SLC19A1 transports 5-methyl-THF from extracellular region to cytosol

Stable Identifier
R-HSA-200652
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Extracellular 5-methyltetrahydrofolate import across the plasma membrane
ReviewStatus
5/5
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SLC19A1 transports 5-methyl-THF from extracellular region to cytosol
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SLC19A1 protein, associated with the plasma membrane, mediates the uptake of extracellular 5-methyltetrahydrofolate and other reduced folates (Williams and Flintoff 1995; Ferguson and Flintoff 1999).

Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

folic acid transmembrane transporter activity of SLC19A1 [plasma membrane]

Physical Entity
SLC19A1 [plasma membrane] (Homo sapiens)
Activity
folic acid transmembrane transporter activity (GO:0008517)
Orthologous Events
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Bos taurus)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Caenorhabditis elegans)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Canis familiaris)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Danio rerio)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Dictyostelium discoideum)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Drosophila melanogaster)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Gallus gallus)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Mus musculus)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Rattus norvegicus)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Sus scrofa)
SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Xenopus tropicalis)
Created
D'Eustachio, P  (2007-07-24)
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