Reactome | FBLN1 [extracellular region]

FBLN1 [extracellular region]

Stable Identifier

R-HSA-2161389

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Fibulin-1, FBLN1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P23142 FBLN1

Gene Names

FBLN1, PP213

Chain

signal peptide:1-29, chain:30-703

Reference Genes

BioGPS Gene:2192 FBLN1

COSMIC (genes):FBLN1 FBLN1

CTD Gene:2192 FBLN1

dbSNP Gene:2192 FBLN1

ENSEMBL:ENSG00000077942 FBLN1

ENSEMBL_homo_sapiens_GENE:ENSG00000077942.19 FBLN1

HGNC:3600 FBLN1

KEGG Gene (Homo sapiens):2192 FBLN1

Monarch:2192 FBLN1

NCBI Gene:2192 FBLN1

OMIM:135820 FBLN1

UCSC:P23142 FBLN1

Reference Transcript

Other Identifiers

11727345_s_at

11732044_at

11742092_at

11742093_x_at

11744152_a_at

11756236_a_at

11756237_a_at

11757407_x_at

16931237

201787_PM_at

201787_at

202994_PM_s_at

202994_s_at

202995_PM_s_at

202995_s_at

207834_PM_at

207834_at

207835_PM_at

207835_at

2192

38026_at

38027_at

3948642

3948643

3948657

3948663

3948664

3948668

3948669

3948671

3948673

3948674

3948677

3948678

3948680

3948681

3948682

3948683

3948686

3948688

3948695

3948699

3948700

3948701

3948702

3948703

3948704

3948705

3948707

3948708

3948721

3948722

3948723

8073775

A_23_P211631

A_23_P303113

A_33_P3249872

GE59786

GO:0001933

GO:0001968

GO:0005178

GO:0005198

GO:0005201

GO:0005509

GO:0005515

GO:0005576

GO:0005604

GO:0005615

GO:0007155

GO:0007162

GO:0007566

GO:0010628

GO:0016504

GO:0022414

GO:0023052

GO:0030198

GO:0030312

GO:0031012

GO:0036211

GO:0042060

GO:0042802

GO:0043226

GO:0044877

GO:0048146

GO:0048856

GO:0048870

GO:0051604

GO:0062023

GO:0070051

GO:0070062

GO:0070373

GO:0071635

GO:0071953

GO:0072378

GO:0098772

GO:1900025

GO:1904188

GO:1904237

GO:2000146

GO:2000647

HMNXSV003040573

Hs.79732.0.S2_3p_s_at

ILMN_1672536

ILMN_1686952

ILMN_1700541

ILMN_1710815

PH_hs_0026034

X53742_at

g4503662_3p_at

g5922006_3p_at

g5922008_3p_s_at

g5922010_3p_at

Participates

as a member of

Cross References

RefSeq

NP_006476.2, NP_006477.2, NP_006478.2, NP_001987.2

OpenTargets

ENSG00000077942

GeneCards

P23142

HPA

ENSG00000077942-FBLN1

Ensembl

ENSP00000331544, ENST00000262722, ENST00000442170, ENSP00000342212, ENSP00000262722, ENST00000327858, ENSG00000077942, ENSP00000393812, ENST00000340923

PRO

P23142

Pharos - Targets

P23142

Orphanet

16930

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02647 APOA1	11	APOA1(25-266) [secretory granule lumen] (R-HSA-350761) APOA1(25-267) [cytosol] (R-HSA-2395781) APOA1(25-267) [early endosome] (R-HSA-2429641) APOA1(25-267) [endoplasmic reticulum lumen] (R-HSA-174640) APOA1(19-266) [extracellular region] (R-HSA-264771) APOA1(25-266) [plasma membrane] (R-HSA-216742) Variant apolipoprotein AI [extracellular region] (R-HSA-976865) APOA1(25-266) [endocytic vesicle lumen] (R-HSA-2239460) p-APOA1 [endoplasmic reticulum lumen] (R-HSA-8957081) APOA1 [endoplasmic reticulum lumen] (R-HSA-8956724) APOA1(25-266) [extracellular region] (R-HSA-174720)	0.488	2
UniProt:P84022 SMAD3	20	Ub-SMAD3 [cytosol] (R-HSA-6782830) p-S423,S425-SMAD3 D258N [cytosol] (R-HSA-3315470) p-S423,S425-SMAD3 R268C [cytosol] (R-HSA-3315075) p-S423,S425-SMAD3 R268H [cytosol] (R-HSA-3315080) SMAD3 Q316* [cytosol] (R-HSA-9668765) SMAD3 Y384* [cytosol] (R-HSA-9668782) SMAD3 W326* [cytosol] (R-HSA-9668766) SMAD3 E246* [cytosol] (R-HSA-9668776) SMAD3 Q358* [cytosol] (R-HSA-9668772) SMAD3 Q322* [cytosol] (R-HSA-9668773) SMAD3 S425F [cytosol] (R-HSA-8944158) SMAD3 E383* [cytosol] (R-HSA-9668775) SMAD3 R368* [cytosol] (R-HSA-9668768) SMAD3 Y298* [cytosol] (R-HSA-9668769) SMAD3 S425C [cytosol] (R-HSA-3308499) p-S208-SMAD3 [cytosol] (R-HSA-9731114) SMAD3 [nucleoplasm] (R-HSA-206150) 2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-2187326) Ub,p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-9773841) p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-2176471)	0.488	2