p-8Y-FGFR1c P252R [plasma membrane]

Stable Identifier
R-HSA-2011858
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-8Y-FGFR1-1 P252R
Icon
p-8Y-FGFR1c P252R [plasma membrane] icon
p-8Y-FGFR1c P252R [plasma membrane] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P11362-1 FGFR1
Gene Names
FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Participates
as a component of
Other forms of this molecule
p-8Y-FGFR1c [plasma membrane]
FGFR1c [plasma membrane]
p-8Y-FGFR1c P252T [plasma membrane]
p-8Y-FGFR1c P252S [plasma membrane]
FGFR1c P252T [plasma membrane]
FGFR1c P252S [plasma membrane]
FGFR1c P252R [plasma membrane]
Inferred To
p-8Y-FGFR1c P252T [plasma membrane] (Homo sapiens)
p-8Y-FGFR1c P252S [plasma membrane] (Homo sapiens)
Modified Residues
Name
L-proline 252 replaced with L-arginine
Coordinate
252
PsiMod
L-proline removal [MOD:01645]
A protein modification that effectively removes or replaces an L-proline.
L-arginine residue [MOD:00011]
A protein modification that effectively converts a source amino acid residue to an L-arginine.
Name
O4'-phospho-L-tyrosine at 463
Coordinate
463
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 583
Coordinate
583
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 585
Coordinate
585
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 653
Coordinate
653
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 654
Coordinate
654
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 730
Coordinate
730
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 766
Coordinate
766
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 776
Coordinate
776
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
Pfeiffer syndrome DOID:14705 acrocephalosyndactylia type V
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
IntEnz
HPA
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (25)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.912 9
 UniProt:P19174 PLCG1  6 0.903 11
 UniProt:P05230 FGF1  1 0.838 5
 UniProt:P46934 NEDD4  1 0.672 26
 UniProt:P51812 RPS6KA3  7 0.671 4
 UniProt:P08238 HSP90AB1  6 0.669 3
 UniProt:P27986 PIK3R1  16 0.644 6
 UniProt:Q8IVI9 NOSTRIN  2 0.633 5
 UniProt:P23352 ANOS1  1 0.626 7
 UniProt:P11362 FGFR1  9 0.623 4
 UniProt:P21802 FGFR2  20 0.623 3
 UniProt:P35222 CTNNB1  20 0.623 3
 UniProt:P08908 HTR1A  1 0.62 9
 UniProt:P10686 Plcg1  8 0.611 4
 UniProt:Q16543 CDC37  1 0.569 4
 UniProt:Q9NQH7 XPP3      0.569 3
 UniProt:Q8WU20 FRS2  6 0.569 3
 UniProt:O35082  2 0.558 2
 UniProt:Q9GZV9 FGF23  6 0.544 2
 UniProt:P22455 FGFR4  12 0.539 3
 UniProt:P12830 CDH1  8 0.536 3
 UniProt:Q7KZF4 SND1  2 0.483 2
 UniProt:P46108 CRK  1 0.483 2
 UniProt:P06493 CDK1  11 0.483 3
 UniProt:O88900  1 0.471 3
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