Metabolism of folate and pterines

Stable Identifier
R-HSA-196757
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Metabolism of folate and pterines
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Folates are essential cofactors that provide one-carbon moieties in various states of reduction for biosynthetic reactions. Processes annotated here include transport reactions by which folates are taken up by cells and moved intracellularly, folate conjugation with glutamate (required for folate retention within a cell), and some of the key reactions in the generation of reduced folates and one-carbon derivatives of folate.
Literature References
PubMed ID Title Journal Year
10466189 Folate and vitamin B12

Scott, JM

Proc Nutr Soc 1999
11001804 Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

Lucock, M

Mol Genet Metab 2000
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
folic acid metabolic process (0046655)
Orthologous Events
Metabolism of folate and pterines (Bos taurus)
Metabolism of folate and pterines (Caenorhabditis elegans)
Metabolism of folate and pterines (Canis familiaris)
Metabolism of folate and pterines (Danio rerio)
Metabolism of folate and pterines (Dictyostelium discoideum)
Metabolism of folate and pterines (Drosophila melanogaster)
Metabolism of folate and pterines (Gallus gallus)
Metabolism of folate and pterines (Mus musculus)
Metabolism of folate and pterines (Plasmodium falciparum)
Metabolism of folate and pterines (Rattus norvegicus)
Metabolism of folate and pterines (Saccharomyces cerevisiae)
Metabolism of folate and pterines (Schizosaccharomyces pombe)
Metabolism of folate and pterines (Sus scrofa)
Metabolism of folate and pterines (Xenopus tropicalis)
Created
Jassal, B  (2007-04-24)
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