SLC25A32 transports THF from cytosol to mitochondrial matrix

Stable Identifier
R-HSA-200680
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Cytosolic tetrahydrofolate import across the inner mitochondrial membrane
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SLC25A32 protein in the inner mitochondrial membrane mediates the reversible transport of tetrahydrofolate between the cytosol and the mitochondrial matrix. Retention of tetrahydrofolate within the mitochondrial matrix is dependent on mitochondrial polyglutamate addition (Titus and Moran 2000; Chen et al. 1996).

Participants
Participates
Event Information
Catalyst Activity

folic acid transmembrane transporter activity of SLC25A32 [mitochondrial inner membrane]

Orthologous Events
Created
Cite Us!