2xHP-EPAS1 [nucleoplasm]

Stable Identifier
R-HSA-1234151
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
hydroxyPro405,531-EPAS1, hydroxyPro405,531-HIF2A, EPAS1 (HIF2A) with hydroxyproline-405 and -531, Endothelial PAS domain-containing protein 1, EPAS1_HUMAN
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
EPAS1, BHLHE73, HIF2A, MOP2, PASD2
Chain
chain:1-870
Reference Transcript
Other Identifiers
0004480603
0104730576
11715411_a_at
11715412_a_at
16879721
200878_at
200879_s_at
2034
2480386
2480387
2480388
2480389
2480390
2480391
2480392
2480420
2480421
2480424
2480425
2480432
2480433
2480434
2480440
2480441
2480443
2480444
2480447
2480448
2480449
2480451
2480453
2480454
2480455
2480456
38230_at
8041781
A_23_P210210
A_23_P430120
GE59478
GE85977
GO:0000003
GO:0000228
GO:0000790
GO:0000978
GO:0000981
GO:0000987
GO:0001228
GO:0001525
GO:0001666
GO:0001892
GO:0001974
GO:0002027
GO:0002376
GO:0003013
GO:0003674
GO:0003677
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0006366
GO:0006464
GO:0006950
GO:0006979
GO:0007005
GO:0007165
GO:0007275
GO:0007601
GO:0008134
GO:0008150
GO:0009058
GO:0009790
GO:0016567
GO:0016607
GO:0019899
GO:0021700
GO:0030097
GO:0030154
GO:0030218
GO:0030324
GO:0032991
GO:0034641
GO:0035035
GO:0042415
GO:0042592
GO:0043129
GO:0043226
GO:0043565
GO:0043619
GO:0043687
GO:0045944
GO:0046982
GO:0046983
GO:0048469
GO:0048625
GO:0048646
GO:0048856
GO:0050877
GO:0055072
GO:0061418
GO:0071456
GO:0120162
Hs.8136.0.S2_3p_at
ILMN_1704753
ILMN_1760034
PH_hs_0021983
TC02000281.hg
U81984_at
g4503576_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
monohydroxylated proline at 405
Coordinate
405
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Name
monohydroxylated proline at 531
Coordinate
531
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-proline residue to one of several monohydroxylated proline residues, including 3-hydroxy-L-proline and 4-hydroxy-L-proline.
Cross References
RefSeq
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P27540 ARNT  1 0.849 7
 UniProt:Q9GZT9 EGLN1  1 0.635 3
 UniProt:P09467 FBP1  1 0.602 4
 UniProt:P60228 EIF3E  1 0.602 10
 UniProt:Q9BWF3-1 RBM4      0.576 6
 UniProt:P84022 SMAD3  21 0.573 2
 UniProt:Q8WYA1-3 ARNTL2      0.556 3
 UniProt:O00327-8 ARNTL      0.556 3
 UniProt:A0A024R8A9 A0A024R8A9      0.556 3
 UniProt:P40337 VHL  3 0.547 2
 UniProt:P40818 USP8  2 0.544 2
 UniProt:Q96RK4 BBS4  1 0.508 2
 UniProt:O60573 EIF4E2  1 0.499 2
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