hg

Participates

as a candidate of

LPIN1,2,3 [endoplasmic reticulum membrane] (Homo sapiens)

as a component of

LPIN3:Mg2+ [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

p-S106-LPIN3 [nucleoplasm]

LPIN3 [nuclear envelope]

Inferred To

LPIN3 [endoplasmic reticulum membrane] (Bos taurus)

LPIN3 [endoplasmic reticulum membrane] (Canis familiaris)

LPIN3 [endoplasmic reticulum membrane] (Danio rerio)

LPIN3 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

LPIN3 [endoplasmic reticulum membrane] (Plasmodium falciparum)

LPIN3 [endoplasmic reticulum membrane] (Sus scrofa)

lpin-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

PAH1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

Lpin3 [endoplasmic reticulum membrane] (Mus musculus)

Lpin3 [endoplasmic reticulum membrane] (Rattus norvegicus)

ned1 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

Lpin [endoplasmic reticulum membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001288789.1, XP_016883509.1

Guide to Pharmacology - Targets

1437

ENSEMBL

ENST00000373257, ENST00000632009, ENSP00000487971, ENSG00000132793, ENSP00000362354

OpenTargets

ENSG00000132793

GeneCards

LPIN3

HPA

ENSG00000132793-LPIN3

PRO

Q9BQK8

Pharos - Targets

Q9BQK8

HMDB Protein

HMDBP11807

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.527	2
UniProt:Q14693 LPIN1	3	LPIN1 [endoplasmic reticulum membrane] (R-HSA-549157) LPIN1 [nuclear envelope] (R-HSA-4419927) p-S106-LPIN1 [nucleoplasm] (R-HSA-4419936)	0.527	3
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.527	2
UniProt:Q13490 BIRC2	5	BIRC2 [cytosol] (R-HSA-50847) K48pUb-BIRC2 [cytosol] (R-HSA-5675479) BIRC2(373-618) [cytosol] (R-HSA-202931) BIRC2(1-372) [cytosol] (R-HSA-202913) K63polyUb-BIRC2 [cytosol] (R-HSA-5668512)	0.527	3
UniProt:Q86US8 SMG6	1	SMG6 [cytosol] (R-HSA-927851)	0.527	2
UniProt:Q9UBN7 HDAC6	4	HDAC6 [lysosomal lumen] (R-HSA-9660002) HDAC6 [cytosol] (R-HSA-5324660) HDAC6 [late endosome lumen] (R-HSA-9659980) HDAC6 [nucleoplasm] (R-HSA-351589)	0.527	2

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