FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]

Stable Identifier
R-HSA-8853241
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
22837387 Transforming fusions of FGFR and TACC genes in human glioblastoma

Gao, Z, Sullivan, R, Niola, F, Guha, A, Zoppoli, P, Castano, A, Singh, D, Riccardi, R, Chan, JM, Finocchiaro, G, Aldape, K, Zagzag, D, Ceccarelli, M, Pellegatta, S, Porrati, P, Iavarone, A, Brat, DJ, Golfinos, JG, Rabadan, R, Qiu, K, Liu, EM, Mikkelsen, T, Reichel, J, Lasorella, A

Science 2012
External Reference Information
External Reference
Gene Names
FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Chain
signal peptide:1-21, chain:22-822
Other Identifiers
0003360142
0005220121
11716548_x_at
11727300_a_at
11727301_a_at
11734765_a_at
11747416_a_at
11747417_x_at
2056_at
2057_g_at
207937_x_at
211535_s_at
2260
226705_at
3132013
3132015
3132017
3132018
3132019
3132020
3132021
3132022
3132023
3132025
3132026
3132027
3132028
3132029
3132031
3132033
3132036
3132039
3132041
3132044
3132046
3132055
3132056
3132070
3132072
3132076
3132078
3132080
3132081
3132083
3132095
3132108
3132109
3132111
3132112
3132113
3132114
3132115
3132116
3493097
36168_at
424_s_at
53212_at
8150318
91005_at
A_23_P301304
A_23_P372923
A_24_P4171
GE59934
GO:0000165
GO:0000166
GO:0001501
GO:0001764
GO:0001837
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0005007
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005887
GO:0006464
GO:0006468
GO:0007165
GO:0007169
GO:0007275
GO:0008150
GO:0008201
GO:0008219
GO:0008283
GO:0008284
GO:0008543
GO:0009790
GO:0010518
GO:0010863
GO:0014068
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0017134
GO:0018108
GO:0030154
GO:0031410
GO:0032991
GO:0033674
GO:0040011
GO:0042802
GO:0042803
GO:0043009
GO:0043167
GO:0043226
GO:0043235
GO:0043406
GO:0043410
GO:0043536
GO:0045595
GO:0045597
GO:0045666
GO:0046777
GO:0048015
GO:0048705
GO:0048856
GO:0048870
GO:0051897
GO:0090722
GO:1905564
GO:2000546
GO:2001239
HMNXSV003006005
HMNXSV003036243
Hs.748.8.A1_3p_at
ILMN_1729369
ILMN_1796229
ILMN_2398261
PH_hs_0000085
X66945_at
g13186246_3p_a_at
g182560_3p_a_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 571 to 805 at 764 from UniProt:O75410 TACC1
Coordinate
764
Disease
Name Identifier Synonyms
glioblastoma DOID:3068 spongioblastoma multiforme, Spongioblastoma multiforme, primary glioblastoma multiforme, Glioblastoma multiforme, Glioblastoma (morphologic abnormality), GBM (Glioblastoma), Glioblastoma NOS (morphologic abnormality)
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.871 7
 UniProt:P19174 PLCG1  6 0.862 9
 UniProt:P46934 NEDD4  1 0.672 26
 UniProt:P23352 ANOS1  1 0.626 7
 UniProt:P08908 HTR1A  1 0.62 9
 UniProt:P10686 Plcg1  8 0.611 4
 UniProt:P27986 PIK3R1  15 0.569 5
 UniProt:P08238 HSP90AB1  6 0.564 2
 UniProt:Q9GZV9 FGF23  6 0.544 2
 UniProt:P12830 CDH1  10 0.536 3
 UniProt:P35222 CTNNB1  20 0.536 2
 UniProt:P46108 CRK  1 0.483 2
 UniProt:O88900  1 0.471 3
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