HCOOH translocated from mitochondrial matrix to cytosol

Stable Identifier
R-HSA-6803255
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, mitochondrial matrix
ReviewStatus
5/5
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HCOOH translocated from mitochondrial matrix to cytosol
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Formate (HCOOH) is transported from the mitochondrial matrix to the cytosol, where it is reattached to tetrahydrofolate (THF). The mechanism of transport is thought to be carrier-mediated but no protein has been discovered yet (Tibbetts & Appling 2010).

Literature References
PubMed ID Title Journal Year
20645850 Compartmentalization of Mammalian folate-mediated one-carbon metabolism

Appling, DR, Tibbetts, AS

Annu. Rev. Nutr. 2010
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Authored
Jassal, B  (2015-10-05)
Reviewed
D'Eustachio, P  (2016-10-11)
Created
Jassal, B  (2015-10-05)
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