FGFR1 K656E [plasma membrane]

Stable Identifier
R-HSA-1614373
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
FGFR1 K656E [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18772890 Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Cancer Genome Atlas Research Network, -

Nature 2008
10918587 Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4

Tynan, JA, Donoghue, DJ, Hart, KC, Kanemitsu, MY, Robertson, SC, Meyer, AN

Oncogene 2000
Participates
Other forms of this molecule
Modified Residues
Name
L-lysine 656 replaced with L-glutamic acid
Coordinate
656
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-glutamic acid.
A protein modification that effectively removes or replaces an L-lysine.
Disease
Name Identifier Synonyms
glioblastoma DOID:3068 spongioblastoma multiforme, Spongioblastoma multiforme, primary glioblastoma multiforme, Glioblastoma multiforme, Glioblastoma (morphologic abnormality), GBM (Glioblastoma), Glioblastoma NOS (morphologic abnormality)
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (25)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.912 9
 UniProt:P19174 PLCG1  6 0.903 11
 UniProt:P05230 FGF1  1 0.838 5
 UniProt:P46934 NEDD4  1 0.672 26
 UniProt:P51812 RPS6KA3  7 0.671 4
 UniProt:P08238 HSP90AB1  6 0.669 3
 UniProt:P27986 PIK3R1  16 0.644 6
 UniProt:Q8IVI9 NOSTRIN  2 0.633 5
 UniProt:P23352 ANOS1  1 0.626 7
 UniProt:P35222 CTNNB1  20 0.623 3
 UniProt:P11362 FGFR1  9 0.623 4
 UniProt:P21802 FGFR2  20 0.623 3
 UniProt:P08908 HTR1A  1 0.62 9
 UniProt:P10686 Plcg1  8 0.611 4
 UniProt:Q16543 CDC37  1 0.569 4
 UniProt:Q9NQH7 XPP3      0.569 3
 UniProt:Q8WU20 FRS2  6 0.569 3
 UniProt:O35082  2 0.558 2
 UniProt:Q9GZV9 FGF23  6 0.544 2
 UniProt:P22455 FGFR4  12 0.539 3
 UniProt:P12830 CDH1  20 0.536 3
 UniProt:Q7KZF4 SND1  2 0.483 2
 UniProt:P06493 CDK1  11 0.483 3
 UniProt:P46108 CRK  1 0.483 2
 UniProt:O88900  1 0.471 3
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