Reactome | ZNF774 [nucleoplasm]

ZNF774 [nucleoplasm]

Stable Identifier

R-HSA-3110232

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Zinc finger protein 774, ZN774_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6NX45 ZNF774

Gene Names

ZNF774

Chain

chain:1-483

Reference Genes

BioGPS Gene:342132 ZNF774

COSMIC (genes):ZNF774 ZNF774

CTD Gene:342132 ZNF774

dbSNP Gene:342132 ZNF774

ENSEMBL:ENSG00000196391 ZNF774

ENSEMBL:ENSG00000196391.11 ZNF774

HGNC:33108 ZNF774

KEGG Gene (Homo sapiens):342132 ZNF774

Monarch:342132 ZNF774

NCBI Gene:342132 ZNF774

UCSC:Q6NX45 ZNF774

Reference Transcript

RefSeq:NM_001004309.2 ZNF774

Other Identifiers

11740636_at

16804791

342132

3608097

3608098

3608099

3608100

3608101

3608103

3608105

7986004

83609_at

A_33_P3230414

A_33_P3311740

GE508734

GO:0000978

GO:0003677

GO:0005515

GO:0005634

GO:0043226

GO:0046872

HMNXSV003008944

HMNXSV003010425

ILMN_1760339

TC15000863.hg

Participates

as a candidate of

KRAB-ZNF [nucleoplasm] (Homo sapiens)

Inferred To

Dmel\CG5245 [nucleoplasm] (Drosophila melanogaster)

Homologues of ZNF774 [nucleoplasm] (Drosophila melanogaster)

Homologues of ZNF774 [nucleoplasm] (Xenopus tropicalis)

Dmel\CG4360 [nucleoplasm] (Drosophila melanogaster)

ZNF774 [nucleoplasm] (Bos taurus)

ZNF774 [nucleoplasm] (Drosophila melanogaster)

ZNF774 [nucleoplasm] (Gallus gallus)

ZNF774 [nucleoplasm] (Rattus norvegicus)

ZNF774 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001004309.2

OpenTargets

ENSG00000196391

GeneCards

Q6NX45

HPA

ENSG00000196391-ZNF774

Ensembl

ENSP00000346348, ENST00000354377, ENSG00000196391

PRO

Q6NX45

Pharos - Targets

Q6NX45

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.781	7
UniProt:Q9BUH8 BEGAIN	1	BEGAIN [cytosol] (R-HSA-6794250)	0.718	6
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.718	9
UniProt:O15397 IPO8	2	IPO8 [nucleoplasm] (R-HSA-5578747) IPO8 [cytosol] (R-HSA-5578740)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:Q9NW38 FANCL	2	FANCL [cytosol] (R-HSA-420789) FANCL [nucleoplasm] (R-HSA-419520)	0.556	3
UniProt:Q969Y2 GTPBP3	1	GTPBP3 [mitochondrial matrix] (R-HSA-6787414)	0.556	3
UniProt:P51451 BLK	2	MyrG2-BLK [plasma membrane] (R-HSA-9606871) BLK [cytosol] (R-HSA-983580)	0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:Q9NPB3 CABP2	1	CABP2 [plasma membrane] (R-HSA-9672352)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:O75771 RAD51D	1	RAD51D [nucleoplasm] (R-HSA-216920)	0.556	3
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:P84022 SMAD3	20	Ub-SMAD3 [cytosol] (R-HSA-6782830) p-S423,S425-SMAD3 D258N [cytosol] (R-HSA-3315470) p-S423,S425-SMAD3 R268C [cytosol] (R-HSA-3315075) p-S423,S425-SMAD3 R268H [cytosol] (R-HSA-3315080) SMAD3 Q316* [cytosol] (R-HSA-9668765) SMAD3 Y384* [cytosol] (R-HSA-9668782) SMAD3 W326* [cytosol] (R-HSA-9668766) SMAD3 E246* [cytosol] (R-HSA-9668776) SMAD3 Q358* [cytosol] (R-HSA-9668772) SMAD3 Q322* [cytosol] (R-HSA-9668773) SMAD3 S425F [cytosol] (R-HSA-8944158) SMAD3 E383* [cytosol] (R-HSA-9668775) SMAD3 R368* [cytosol] (R-HSA-9668768) SMAD3 Y298* [cytosol] (R-HSA-9668769) SMAD3 S425C [cytosol] (R-HSA-3308499) p-S208-SMAD3 [cytosol] (R-HSA-9731114) SMAD3 [nucleoplasm] (R-HSA-206150) 2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-2187326) Ub,p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-9773841) p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-2176471)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:P40692 MLH1	3	MLH1 S252* [nucleoplasm] (R-HSA-5444526) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 [nucleoplasm] (R-HSA-912495)	0.556	3

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