DHFR2 reduces FOLA to DHF

Stable Identifier
R-HSA-197963
Type
Reaction
Species
Homo sapiens
Compartment
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Dihydrofolate reductase 2 (DHFR2) catalyzes the reduction of folate (FOLA) to dihydrofolate (DHF) (Chen et al. 1984).

Literature References
PubMed ID Title Journal Year
6323448 The functional human dihydrofolate reductase gene

Cline, A, Humphries, RK, Maizel, J, Moulton, AD, Chen, MJ, Shimada, T, Nienhuis, AW

J Biol Chem 1984
Participants
Participates
Catalyst Activity

folate reductase activity of DHFR2 [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Created
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